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Related papers: CiMBA: Accelerating Genome Sequencing through On-D…

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Computational memory (CM) is a promising approach for accelerating inference on neural networks (NN) by using enhanced memories that, in addition to storing data, allow computations on them. One of the main challenges of this approach is…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-04-27 Kornilios Kourtis , Martino Dazzi , Nikolas Ioannou , Tobias Grosser , Abu Sebastian , Evangelos Eleftheriou

Expanding Deep Learning applications toward edge computing demands architectures capable of delivering high computational performance and efficiency while adhering to tight power and memory constraints. Digital In-Memory Computing (DIMC)…

Hardware Architecture · Computer Science 2026-02-03 Tommaso Spagnolo , Cristina Silvano , Riccardo Massa , Filippo Grillotti , Thomas Boesch , Giuseppe Desoli

Modern data-intensive applications demand high computation capabilities with strict power constraints. Unfortunately, such applications suffer from a significant waste of both execution cycles and energy in current computing systems due to…

Hardware Architecture · Computer Science 2021-07-06 Gagandeep Singh , Mohammed Alser , Damla Senol Cali , Dionysios Diamantopoulos , Juan Gómez-Luna , Henk Corporaal , Onur Mutlu

In-Memory Acceleration (IMA) promises major efficiency improvements in deep neural network (DNN) inference, but challenges remain in the integration of IMA within a digital system. We propose a heterogeneous architecture coupling 8 RISC-V…

Hardware Architecture · Computer Science 2021-09-06 Gianmarco Ottavi , Geethan Karunaratne , Francesco Conti , Irem Boybat , Luca Benini , Davide Rossi

Processing-in-memory (PIM) has emerged as a promising solution for accelerating memory-intensive workloads as they provide high memory bandwidth to the processing units. This approach has drawn attention not only from the academic community…

Hardware Architecture · Computer Science 2024-09-11 Dongjae Lee , Bongjoon Hyun , Taehun Kim , Minsoo Rhu

Our ISCA 2015 paper provides a new programmable processing-in-memory (PIM) architecture and system design that can accelerate key data-intensive applications, with a focus on graph processing workloads. Our major idea was to completely…

Hardware Architecture · Computer Science 2023-06-28 Junwhan Ahn , Sungpack Hong , Sungjoo Yoo , Onur Mutlu , Kiyoung Choi

Emerging ReRAM-based accelerators process neural networks via analog Computing-in-Memory (CiM) for ultra-high energy efficiency. However, significant overhead in peripheral circuits and complex nonlinear activation modes constrain system…

Hardware Architecture · Computer Science 2024-12-31 Peng Dang , Huawei Li , Wei Wang

Database search and clustering are fundamental components of many data analytics problems, such as mass spectrometry-driven proteomics. Traditional full clustering and search algorithms suffer from high resource usage and long latencies. We…

Databases · Computer Science 2025-11-25 Md Mizanur Rahaman Nayan , Zheyu Li , Flavio Ponzina , Sumukh Pinge , Tajana Rosing , Azad J. Naeemi

Computing-in-memory (CIM) is an emerging computing paradigm, offering noteworthy potential for accelerating neural networks with high parallelism, low latency, and energy efficiency compared to conventional von Neumann architectures.…

Neural and Evolutionary Computing · Computer Science 2024-09-30 Kam Chi Loong , Shihao Han , Sishuo Liu , Ning Lin , Zhongrui Wang

Sequence alignment is a memory bound computation whose performance in modern systems is limited by the memory bandwidth bottleneck. Processing-in-memory architectures alleviate this bottleneck by providing the memory with computing…

Hardware Architecture · Computer Science 2023-03-28 Safaa Diab , Amir Nassereldine , Mohammed Alser , Juan Gómez-Luna , Onur Mutlu , Izzat El Hajj

Large language models (LLMs) face significant inference latency due to inefficiencies in GEMM operations, weight access, and KV cache access, especially in real-time scenarios. This highlights the need for a versatile compute-memory…

Hardware Architecture · Computer Science 2025-09-15 Huizheng Wang , Zichuan Wang , Zhiheng Yue , Yousheng Long , Taiquan Wei , Jianxun Yang , Yang Wang , Chao Li , Shaojun Wei , Yang Hu , Shouyi Yin

The 3D point cloud perception has emerged as a fundamental role for a wide range of applications. In particular, with the rapid development of neural networks, the voxel-based networks attract great attention due to their excellent…

Hardware Architecture · Computer Science 2024-10-01 Xipeng Lin , Shanshi Huang , Hongwu Jiang

Computing in-memory (CiM) has emerged as an attractive technique to mitigate the von-Neumann bottleneck. Current digital CiM approaches for in-memory operands are based on multi-wordline assertion for computing bit-wise Boolean functions…

Hardware Architecture · Computer Science 2022-01-25 Akul Malhotra , Atanu K. Saha , Chunguang Wang , Sumeet K. Gupta

In-memory computing (IMC) on a monolithic chip for deep learning faces dramatic challenges on area, yield, and on-chip interconnection cost due to the ever-increasing model sizes. 2.5D integration or chiplet-based architectures interconnect…

Machine Learning · Computer Science 2021-08-23 Gokul Krishnan , Sumit K. Mandal , Manvitha Pannala , Chaitali Chakrabarti , Jae-sun Seo , Umit Y. Ogras , Yu Cao

Deploying Retrieval-Augmented Generation (RAG) on edge devices is in high demand, but is hindered by the latency of massive data movement and computation on traditional architectures. Compute-in-Memory (CiM) architectures address this…

Emerging Technologies · Computer Science 2026-04-01 Xinzhao Li , Alptekin Vardar , Franz Müller , Navya Goli , Umamaheswara Rao Tida , Kai Ni , Xiaobo Sharon Hu , Thomas Kämpfe , Ruiyang Qin

Motivation: Read mapping is a computationally expensive process and a major bottleneck in genomics analyses. The performance of read mapping is mainly limited by the performance of three key computational steps: Index Querying, Seed…

Hardware Architecture · Computer Science 2023-10-02 Julien Eudine , Mohammed Alser , Gagandeep Singh , Can Alkan , Onur Mutlu

The rise of data-intensive applications exposed the limitations of conventional processor-centric von-Neumann architectures that struggle to meet the off-chip memory bandwidth demand. Therefore, recent innovations in computer architecture…

Hardware Architecture · Computer Science 2024-05-28 Asif Ali Khan , Hamid Farzaneh , Karl F. A. Friebel , Clément Fournier , Lorenzo Chelini , Jeronimo Castrillon

State-Space Models (SSMs) have emerged as efficient alternatives to transformers for sequential data tasks, offering linear or near-linear scalability with sequence length, making them ideal for long-sequence applications in NLP, vision,…

Machine Learning · Computer Science 2025-04-01 Arghadip Das , Arnab Raha , Shamik Kundu , Soumendu Kumar Ghosh , Deepak Mathaikutty , Vijay Raghunathan

The number of parameters in deep neural networks (DNNs) is rapidly increasing to support complicated tasks and to improve model accuracy. Correspondingly, the amount of computations and required memory footprint increase as well.…

Machine Learning · Computer Science 2020-09-01 Yongkweon Jeon , Baeseong Park , Se Jung Kwon , Byeongwook Kim , Jeongin Yun , Dongsoo Lee

The ability to quickly and accurately identify microbial species in a sample, known as metagenomic profiling, is critical across various fields, from healthcare to environmental science. This paper introduces a novel method to profile…

Genomics · Quantitative Biology 2025-04-10 Riselda Kodra , Hadjer Benmeziane , Irem Boybat , William Andrew Simon