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Pre-trained vision models (PVMs) have demonstrated remarkable adaptability across a wide range of downstream vision tasks, showcasing exceptional performance. However, as these models scale to billions or even trillions of parameters,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-10 Yi Xin , Jianjiang Yang , Siqi Luo , Yuntao Du , Qi Qin , Kangrui Cen , Yangfan He , Zhiwei Zhang , Bin Fu , Xiaokang Yang , Guangtao Zhai , Ming-Hsuan Yang , Xiaohong Liu

In recent years, machine learning models have been increasingly applied to spectroscopic datasets for chemical and biomedical analysis. For their successful adoption, particularly in clinical and safety-critical settings, professionals and…

Recently, many foundation models for medical image analysis such as MedSAM, SwinUNETR have been released and proven to be useful in multiple tasks. However, considering the inherent heterogeneity and inhomogeneity of real-world medical…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Shangde Gao , Yichao Fu , Ke Liu , Hongxia Xu , Jian Wu

Modern financial systems generate vast quantities of transactional and event-level data that encode rich economic signals. This paper presents PRAGMA, a family of foundation models for multi-source banking event sequences. Our approach…

More music foundation models are recently being released, promising a general, mostly task independent encoding of musical information. Common ways of adapting music foundation models to downstream tasks are probing and fine-tuning. These…

Sound · Computer Science 2024-12-02 Yiwei Ding , Alexander Lerch

Learning deep neural networks that are generalizable across different domains remains a challenge due to the problem of domain shift. Unsupervised domain adaptation is a promising avenue which transfers knowledge from a source domain to a…

Machine Learning · Computer Science 2020-08-20 Qingjie Meng , Daniel Rueckert , Bernhard Kainz

Predicting spatial gene expression from H&E histology offers a scalable and clinically accessible alternative to sequencing, but realizing clinical impact requires models that generalize across cancer types and capture biologically coherent…

Machine Learning · Computer Science 2026-02-10 Susu Hu , Qinghe Zeng , Nithya Bhasker , Jakob Nikolas Kather , Stefanie Speidel

Finite Element Analysis (FEA) is a powerful but computationally intensive method for simulating physical phenomena. Recent advancements in machine learning have led to surrogate models capable of accelerating FEA. Yet there are still…

Machine Learning · Computer Science 2025-02-18 Georgios Triantafyllou , Panagiotis G. Kalozoumis , George Dimas , Dimitris K. Iakovidis

This study addresses the challenges of symptom evolution complexity and insufficient temporal dependency modeling in Parkinson's disease progression prediction. It proposes a unified prediction framework that integrates structural…

Machine Learning · Computer Science 2025-08-22 Jiacheng Hu , Bo Zhang , Ting Xu , Haifeng Yang , Min Gao

Traditional sheet metal forming relies on time-consuming and expensive Finite Element Analysis (FEA) for design validation, a process that significantly prolongs design cycles. While surrogate models offer faster iteration, current…

Machine Learning · Computer Science 2026-05-20 Jiajie Luo , Mohamed Mohamed , Osama Hassan , Haosu Zhou , Yingxue Zhao , Haoran Li , Xinrun Li , Zhutao Shao , Yang Long , Nan Li , Jichun Li

Recent advances in generic large models, such as GPT and DeepSeek, have motivated the introduction of universality to graph pre-training, aiming to learn rich and generalizable knowledge across diverse domains using graph representations to…

Machine Learning · Computer Science 2026-02-27 Lianze Shan , Jitao Zhao , Dongxiao He , Siqi Liu , Jiaxu Cui , Weixiong Zhang

Predictive modeling based on genomic data has gained popularity in biomedical research and clinical practice by allowing researchers and clinicians to identify biomarkers and tailor treatment decisions more efficiently. Analysis…

Machine Learning · Statistics 2021-02-02 Li Zeng , Zhaolong Yu , Yiliang Zhang , Hongyu Zhao

Recent advances in Diffusion Transformers (DiTs) demonstrate that aligning noisy latent states with well-trained semantic features-as pioneered by Representation Alignment (REPA)-can substantially accelerate training and improve generation…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Shaodong Xu , Zhendong Wang , Litong Gong , Zexian Li , Wengang Zhou , Tiezheng Ge , Houqiang Li

Electron microscopy (EM) imaging offers unparalleled resolution for analyzing neural tissues, crucial for uncovering the intricacies of synaptic connections and neural processes fundamental to understanding behavioral mechanisms. Recently,…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Ruohua Shi , Qiufan Pang , Lei Ma , Lingyu Duan , Tiejun Huang , Tingting Jiang

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

Probabilistic time series forecasting is crucial in many application domains such as retail, ecommerce, finance, or biology. With the increasing availability of large volumes of data, a number of neural architectures have been proposed for…

Machine Learning · Computer Science 2021-12-15 Olivier Sprangers , Sebastian Schelter , Maarten de Rijke

The proliferation of omics datasets in public repositories has created unprecedented opportunities for biomedical research but has also posed significant challenges for their integration, particularly due to missing genes and…

Understanding how small molecules perturb gene expression is essential for uncovering drug mechanisms, predicting off-target effects, and identifying repurposing opportunities. While prior deep learning frameworks have integrated multimodal…

Machine Learning · Computer Science 2026-01-01 Pascal Passigan , Kevin Zhu , Angelina Ning

We propose a probabilistic model for interpreting gene expression levels that are observed through single-cell RNA sequencing. In the model, each cell has a low-dimensional latent representation. Additional latent variables account for…

Machine Learning · Computer Science 2018-01-18 Romain Lopez , Jeffrey Regier , Michael Cole , Michael Jordan , Nir Yosef

Ensemble of machine learning models yields improved performance as well as robustness. However, their memory requirements and inference costs can be prohibitively high. Knowledge distillation is an approach that allows a single model to…

Computer Vision and Pattern Recognition · Computer Science 2022-10-06 Zhengcong Fei , Shuman Tian , Junshi Huang , Xiaoming Wei , Xiaolin Wei