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Photonic crystals -- a class of materials whose optical properties derive from their structure in addition to their composition -- can be created by self-assembling particles whose sizes are comparable to the wavelengths of visible light.…

Soft Condensed Matter · Physics 2023-08-02 Alexander Hensley , Thomas E. Videbaek , Hunter Seyforth , William M. Jacobs , W. Benjamin Rogers

Multivalent interactions between deformable mesoscopic units are ubiquitous in biology, where membrane macromolecules mediate the interactions between neighbouring living cells and between cells and solid substrates. Lately, analogous…

Biological Physics · Physics 2015-04-20 S. F. Shimobayashi , B. M. Mognetti , L. Parolini , D. Orsi , P. Cicuta , L. Di Michele

The melting of a homopolymer double-stranded (ds) deoxyribonucleic acid (DNA) in the dilute limit is studied numerically in the presence of an attractive and impenetrable surface on a simple cubic lattice. The two strands of the DNA are…

Soft Condensed Matter · Physics 2023-06-09 Debjyoti Majumdar

Optical mapping by direct visualization of individual DNA molecules, stretched in nanochannels with sequence-specific fluorescent labeling, represents a promising tool for disease diagnostics and genomics. An important challenge for this…

Quantitative Methods · Quantitative Biology 2015-01-21 Charleston Noble , Adam N. Nilsson , Camilla Freitag , Jason P. Beech , Jonas O. Tegenfeldt , Tobias Ambjörnsson

Metal nanostructures are key elements in nanooptics owing to their strong resonant interaction with light through local plasmonic charge oscillations. Their ability to shape light at the nanoscale have made them important across a multitude…

We show experimentally that a cheap glass microcapillary can accumulate {\lambda}-phage DNA at its tip and deliver the DNA into the capillary using a combination of electro-osmotic flow, pressure-driven flow, and electrophoresis. We develop…

The authors report on a room-temperature nanoimprinted, DNA-based distributed feedback (DFB) laser operating at 605 nm. The laser is made of a pure DNA host matrix doped with gain dyes. At high excitation densities, the emission of the…

We propose a new method for electrophoretic separation of DNA in which adsorbed polymers are driven over a disordered two-dimensional substrate which contains attractive sites for the polymers. Using simulations of a model for long polymer…

Soft Condensed Matter · Physics 2008-03-31 C. J. Olson Reichhardt , C. Reichhardt

Intercalation of drug molecules into synthetic DNA nanostructures formed through self-assembled origami has been postulated as a valuable future method for targeted drug delivery. This is due to the excellent biocompatibility of synthetic…

Deoxyribonucleic acid (DNA) has emerged as a promising building block for next-generation ultra-high density storage devices. Although DNA has high durability and extremely high density in nature, its potential as the basis of storage…

Emerging Technologies · Computer Science 2023-04-28 Arpan De , Hashem Mohammad , Yiren Wang , Rajkumar Kubendran , Arindam K. Das , M. P. Anantram

Nanochannels provide means for detailed experiments on the effect of confinement on biomacromolecules, such as DNA. We here introduce a model for the complete unfolding of DNA from the circular to linear configuration. Two main ingredients…

DNA origami is a powerful method to achieve nanoscale folded structures. Despite rapid improvements in folding and purification methods, DNA origami objects are still often produced in small quantities and studied at single molecule scale.…

Nanopores -- nanosized holes that can transport ions and molecules -- are very promising devices for genomic screening, in particular DNA sequencing. Both solid-state and biological pores suffer from the drawback, however, that the channel…

Low-energy electrons offer a unique possibility for long exposure imaging of individual biomolecules without significant radiation damage. In addition, low-energy electrons exhibit high sensitivity to local potentials and thus can be…

Mesoscale and Nanoscale Physics · Physics 2019-08-27 Tatiana Latychevskaia , Conrad Escher , William Andregg , Michael Andregg , Hans-Werner Fink

Successful isolation of graphene from graphite opened a new era for material science and con- densed matter physics. Due to this remarkable achievement, there has been an immense interest to synthesize new two dimensional materials and to…

Mesoscale and Nanoscale Physics · Physics 2016-08-11 Mehmet Yagmurcukardes , Cihan Bacaksiz , Fadıl Iyikanat , Engin Torun , R. Tugrul Senger , Francois M. Peeters , Hasan Sahin

Solid-state nanopores are emerging platforms for single-molecule protein sequencing due to their tolerance to hash physiology environment and compatibility with different electrical and optical detection methods. However, they suffer from…

Applied Physics · Physics 2024-01-05 Yingqi Zhao , Aliaksandr Hubarevich , Jian-An Huang , Francesco De Angelis

Purpose Nanopore-based molecular sensing and measurement, specifically Deoxyribonucleic acid (DNA) sequencing, is advancing at a fast pace. Some embodiments have matured from coarse particle counters to enabling full human genome assembly.…

Instrumentation and Detectors · Physics 2021-10-06 Mehdi Habibi , Yunus Dawji , Ebrahim Ghafar-Zadeh , Sebastian Magierowski

We have micromachined a silicon-chip device that transports DNA with a Brownian ratchet that rectifies the Brownian motion of microscopic particles. Transport properties for a DNA 50mer agree with theoretical predictions, and the DNA…

Deformation of single stranded DNA in translocation process before reaching the pore is investigated. By solving the Laplace equation in a suitable coordinate system and with appropriate boundary conditions, an approximate solution for the…

Soft Condensed Matter · Physics 2014-11-18 Farnoush Farahpour , Azadeh Maleknejad , Fathollah Varnik , Mohammad Reza Ejtehadi

DNA nanostructures are made using synthetic DNA strands, the sequences of which are designed such that they will self-assemble into the desired form by hybridization of complementary domains. Various structures and devices have been…

Biological Physics · Physics 2015-06-02 Katherine E. Dunn
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