Related papers: Multi-Frequency Reverberant Shear Waves for Assess…
Objective: Survival rate of oral squamous cell carcinoma (OSCC) patients is very poor and can be improved using highly sensitive, specific and accurate techniques. Autofluorescence and fluorescence techniques are very sensitive and useful…
Tissue stiffness is related to soft tissue pathologies and can be assessed through palpation or via clinical imaging systems, e.g., ultrasound or magnetic resonance imaging. Typically, the image based approaches are not suitable during…
Magnetic Resonance Elastography (MRE) can characterize biomechanical properties of soft tissue for disease diagnosis and treatment planning. However, complicated wavefields acquired from MRE coupled with noise pose challenges for accurate…
We demonstrate an ultrahigh-speed optical coherence tomography (OCT) based on a 100 MHz swept source (SS). An all polarization-maintaining figure-9 mode-locked fiber laser is used as the seed laser. After nonlinear spectral expansion in an…
Optical coherence tomography (OCT) is a powerful biomedical imaging technology that relies on the coherent detection of backscattered light to image tissue morphology in vivo. As a consequence, OCT is susceptible to coherent noise (speckle…
The recent development of opto-mechano-fluidic resonators has provided -- by harnessing photon radiation pressure -- a new microfluidics platform for the optical sensing of fluid density and bulk modulus. Here we show that fluid viscosity…
Magnetic Resonance Elastography allows noninvasive visualization of tissue mechanical properties by measuring the displacements resulting from applied stresses, and fitting a mechanical model. Poroelasticity naturally lends itself to…
Ultrasound Shear Wave Elastography (USWE) with conventional B-mode imaging demonstrates better performance in lesion segmentation and classification problems. In this article, we propose SHEAR-net, an end-to-end deep neural network, to…
Optical coherence tomography (OCT) is a powerful and noninvasive method for retinal imaging. In this paper, we introduce a fast segmentation method based on a new variant of spectral graph theory named diffusion maps. The research is…
The objective of this study was to investigate the relationship between erectile pressure (EP) and shear wave speed of the corpus cavernosa obtained via a specific ultrasound vibro-elastography (UVE) technique. This study builds upon our…
Objective: Ultrasound Shear Wave Elastography (SWE) demonstrates great potential in assessing soft-tissue pathology by mapping tissue stiffness, which is linked to malignancy. Traditional SWE methods have shown promise in estimating tissue…
Optical coherence tomography (OCT) is a high-resolution three-dimensional imaging technique that enables non-destructive measurements of surface and subsurface microstructures. Recent developments of OCT operating in the mid-infrared (MIR)…
Modern optical coherence tomography (OCT) devices provide volumetric images with micrometer-scale spatial resolution and a temporal resolution beyond video rate. In this work, we analyze an OCT-based prototypical tracking system which…
We provide a mathematical analysis of and a numerical framework for full-field optical coherence elastography, which has unique features including micron-scale resolution, real-time processing, and non-invasive imaging. We develop a novel…
Visible light optical coherence tomography (vis-OCT) provides a unique tool for imaging the structure and oxygen metabolism in tissues. However, since it works in the spectral domain, vis-OCT still suffers from noises due to the multiple…
The cornea provides the largest refractive power for the human visual system. Its stiffness, along with intraocular pressure (IOP), are linked to several pathologies, including keratoconus and glaucoma. Although mechanical tests can…
We present a numerical analysis of the rheology of a suspension of red blood cells (RBCs) for different volume fractions in a wall-bounded, effectively inertialess, small amplitude oscillatory shear (SAOS) flow for a wide range of applied…
Elastic properties of arteries have long been recognized as playing a major role in the cardiovascular system. However, non-invasive in vivo assessment of local arterial stiffness remains challenging and imprecise as current techniques rely…
In a recent work, Wyss, {\it et.al.} [Phys. Rev. Lett., {\bf 98}, 238303 (2007)] have noted a property of `soft solids' under oscillatory shear, the so-called strain-rate frequency superposition (SRFS). We extend this study to the case of…
A rising wave of technologies and instruments are enabling more labs and clinics to make a variety of measurements related to tissue viscoelastic properties. These instruments include elastography imaging scanners, rheological shear…