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Large language models, such as GPT-4 and Med-PaLM, have shown impressive performance on clinical tasks; however, they require access to compute, are closed-source, and cannot be deployed on device. Mid-size models such as BioGPT-large,…

Large Language Models (LLMs) often produce explanations that do not faithfully reflect the factors driving their predictions. In healthcare settings, such unfaithfulness is especially problematic: explanations that omit salient clinical…

Computation and Language · Computer Science 2025-11-04 Teague McMillan , Gabriele Dominici , Martin Gjoreski , Marc Langheinrich

Large language models (LLMs) have demonstrated immense capabilities in understanding textual data and are increasingly being adopted to help researchers accelerate scientific discovery through knowledge extraction (information retrieval),…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Robinson Umeike , Neil Getty , Fangfang Xia , Rick Stevens

As Large Language Models (LLMs) become widely accessible, a detailed understanding of their knowledge within specific domains becomes necessary for successful real world use. This is particularly critical in the domains of medicine and…

Large language models (LLMs) have become the foundation of many applications, leveraging their extensive capabilities in processing and understanding natural language. While many open-source LLMs have been released with technical reports,…

The rapid advancement of large language models (LLMs) has significantly impacted various domains, including healthcare and biomedicine. However, the phenomenon of hallucination, where LLMs generate outputs that deviate from factual accuracy…

Computation and Language · Computer Science 2024-08-27 Duy Khoa Pham , Bao Quoc Vo

Multimodal Large Language Model (MLLM) has recently garnered attention as a prominent research focus. By harnessing powerful LLM, it facilitates a transition of conversational generative AI from unimodal text to performing multimodal tasks.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Xuechen Guo , Wenhao Chai , Shi-Yan Li , Gaoang Wang

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Computation and Language · Computer Science 2023-09-08 Supun Manathunga , Isuru Hettigoda

Large language models (LLMs) have shown remarkable performance on many tasks in different domains. However, their performance in closed-book biomedical machine reading comprehension (MRC) has not been evaluated in depth. In this work, we…

Computation and Language · Computer Science 2024-10-28 Shubham Vatsal , Ayush Singh

Retriever Augmented Generation (RAG) systems have become pivotal in enhancing the capabilities of language models by incorporating external knowledge retrieval mechanisms. However, a significant challenge in deploying these systems in…

Computation and Language · Computer Science 2024-06-06 Masha Belyi , Robert Friel , Shuai Shao , Atindriyo Sanyal

The deployment of Large Language Models (LLMs) in mental health counseling faces the dual challenges of hallucinations and lack of empathy. While the former may be mitigated by RAG (retrieval-augmented generation) by anchoring answers in…

Computation and Language · Computer Science 2026-01-06 Md Abdullah Al Kafi , Raka Moni , Sumit Kumar Banshal

Large language models (LLMs) are increasingly recognized as valuable tools across the medical environment, supporting clinical, research, and administrative workflows. However, strict privacy and network security regulations in hospital…

Computation and Language · Computer Science 2026-01-09 Seokhwan Ko , Donghyeon Lee , Jaewoo Chun , Hyungsoo Han , Junghwan Cho

Large Language Models (LLMs) and AI assistants driven by these models are experiencing exponential growth in usage among both expert and amateur users. In this work, we focus on evaluating the reliability of current LLMs as science…

Computation and Language · Computer Science 2024-09-24 Prasoon Bajpai , Niladri Chatterjee , Subhabrata Dutta , Tanmoy Chakraborty

Large language models (LLMs) have demonstrated powerful text generation capabilities, bringing unprecedented innovation to the healthcare field. While LLMs hold immense promise for applications in healthcare, applying them to real clinical…

Computation and Language · Computer Science 2023-10-16 Rui Yang , Edison Marrese-Taylor , Yuhe Ke , Lechao Cheng , Qingyu Chen , Irene Li

Large Language Models (LLMs) have introduced a new era of proficiency in comprehending complex healthcare and biomedical topics. However, there is a noticeable lack of models in languages other than English and models that can interpret…

Computer Vision and Pattern Recognition · Computer Science 2023-11-02 Junling Liu , Ziming Wang , Qichen Ye , Dading Chong , Peilin Zhou , Yining Hua

Large language models (LLMs) achieve strong performance across many natural language processing tasks, yet their decision processes remain difficult to interpret. This lack of transparency creates challenges for trust, debugging, and…

Computation and Language · Computer Science 2026-04-20 Venkata Abhinandan Kancharla

Large language models (LLMs) have demonstrated remarkable performance on question-answering (QA) tasks because of their superior capabilities in natural language understanding and generation. However, LLM-based QA struggles with complex QA…

Computation and Language · Computer Science 2025-09-23 Chuangtao Ma , Yongrui Chen , Tianxing Wu , Arijit Khan , Haofen Wang

Clinicians often need to retrieve patient-specific information from electronic health records (EHRs), a task that is time-consuming and error-prone. We present a locally deployable Clinical Contextual Question Answering (CCQA) framework…

Computation and Language · Computer Science 2026-03-30 Mikko Saukkoriipi , Nicole Hernandez , Jaakko Sahlsten , Kimmo Kaski , Otso Arponen

Large language models (LLMs) have rapidly advanced natural language processing, driving significant breakthroughs in tasks such as text generation, machine translation, and domain-specific reasoning. The field now faces a critical dilemma…

Computation and Language · Computer Science 2025-10-15 Jiya Manchanda , Laura Boettcher , Matheus Westphalen , Jasser Jasser

Medical reasoning in large language models (LLMs) aims to emulate clinicians' diagnostic thinking, but current benchmarks such as MedQA-USMLE, MedMCQA, and PubMedQA often mix reasoning with factual recall. We address this by separating 11…