Related papers: CiMBA: Accelerating Genome Sequencing through On-D…

Spiking Neural Networks (SNNs) have emerged as a biologically inspired alternative to conventional deep networks, offering event-driven and energy-efficient computation. However, their throughput remains constrained by the serial update of…

In the last few years, research and development on Deep Learning models and techniques for ultra-low-power devices in a word, TinyML has mainly focused on a train-then-deploy assumption, with static models that cannot be adapted to newly…

DNA sequencing, especially of microbial genomes and metagenomes, has been at the core of recent research advances in large-scale comparative genomics. The data deluge has resulted in exponential growth in genomic datasets over the past…

Compute-in-memory (CIM) accelerators for spiking neural networks (SNNs) are promising solutions to enable $\mu$s-level inference latency and ultra-low energy in edge vision applications. Yet, their current lack of flexibility at both the…

In today's data-centric world, where data fuels numerous application domains, with machine learning at the forefront, handling the enormous volume of data efficiently in terms of time and energy presents a formidable challenge. Conventional…

Computing-in-memory (CIM) has attracted significant attentions in recent years due to its massive parallelism and low power consumption. However, current CIM designs suffer from large area overhead of small CIM macros and bad programmablity…

U-shaped architectures have long dominated the field of medical image segmentation, while Transformers are widely employed for modeling long-range dependencies. The former typically handles scale variations implicitly by aggregating…

Convolutional neural networks (CNNs) play a key role in deep learning applications. However, the large storage overheads and the substantial computation cost of CNNs are problematic in hardware accelerators. Computing-in-memory (CIM)…

Retrieval-Augmented Generation (RAG) is crucial for improving the quality of large language models by injecting proper contexts extracted from external sources. RAG requires high-throughput, low-latency Approximate Nearest Neighbor Search…

Single-nucleus RNA sequencing (snRNA-seq) has significantly advanced our understanding of the disease etiology of neurodegenerative disorders. However, the low quality of specimens derived from postmortem brain tissues, combined with the…

Genome sequencing has become a central focus in computational biology. A genome study typically begins with sequencing, which produces millions to billions of short DNA fragments known as reads. Read mapping aligns these reads to a…

Motivation: Generative models for protein backbone design have to simultaneously ensure geometric validity, sampling efficiency, and scalability to long sequences. However, most existing approaches rely on iterative refinement, quadratic…

Recently, the state space model (SSM) represented by Mamba has shown remarkable performance in long-term sequence modeling tasks, including speech enhancement. However, due to substantial differences in sub-band features, applying the same…

Transformers have become central to natural language processing and large language models, but their deployment at scale faces three major challenges. First, the attention mechanism requires massive matrix multiplications and frequent…

Combinatorial optimization problems are funda- mental for various fields ranging from finance to wireless net- works. This work presents a simulated bifurcation (SB) Ising solver in CMOS for NP-hard optimization problems. Analog domain…

Various processing-in-memory (PIM) accelerators based on various devices, micro-architectures, and interfaces have been proposed to accelerate deep neural networks (DNNs). How to deploy DNNs onto PIM-based accelerators is the key to explore…

The rapid increase in LLM model sizes and the growing demand for long-context inference have made memory a critical bottleneck in GPU-accelerated serving systems. Although high-bandwidth memory (HBM) on GPUs offers fast access, its limited…

Compute-in-memory (CIM) based neural network accelerators offer a promising solution to the Von Neumann bottleneck by computing directly within memory arrays. However, SRAM CIM faces limitations in executing larger models due to its cell…

Learning-based lossless compressors play a crucial role in large-scale genomic database backup, storage, transmission, and management. However, their 1) inadequate compression ratio, 2) low compression \& decompression throughput, and 3)…

Resistive crossbars enabling analog In-Memory Computing (IMC) have emerged as a promising architecture for Deep Neural Network (DNN) acceleration, offering high memory bandwidth and in-situ computation. However, the manual,…