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The development of effective machine learning methodologies for enhancing the efficiency and accuracy of clinical systems is crucial. Despite significant research efforts, managing a plethora of diversified clinical tasks and adapting to…

Computation and Language · Computer Science 2024-06-19 Yujiang Wu , Hongjian Song , Jiawen Zhang , Xumeng Wen , Shun Zheng , Jiang Bian

Large language model (LLM)-based agents have demonstrated remarkable capabilities in addressing complex tasks, thereby enabling more advanced information retrieval and supporting deeper, more sophisticated human information-seeking…

Artificial Intelligence · Computer Science 2025-11-11 Yuyang Zhao , Wentao Shi , Fuli Feng , Xiangnan He

We introduce AttriGen, a novel framework for automated, fine-grained multi-attribute annotation in computer vision, with a particular focus on cell microscopy where multi-attribute classification remains underrepresented compared to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Walid Houmaidi , Youssef Sabiri , Fatima Zahra Iguenfer , Amine Abouaomar

Existing change detection methods often lack the versatility to handle diverse real-world queries and the intelligence for comprehensive analysis. This paper presents a general agent framework, integrating Large Language Models (LLM) with…

Artificial Intelligence · Computer Science 2026-01-08 Zixuan Xiao , Jun Ma

Large Language Models (LLMs) increasingly act as function-call agents that invoke external tools to tackle tasks beyond their static knowledge. However, they typically invoke tools one at a time without a global view of task structure. As…

Artificial Intelligence · Computer Science 2026-05-22 Yan Jiang , Hao Zhou , Lizhong GU , Tianlong Li , Ruinan Jin , Wanqi Zhou , Ai Han

Rare diseases, despite their low individual incidence, collectively impact around 300 million people worldwide due to the vast number of diseases. The involvement of multiple organs and systems, and the shortage of specialized doctors with…

Computation and Language · Computer Science 2025-11-11 Xuanzhong Chen , Ye Jin , Xiaohao Mao , Lun Wang , Shuyang Zhang , Ting Chen

Cell counting remains a fundamental yet challenging task in medical and biological research due to the diverse morphology of cells, their dense distribution, and variations in image quality. We present DLA-Count, a breakthrough approach to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Yuqing Yan , Yirui Wu

The development of single-cell and spatial transcriptomics has revolutionized our capacity to investigate cellular properties, functions, and interactions in both cellular and spatial contexts. However, the analysis of single-cell and…

Genomics · Quantitative Biology 2024-12-09 Shuang Ge , Shuqing Sun , Huan Xu , Qiang Cheng , Zhixiang Ren

The quality of instruction data directly affects the performance of fine-tuned Large Language Models (LLMs). Previously, \cite{li2023one} proposed \texttt{NUGGETS}, which identifies and selects high-quality quality data from a large dataset…

Computation and Language · Computer Science 2024-12-16 Shiwen Ni , Haihong Wu , Di Yang , Qiang Qu , Hamid Alinejad-Rokny , Min Yang

This paper explores the use of large language models (LLMs) for annotating document utility in training retrieval and retrieval-augmented generation (RAG) systems, aiming to reduce dependence on costly human annotations. We address the gap…

Information Retrieval · Computer Science 2025-10-10 Hengran Zhang , Minghao Tang , Keping Bi , Jiafeng Guo , Shihao Liu , Daiting Shi , Dawei Yin , Xueqi Cheng

Large language models (LLMs) and agent techniques have brought a fundamental shift in the functionality and development paradigm of data analysis tasks (a.k.a LLM/Agent-as-Data-Analyst), demonstrating substantial impact across both academia…

The recent advance in Large Language Models (LLMs) has shaped a new paradigm of AI agents, i.e., LLM-based agents. Compared to standalone LLMs, LLM-based agents substantially extend the versatility and expertise of LLMs by enhancing LLMs…

Software Engineering · Computer Science 2025-12-04 Junwei Liu , Kaixin Wang , Yixuan Chen , Xin Peng , Zhenpeng Chen , Lingming Zhang , Yiling Lou

Automated single-cell annotation is difficult when the most abundant genes are not the most discriminative ones, or when a target state is poorly covered by a fixed reference atlas. GPTCelltype-style one-shot prompting allows large language…

Quantitative Methods · Quantitative Biology 2026-05-08 Yehui Yang , Zelin Zang , Xienan Zheng , Yuzhe Jia , Changxi Chi , Jingbo Zhou , Chang Yu , Jinlin Wu , Fuji Yang , Jiebo Luo , Zhen Lei , Stan Z. Li

The structural properties of naturally arising social graphs are extensively studied to understand their evolution. Prior approaches for modeling network dynamics typically rely on rule-based models, which lack realism and generalizability,…

Computation and Language · Computer Science 2025-01-07 Jiarui Ji , Runlin Lei , Jialing Bi , Zhewei Wei , Xu Chen , Yankai Lin , Xuchen Pan , Yaliang Li , Bolin Ding

New lesion segmentation is essential to estimate the disease progression and therapeutic effects during multiple sclerosis (MS) clinical treatments. However, the expensive data acquisition and expert annotation restrict the feasibility of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-18 Yicheng Wu , Zhonghua Wu , Hengcan Shi , Bjoern Picker , Winston Chong , Jianfei Cai

Student simulation in online education is important to address dynamic learning behaviors of students with diverse backgrounds. Existing simulation models based on deep learning usually need massive training data, lacking prior knowledge in…

Computers and Society · Computer Science 2024-04-12 Songlin Xu , Xinyu Zhang , Lianhui Qin

We present BioRAGent, an interactive web-based retrieval-augmented generation (RAG) system for biomedical question answering. The system uses large language models (LLMs) for query expansion, snippet extraction, and answer generation while…

Computation and Language · Computer Science 2024-12-18 Samy Ateia , Udo Kruschwitz

Vision-Language Models (VLMs) show promise in medical diagnosis, yet suffer from reasoning detachment, where linguistically fluent explanations drift from verifiable image evidence, undermining clinical trust. Recent multi-agent frameworks…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Qianhan Feng , Zhongzhen Huang , Yakun Zhu , Xiaofan Zhang , Qi Dou

The advent of single-cell multi-omics technologies has enabled the simultaneous profiling of diverse omics layers within individual cells. Integrating such multimodal data provides unprecedented insights into cellular identity, regulatory…

Cell Behavior · Quantitative Biology 2025-06-27 Zhen Yuan , Shaoqing Jiao , Yihang Xiao , Jiajie Peng

Open large language models (LLMs) have significantly advanced the field of natural language processing, showcasing impressive performance across various tasks.Despite the significant advancements in LLMs, their effective operation still…

Computation and Language · Computer Science 2025-04-16 Xuechen Liang , Yangfan He , Meiling Tao , Yinghui Xia , Jianhui Wang , Tianyu Shi , Jun Wang , JingSong Yang