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We present a comprehensive computational model to simulate the coupled dynamics of aqueous humor flow and heat transfer in the human eye. To manage the complexity of the model, we make significant efforts in meshing and efficient solution…

Analysis of PDEs · Mathematics 2026-03-25 Thomas Saigre , Vincent Chabannes , Christophe Prud'Homme , Marcela Szopos

A one - parameter dynamical system is associated to the mathematical problem governing the membrane excitability of a ventricular cardiomyocyte, according to the Luo-Rudy I model. An algorithm used to construct the equilibrium curve is…

Mobile eye-tracking systems have been available for about a decade now and are becoming increasingly popular in different fields of application, including marketing, sociology, usability studies and linguistics. While the user-friendliness…

Computer Vision and Pattern Recognition · Computer Science 2020-07-10 Timothy Callemein , Kristof Van Beeck , Geert Brône , Toon Goedemé

Physical exercise has significant benefits for humans in improving the health and quality of their lives, by improving the functional performance of their cardiovascular and respiratory systems. However, it is very important to control the…

Quantitative Methods · Quantitative Biology 2014-03-28 Dur-e-Zehra Baig

We present a loosely coupled scheme for the numerical simulation of the cardiac electro-fluid-structure interaction problem, whose solution is typically computationally intensive due to the need to suitably treat the coupling of the…

Numerical Analysis · Mathematics 2023-08-09 Michele Bucelli , Martin Geraint Gabriel , Giacomo Gigante , Alfio Quarteroni , Christian Vergara

We introduce a multiphysics and geometric multiscale computational model, suitable to describe the hemodynamics of the whole human heart, driven by a four-chamber electromechanical model. We first present a study on the calibration of the…

Numerical Analysis · Mathematics 2024-03-06 Alberto Zingaro , Michele Bucelli , Roberto Piersanti , Francesco Regazzoni , Luca Dede' , Alfio Quarteroni

It is well known that in the computational fluid dynamics simulations related to the cardiovascular system the enforcement of outflow boundary conditions is a crucial point. In fact, they highly affect the computed flow and a wrong setup…

Fluid Dynamics · Physics 2025-03-05 Zahra Mirzaiyan , Michele Girfoglio , Gianluigi Rozza

Each year, approximately 300,000 heart valve repair or replacement procedures are performed worldwide, including approximately 70,000 aortic valve replacement surgeries in the United States alone. This paper describes progress in…

A two-dimensional mathematical model for dynamics of endothelial cells in angiogenesis is investigated. Angiogenesis is a morphogenic process in which new blood vessels emerge from an existing vascular network. Recently a one-dimensional…

Pattern Formation and Solitons · Physics 2022-01-11 Tatsuya Hayashi , Fumitaka Yura , Jun Mada , Hiroki Kurihara , Tetsuji Tokihiro

Analysing the haemodynamics of flow in carotid artery disease serves as a means to better understand the development and progression of associated complex diseases. Carotid artery disease can predispose people to major adverse…

Cardiocirculatory mathematical models serve as valuable tools for investigating physiological and pathological conditions of the circulatory system. To investigate the clinical condition of an individual, cardiocirculatory models need to be…

Physical interactive robotics, ranging from wearable devices to collaborative humanoid robots, require close coordination between mechanical design and control. However, evaluating interactive dynamics is challenging due to complex human…

Robotics · Computer Science 2026-03-11 Chenhui Zuo , Jinhao Xu , Michael Qian Vergnolle , Yanan Sui

Eye movement data are outputs of an analyser tracking the gaze when a person is inspecting a scene. These kind of data are of increasing importance in scientific research as well as in applications, e.g. in marketing and man-machine…

Methodology · Statistics 2016-07-13 Antti Penttinen , Anna-Kaisa Ylitalo

Ophthalmic decision-making depends on subtle lesion-scale cues interpreted across multimodal imaging and over time, yet most medical foundation models remain static and degrade under modality and acquisition shifts. Here we introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ziyu Gao , Xinyuan Wu , Xiaolan Chen , Zhuoran Liu , Ruoyu Chen , Bowen Liu , Bingjie Yan , Zhenhan Wang , Kai Jin , Jiancheng Yang , Yih Chung Tham , Mingguang He , Danli Shi

To address the issue of computational efficiency related to the modelling of blood flow in complex networks, we derive a family of nonlinear lumped-parameter models for blood flow in compliant vessels departing from a well-established…

Numerical Analysis · Mathematics 2022-01-06 Beatrice Ghitti , Eleuterio F. Toro , Lucas O. Müller

This paper presents eye2vec, an infrastructure for analyzing software developers' eye movements while reading source code. In common eye-tracking studies in program comprehension, researchers must preselect analysis targets such as control…

Software Engineering · Computer Science 2025-10-16 Haruhiko Yoshioka , Kazumasa Shimari , Hidetake Uwano , Kenichi Matsumoto

We present a reduced-order heart model with the aim of introducing a novel point of view in the interpretation of the pressure-volume loops. The novelty of the approach is based on the definition of active contraction as opposed to that of…

Tissues and Organs · Quantitative Biology 2010-05-31 Paola Nardinocchi , Luciano Teresi , Valerio Varano

A new model is suggested and used to mimic various spatial or temporal designs in biological or non biological formations where the focus is on the normal or irregular electrical signals coming from human heart (ECG) or brain (EEG). The…

Biological Physics · Physics 2008-07-08 Caglar Tuncay

Pulsatile changes in retinal vascular geometry over the cardiac cycle have clinical implications for the diagnosis of ocular and systemic vascular diseases, including ischemia, coronary heart diseases, and diabetes mellitus and its…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Pranjal Rai , Sachin Jangir , Tanvir Singh Bal

Personalized virtual heart models have demonstrated increasing potential for clinical use, although the estimation of their parameters given patient-specific data remain a challenge. Traditional physics-based modeling approaches are…

Signal Processing · Electrical Eng. & Systems 2024-03-26 Xiajun Jiang , Sumeet Vadhavkar , Yubo Ye , Maryam Toloubidokhti , Ryan Missel , Linwei Wang
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