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In a recent paper [PRL 91, 138103 (2003)] a new mechanism to explain the cold denaturation of proteins, based on the loss of local low-density water structure, has been proposed. In the present paper this mechanism is tested by means of…

Other Condensed Matter · Physics 2009-11-11 Manuel I. Marques

Egg yolks are an excellent model for studying sol-gel transitions, particularly the power law viscoelasticity that defines the critical point of gelation. However, prior studies lack comprehensive datasets and fail to visualize flow…

Soft Condensed Matter · Physics 2025-04-09 Maxwell Marsh , Mohammad Tanver Hossain , Randy Ewoldt

In this paper, we report a novel experimental and theoretical study to examine the response of a soft capsule bathed in a liquid environment to sudden external impacts. Taking an egg yolk as an example, we found that the soft matter is not…

Soft Condensed Matter · Physics 2021-02-24 Ji Lang , Rungun Nathan , Qianhong Wu

We address the issue of structure changes of a canola protein gel (as a solid food model) during gastrointestinal digestion. We present a method for synchrotron Small-Angle X-ray Scattering analysis of the digestion of a gel in a capillary.…

Quantitative Methods · Quantitative Biology 2023-10-27 Maja Napieraj , Annie Brûlet , Javier Perez , François Boué , Evelyne Lutton

We explain the physical basis of a model for small globular proteins with water interactions. The water is supposed to access the protein interior in an "all-or-none" manner during the unfolding of the protein chain. As a consequence of…

Condensed Matter · Physics 2009-10-31 Audun Bakk , Alex Hansen , Kim Sneppen

We study light-activated quasi-2d gels made of a colloidal network doped with Janus particles. Following the gel formation, the internal dynamics of the gel are monitored before, during, and after the light activation. We monitor both the…

Soft Condensed Matter · Physics 2023-07-11 Mengshi Wei , Matan Ben Zion , Olivier Dauchot

The mechanisms of cold- and pressure-denaturation of proteins are matter of debate and are commonly understood as due to water-mediated interactions. Here we study several cases of proteins, with or without a unique native state, with or…

Biological Physics · Physics 2026-01-13 Valentino Bianco , Giancarlo Franzese

We introduce a simple model, a binary mixture of patchy particles, which has been designed to form a gel upon heating. Due to the specific nature of the particle interactions, notably the number and geometry of the patches as well as their…

Soft Condensed Matter · Physics 2013-10-16 Sandalo Roldan-Vargas , Frank Smallenburg , Walter Kob , Francesco Sciortino

While processing at elevated temperatures, starchy food products undergo gelatinization, which leads to softening related changes in textural characteristics. Study of role of gelatinization in texture development is limited; specifically,…

Computational Physics · Physics 2018-08-07 Ankita Sinha , Atul Bhargav

The melting transition of deoxyribonucleic acid (DNA), whereby the strands of the double helix structure completely separate at a certain temperature, has been characterized using neutron scattering. A Bragg peak from B-form fibre DNA has…

From microactuators to biological tissues, non-porous materials with the ability to strongly expand when in contact with a solvent are ubiquitous. Consequently, the swelling of polymer systems such as hydrogel has received recently much…

Soft Condensed Matter · Physics 2024-11-04 George T. Fortune , Merlin A. Etzold , Julien R. Landel , Stuart B. Dalziel

Membrane and nuclear proteins of poor solubility have been separated by high resolution two-dimensional (2-D) gel electrophoresis. Isoelectric focusing with immobilized pH gradients leads to severe quantitative losses of proteins in the…

Genomics · Quantitative Biology 2007-05-23 T. Rabilloud , C. Adessi , A. Giraudel , J. Lunardi

Using a structure-based coarse-grained model of proteins, we study the mechanism of unfolding of knotted proteins through heating. We find that the dominant mechanisms of unfolding depend on the temperature applied and are generally…

Biomolecules · Quantitative Biology 2017-01-23 Yani Zhao , Mateusz Chwastyk , Marek Cieplak

Protein flotation is a process in which protein molecules are enriched by adsorption at rising bubbles. The bubbles then form a foam above the solution, where the liquid drains down and the dried foam, which is concentrated in protein, is…

Bubble growth, departure and sliding in low-pressure flow boiling has received considerable attention in the past. However, most applications of boiling heat transfer rely on high-pressure flow boiling, for which very little is known, as…

Fluid Dynamics · Physics 2024-05-29 Artyom Kossolapov , Matthew T. Hughes , Bren Phillips , Matteo Bucci

Pattern formation in drying protein droplets continues to attract considerable research attention because it can be linked to specific protein-protein interactions. An extensive study of the drying evolution and the final crack patterns are…

Soft Condensed Matter · Physics 2020-04-14 Anusuya Pal , Amalesh Gope , Ari S. Athair , Germano S. Iannacchione

We describe several unexpected phenomena, caused by a solid-solid phase transition (gel-to-crystal) typical for all main classes of lipid substances - phospholipids, triglycerides, diglycerides, alkanes, etc. We discovered that this…

Materials Science · Physics 2020-08-26 Diana Cholakova , Desislava Glushkova , Slavka Tcholakova , Nikolai Denkov

We carry out a coarse-grained molecular dynamics simulation of phospholipid vesicles with transmembrane proteins. We measure the mean and Gaussian curvatures of our protein-embedded vesicles and quantitatively show how protein clusters…

Soft Condensed Matter · Physics 2011-02-01 Amir Houshang Bahrami , Mir Abbas Jalali

We study cold denaturation of proteins at high pressures. Using multicanonical Monte Carlo simulations of a model protein in a water bath, we investigate the effect of water density fluctuations on protein stability. We find that above the…

Soft Condensed Matter · Physics 2009-11-07 Manuel I. Marques , Jose M. Borreguero , H. Eugene Stanley , Nikolay V. Dokholyan
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