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Large Language Models (LLMs) have been successful in mathematical reasoning tasks such as formal theorem proving when integrated with interactive proof assistants like Lean. Existing approaches involve training or fine-tuning an LLM on a…

Machine Learning · Computer Science 2025-03-07 Adarsh Kumarappan , Mo Tiwari , Peiyang Song , Robert Joseph George , Chaowei Xiao , Anima Anandkumar

The advancement of artificial intelligence (AI) for organ segmentation and tumor detection is propelled by the growing availability of computed tomography (CT) datasets with detailed, per-voxel annotations. However, these AI models often…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Jie Liu , Yixiao Zhang , Kang Wang , Mehmet Can Yavuz , Xiaoxi Chen , Yixuan Yuan , Haoliang Li , Yang Yang , Alan Yuille , Yucheng Tang , Zongwei Zhou

Large Language Models (LLMs) have shown promising performance in time series modeling tasks, but do they truly understand time series data? While multiple benchmarks have been proposed to answer this fundamental question, most are manually…

Artificial Intelligence · Computer Science 2026-04-15 Malgorzata Gwiazda , Yifu Cai , Mononito Goswami , Arjun Choudhry , Artur Dubrawski

Large Language Models (LLMs) have enabled intelligent agents that autonomously interact with environments and invoke external tools. Recently, agent-based software repair has drawn wide attention, as repair agents can localize bugs,…

Software Engineering · Computer Science 2026-05-26 Quanjun Zhang , Chengyu Gao , Yu Han , Ye Shang , Chunrong Fang , Zhenyu Chen , Liang Xiao

Image tagging, a fundamental vision task, traditionally relies on human-annotated datasets to train multi-label classifiers, which incurs significant labor and costs. While Multimodal Large Language Models (MLLMs) offer promising potential…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Ming-Kun Xie , Jia-Hao Xiao , Zhiqiang Kou , Zhongnian Li , Gang Niu , Masashi Sugiyama

Recent studies have demonstrated the feasibility of modeling single-cell data as natural languages and the potential of leveraging powerful large language models (LLMs) for understanding cell biology. However, a comprehensive evaluation of…

Quantitative Methods · Quantitative Biology 2025-05-14 Fan Zhang , Tianyu Liu , Zhihong Zhu , Hao Wu , Haixin Wang , Donghao Zhou , Yefeng Zheng , Kun Wang , Xian Wu , Pheng-Ann Heng

Cell type annotation is a fundamental step in the analysis of single-cell RNA sequencing (scRNA-seq) data. In practice, human experts often rely on the structure revealed by principal component analysis (PCA) followed by $k$-nearest…

Genomics · Quantitative Biology 2026-02-10 Tianxiang Hu , Chenyi Zhou , Jiaxiang Liu , Jiongxin Wang , Ruizhe Chen , Haoxiang Xia , Gaoang Wang , Jian Wu , Zuozhu Liu

Large Language Models (LLMs) are transforming artificial intelligence, evolving into task-oriented systems capable of autonomous planning and execution. One of the primary applications of LLMs is conversational AI systems, which must…

Computation and Language · Computer Science 2025-01-22 Elad Levi , Ilan Kadar

Large-scale datasets with high-quality labels are desired for training accurate deep learning models. However, due to the annotation cost, datasets in medical imaging are often either partially-labeled or small. For example, DeepLesion is…

Computer Vision and Pattern Recognition · Computer Science 2021-01-05 Ke Yan , Jinzheng Cai , Youjing Zheng , Adam P. Harrison , Dakai Jin , Youbao Tang , Yuxing Tang , Lingyun Huang , Jing Xiao , Le Lu

Textual data annotation, the process of labeling or tagging text with relevant information, is typically costly, time-consuming, and labor-intensive. While large language models (LLMs) have demonstrated their potential as direct…

Computation and Language · Computer Science 2025-08-12 Yu-Min Tseng , Wei-Lin Chen , Chung-Chi Chen , Hsin-Hsi Chen

Emerging 6G networks rely on complex cross-layer optimization, yet manually translating high-level intents into mathematical formulations remains a bottleneck. While Large Language Models (LLMs) offer promise, monolithic approaches often…

Artificial Intelligence · Computer Science 2026-01-28 Haoyun Li , Ming Xiao , Kezhi Wang , Robert Schober , Dong In Kim , Yong Liang Guan

Cells are the fundamental unit of biological organization, and identifying them in imaging data - cell segmentation - is a critical task for various cellular imaging experiments. While deep learning methods have led to substantial progress…

Clinical decision-making is inherently complex and fast-paced, particularly in emergency departments (EDs) where critical, rapid and high-stakes decisions are made. Clinical Decision Rules (CDRs) are standardized evidence-based tools that…

We present a novel method for automated identification of putative cell types from single-cell RNA-seq (scRNA-seq) data. By iteratively applying a machine learning approach to an initial clustering of gene expression profiles of a given set…

Quantitative Methods · Quantitative Biology 2020-04-22 Zhichao Miao , Pablo Moreno , Ni Huang , Irene Papatheodorou , Alvis Brazma , Sarah A Teichmann

Scientific research increasingly relies on specialized computational tools, yet effectively utilizing these tools demands substantial domain expertise. While Large Language Models (LLMs) show promise in tool automation, they struggle to…

Artificial Intelligence · Computer Science 2025-07-29 Keyan Ding , Jing Yu , Junjie Huang , Yuchen Yang , Qiang Zhang , Huajun Chen

Document Question Answering (DocQA) is a very common task. Existing methods using Large Language Models (LLMs) or Large Vision Language Models (LVLMs) and Retrieval Augmented Generation (RAG) often prioritize information from a single…

Machine Learning · Computer Science 2025-03-19 Siwei Han , Peng Xia , Ruiyi Zhang , Tong Sun , Yun Li , Hongtu Zhu , Huaxiu Yao

Organic solar cells (OSCs) hold great promise for sustainable energy, but discovering high-performance materials is time-consuming and costly. Existing molecular generation methods can aid the design of OSC molecules, but they are mostly…

Computational Engineering, Finance, and Science · Computer Science 2026-02-05 Zhaolin Hu , Zhiliang Wu , Hehe Fan , Yi Yang

In the current digital era, the rapid spread of misinformation on online platforms presents significant challenges to societal well-being, public trust, and democratic processes, influencing critical decision making and public opinion. To…

Computation and Language · Computer Science 2024-05-06 Xinyi Li , Yongfeng Zhang , Edward C. Malthouse

Scientific data visualization plays a crucial role in research by enabling the direct display of complex information and assisting researchers in identifying implicit patterns. Despite its importance, the use of Large Language Models (LLMs)…

Computation and Language · Computer Science 2024-03-20 Zhiyu Yang , Zihan Zhou , Shuo Wang , Xin Cong , Xu Han , Yukun Yan , Zhenghao Liu , Zhixing Tan , Pengyuan Liu , Dong Yu , Zhiyuan Liu , Xiaodong Shi , Maosong Sun

The discovery of novel small molecule drugs remains a critical scientific challenge with far-reaching implications for treating diseases and advancing human health. Traditional drug development--especially for small molecule…

Biomolecules · Quantitative Biology 2025-04-01 Bowen Gao , Yanwen Huang , Yiqiao Liu , Wenxuan Xie , Wei-Ying Ma , Ya-Qin Zhang , Yanyan Lan
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