The thermal denaturation of DNA studied with neutron scattering
Statistical Mechanics
2011-02-02 v1 Biological Physics
Abstract
The melting transition of deoxyribonucleic acid (DNA), whereby the strands of the double helix structure completely separate at a certain temperature, has been characterized using neutron scattering. A Bragg peak from B-form fibre DNA has been measured as a function of temperature, and its widths and integrated intensities have been interpreted using the Peyrard-Bishop-Dauxois (PBD) model with only one free parameter. The experiment is unique, as it gives spatial correlation along the molecule through the melting transition where other techniques cannot.
Keywords
Cite
@article{arxiv.1101.1797,
title = {The thermal denaturation of DNA studied with neutron scattering},
author = {Andrew Wildes and Nikos Theodorakopoulos and Jessica Valle Orero and Santiago Cuesta-Lopez and Jean-Luc Garden and Michel Peyrard},
journal= {arXiv preprint arXiv:1101.1797},
year = {2011}
}
Comments
accepted for publication in Physical Review Letters