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Continual learning, the ability to acquire and transfer knowledge through a models lifetime, is critical for artificial agents that interact in real-world environments. Biological brains inherently demonstrate these capabilities while…

Neural and Evolutionary Computing · Computer Science 2025-09-09 Vedant Karia , Abdullah Zyarah , Dhireesha Kudithipudi

Transformer-based models have demonstrated superior performance in various fields, including natural language processing and computer vision. However, their enormous model size and high demands in computation, memory, and communication…

Hardware Architecture · Computer Science 2025-04-28 Ye Qiao , Zhiheng Chen , Yian Wang , Yifan Zhang , Yunzhe Deng , Sitao Huang

Access to the proper infrastructure is critical when performing medical image segmentation with Deep Learning. This requirement makes it difficult to run state-of-the-art segmentation models in resource-constrained scenarios like primary…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 John Kalkhof , Camila González , Anirban Mukhopadhyay

The Transformer architecture has shown a remarkable ability in modeling global relationships. However, it poses a significant computational challenge when processing high-dimensional medical images. This hinders its development and…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Zhaohu Xing , Tian Ye , Yijun Yang , Guang Liu , Lei Zhu

Transformers have become dominant in large-scale deep learning tasks across various domains, including text, 2D and 3D vision. However, the quadratic complexity of their attention mechanism limits their efficiency as the sequence length…

Computer Vision and Pattern Recognition · Computer Science 2024-11-04 Nursena Köprücü , Destiny Okpekpe , Antonio Orvieto

Deep neural network (DNN) inference using reduced integer precision has been shown to achieve significant improvements in memory utilization and compute throughput with little or no accuracy loss compared to full-precision floating-point.…

Hardware Architecture · Computer Science 2023-04-11 Yuzong Chen , Mohamed S. Abdelfattah

Genome-to-genome comparisons require designating anchor points, which are given by Maximum Exact Matches (MEMs) between their sequences. For large genomes this is a challenging problem and the performance of existing solutions, even in…

Data Structures and Algorithms · Computer Science 2018-05-24 Szymon Grabowski , Wojciech Bieniecki

Molecular representation learning is pivotal for various molecular property prediction tasks related to drug discovery. Robust and accurate benchmarks are essential for refining and validating current methods. Existing molecular property…

Chemical Physics · Physics 2024-06-27 Shikun Feng , Jiaxin Zheng , Yinjun Jia , Yanwen Huang , Fengfeng Zhou , Wei-Ying Ma , Yanyan Lan

Database Management Systems (DBMSs) are crucial for efficient data management and analytics, and are used in several different application domains. Due to the increasing volume of data a DBMS deals with, current processor-centric…

Hardware Architecture · Computer Science 2025-04-03 Manos Frouzakis , Juan Gómez-Luna , Geraldo F. Oliveira , Mohammad Sadrosadati , Onur Mutlu

Real-time cognitive load assessment from eye-tracking signals could potentially enable adaptive human-centered-AI such as safety-critical applications such as driver vigilance monitoring or automated flight deck assistance, yet two…

Machine Learning · Computer Science 2026-05-22 Amir Mousavi , Mohammad Sadegh Sirjani , Erfan Nourbakhsh , Mimi Xie , Rocky Slavin , Leslie Neely , John Davis , John Quarles

The fall of prices of the high-throughput genome sequencing changes the landscape of modern genomics. A number of large scale projects aimed at sequencing many human genomes are in progress. Genome sequencing also becomes an important aid…

Data Structures and Algorithms · Computer Science 2017-03-03 Sebastian Deorowicz , Agnieszka Danek , Marcin Niemiec

$\textit{De Novo}$ Genome assembly is one of the most important tasks in computational biology. ELBA is the state-of-the-art distributed-memory parallel algorithm for overlap detection and layout simplification steps of $\textit{De Novo}$…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-10-11 Minhao Li , Siyu Wang , Guanghao Wei

Content addressable memory (CAM) stands out as an efficient hardware solution for memory-intensive search operations by supporting parallel computation in memory. However, developing a CAM-based accelerator architecture that achieves…

Hardware Architecture · Computer Science 2024-03-11 Mengyuan Li , Shiyi Liu , Mohammad Mehdi Sharifi , X. Sharon Hu

In recent years, various computing-in-memory (CIM) processors have been presented, showing superior performance over traditional architectures. To unleash the potential of various CIM architectures, such as device precision, crossbar size,…

Hardware Architecture · Computer Science 2024-05-09 Songyun Qu , Shixin Zhao , Bing Li , Yintao He , Xuyi Cai , Lei Zhang , Ying Wang

In data-scarce scenarios, deep learning models often overfit to noise and irrelevant patterns, which limits their ability to generalize to unseen samples. To address these challenges in medical image segmentation, we introduce Diff-UMamba,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Dhruv Jain , Romain Modzelewski , Romain Herault , Clement Chatelain , Eva Torfeh , Sebastien Thureau

The increasing complexity of transformer models in artificial intelligence expands their computational costs, memory usage, and energy consumption. Hardware acceleration tackles the ensuing challenges by designing processors and…

Hardware Architecture · Computer Science 2023-12-21 Alireza Amirshahi , Giovanni Ansaloni , David Atienza

Running Large Language Models (LLMs) on edge devices is constrained by high compute and memory demands posing a barrier for real-time applications in sectors like healthcare, education, and embedded systems. Current solutions such as…

Computational methods are the most effective tools we have besides scientific experiments to explore the properties of complex biological systems. Progress is slowing because digital silicon computers have reached their limits in terms of…

Quantum Physics · Physics 2020-04-03 Viv Kendon

Rapid development of modern sequencing platforms enabled an unprecedented growth of protein families databases. The abundance of sets composed of hundreds of thousands sequences is a great challenge for multiple sequence alignment…

Genomics · Quantitative Biology 2017-03-03 Sebastin Deorowicz , Agnieszka Debudaj-Grabysz , Adam Gudys

On-device learning allows AI models to adapt to user data, thereby enhancing service quality on edge platforms. However, training AI on resource-limited devices poses significant challenges due to the demanding computing workload and the…

Hardware Architecture · Computer Science 2023-12-27 Sai Qian Zhang , Thierry Tambe , Nestor Cuevas , Gu-Yeon Wei , David Brooks
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