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Organic Electrochemical Transistors are considered today as a key technology to interact with biological medium through their intrinsic ionic-electronic coupling. In this paper, we show how this coupling can be finely tuned (in operando)…

Signal Processing · Electrical Eng. & Systems 2021-08-31 Mahdi Ghazal , Michel Daher Mansour , Corentin Scholaert , Thomas Dargent , Yannick Coffinier , Sebastien Pecqueur , Fabien Alibart

Microelectromagnet devices, a ring trap and a matrix, were developed for the microscopic control of biological systems. The ring trap is a circular Au wire with an insulator on top. The matrix has two arrays of straight Au wires, one array…

Quantitative Methods · Quantitative Biology 2007-05-23 H. Lee , A. M. Purdon , R. M. Westervelt

Dielectric elastomers (DEs) that couple deformation and electrostatics have the potential for use in soft sensors and actuators with applications ranging from robotic, biomedical, energy, aerospace and automotive technologies. However,…

Soft Condensed Matter · Physics 2020-10-07 Matthew Grasinger , Kaushik Dayal

How cells move through the three-dimensional extracellular matrix (ECM) is of increasing interest in attempts to understand important biological processes such as cancer metastasis. Just as in motion on flat surfaces, it is expected that…

Biological Physics · Physics 2017-09-15 Yunsong Zhang , Jingchen Feng , Shay I. Heizler , Herbert Levine

We propose to use a compound of magnetic nanoparticles (20-100 nm) embedded in a flexible polymer (Polydimethylsiloxane PDMS) to filter circulating tumor cells (CTCs). The analysis of CTCs is an emerging tool for cancer biology research and…

Three-dimensional (3D) printing of bioelectronics offers a versatile platform for fabricating personalized and structurally integrated electronic systems within biological scaffolds. Biodegradable electronics, which naturally dissolve after…

We develop a microscopic biophysical model for self-organization and reshaping of artificial tissue, that is co-driven by microscopic active forces between cells and extracellular matrix (ECM), and macroscopic forces that develop within the…

Biological Physics · Physics 2020-11-18 J. P. Hague , P. W. Mieczkowski , C. O'Rourke , A. J. Loughlin , J. B. Phillips

Using interplay between surface plasmons and metamaterials, we propose a new technique for novel metamaterial designs. We show that surface plasmons existing on thin metal surfaces can be used to "drive" non-resonant structures in their…

Optics · Physics 2011-04-12 Durdu O. Guney , Thomas Koschny , Costas M. Soukoulis

We report an acoustic approach to measure the elastic properties of an extracellular matrix (ECM). This approach uses a short range evanescent waves to inject sound into the test material over a short distance using an electroded quartz…

Biological Physics · Physics 2018-01-03 Jenny Overton , Arthur Kissin , William Bains , Adrian Stevenson

This essay is a recapitulation of an earlier Kramers-Kronig analysis of biological tissue, published in 2010, "Kramers-Kronig analysis of biological skin". The intent is to both complement and bolster the antecedent analysis by furnishing…

Tissues and Organs · Quantitative Biology 2011-12-22 Luisiana X. Cundin

Bicontinuous microstructures are essential to the function of diverse natural and synthetic systems. Their synthesis has been based on two approaches: arrested phase separation or self-assembly of block copolymers. The former is attractive…

Computational modelling offers a cost-effective and time-efficient alternative to experimental studies in biomedical engineering. In cardiac electro-mechanics, finite element method (FEM)-based simulations provide valuable insights into…

Computational Engineering, Finance, and Science · Computer Science 2025-08-20 Tan Tran , Denisa Martonova , Sigrid Leyendecker

Extracellular matrix (ECM) remodeling is central to a wide variety of healthy and diseased tissue processes. Unfortunately, predicting ECM remodeling under various chemical and mechanical conditions has proven to be excessively challenging,…

Molecular Networks · Quantitative Biology 2026-05-26 Hasi Hays , William J. Richardson

Active metamaterials are a type of metamaterial with tunable properties enabled by structural reconfigurations. Existing active metamaterials often achieve only a limited number of structural reconfigurations upon the application of an…

Applied Physics · Physics 2025-01-23 Jay Sim , Shuai Wu , Sarah Hwang , Lu Lu , Ruike Renee Zhao

Neuromorphic computing and engineering has been the focus of intense research efforts that have been intensified recently by the mutation of Information and Communication Technologies (ICT). In fact, new computing solutions and new hardware…

Applied Physics · Physics 2018-10-09 Sebastien Pecqueur , Dominique Vuillaume , Fabien Alibart

Colloidal magnetic particles embedded in an elastic polymer matrix constitute a smart material called ferrogel. It responds to an applied external magnetic field by changes in elastic properties, which can be exploited for various…

Soft Condensed Matter · Physics 2016-10-07 Peet Cremer , Hartmut Löwen , Andreas M. Menzel

Based on bottom-up assembly of highly variable neural cells units, the nervous system can reach unequalled level of performances with respect to standard materials and devices used in microelectronic. Reproducing these basic concepts in…

Extrusion 3D-printing of biopolymers and natural fiber-based biocomposites allows for the fabrication of complex structures, ranging from gels for healthcare applications to eco-friendly structural materials. However, traditional polymer…

Biological Physics · Physics 2024-11-26 Israel Kellersztein , Daniel Tish , John Pederson , Martin Bechthold , Chiara Daraio

Inspired by the cellular design of plant tissue, we present a new approach to make versatile, tough, highly water-swelling composites. We embed highly swelling hydrogel particles inside tough, water-permeable, elastomeric matrices. The…

Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly nonlinear mechanical properties. While the linear elasticity of the matrix can significantly impact cell mechanics and functionality, it remains…