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The Segment Anything Model (SAM) has revolutionized interactive segmentation through spatial prompting. While existing work primarily focuses on automating prompts in various settings, real-world annotation workflows involve iterative…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Prithwijit Chowdhury , Mohit Prabhushankar , Ghassan AlRegib

AI-assisted nuclei segmentation in histopathological images is a crucial task in the diagnosis and treatment of cancer diseases. It decreases the time required to manually screen microscopic tissue images and can resolve the conflict…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Hesham Ali , Idriss Tondji , Mennatullah Siam

The Segment Anything Model (SAM) is a powerful foundation model that introduced revolutionary advancements in natural image segmentation. However, its performance remains sub-optimal when delineating the intricate structure of biomedical…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Xiangru Li , Yifei Zhang , Liang Zhao

Segmentation models such as Segment Anything Model (SAM) and SAM2 achieve strong prompt-driven zero-shot performance. However, their training on natural images limits domain transfer to medical data. Consequently, accurate segmentation…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Tal Grossman , Noa Cahan , Lev Ayzenberg , Hayit Greenspan

The Segment Anything Model (SAM) exhibits remarkable versatility and zero-shot learning abilities, owing largely to its extensive training data (SA-1B). Recognizing SAM's dependency on manual guidance given its category-agnostic nature, we…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Xiyu Qi , Yifan Wu , Yongqiang Mao , Wenhui Zhang , Yidan Zhang

Semantic segmentation is a crucial task in medical imaging. Although supervised learning techniques have proven to be effective in performing this task, they heavily depend on large amounts of annotated training data. The recently…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Ron Keuth , Lasse Hansen , Maren Balks , Ronja Jäger , Anne-Nele Schröder , Ludger Tüshaus , Mattias Heinrich

Purpose: Endoscopic surgical environments present challenges for dissection zone segmentation due to unclear boundaries between tissue types, leading to segmentation errors where models misidentify or overlook edges. This study aims to…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Mengya Xu , Wenjin Mo , Guankun Wang , Huxin Gao , An Wang , Zhen Li , Xiaoxiao Yang , Hongliang Ren

The Segment Anything Model (SAM) has exhibited outstanding performance in various image segmentation tasks. Despite being trained with over a billion masks, SAM faces challenges in mask prediction quality in numerous scenarios, especially…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Zhaozhi Xie , Bochen Guan , Weihao Jiang , Muyang Yi , Yue Ding , Hongtao Lu , Lei Zhang

Segmentation is vital for ophthalmology image analysis. But its various modal images hinder most of the existing segmentation algorithms applications, as they rely on training based on a large number of labels or hold weak generalization…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Zhongxi Qiu , Yan Hu , Heng Li , Jiang Liu

Promptable foundation models, particularly Segment Anything Model (SAM), have emerged as a promising alternative to the traditional task-specific supervised learning for image segmentation. However, many evaluation studies have found that…

Computer Vision and Pattern Recognition · Computer Science 2023-10-27 Rachana Sathish , Rahul Venkataramani , K S Shriram , Prasad Sudhakar

Segment Anything Model 2 (SAM 2), a prompt-driven foundation model extending SAM to both image and video domains, has shown superior zero-shot performance compared to its predecessor. Building on SAM's success in medical image segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-06 Bin Xie , Hao Tang , Yan Yan , Gady Agam

The Segment Anything Model (SAM) excels at general image segmentation but has limited ability to understand natural language, which restricts its direct application in Referring Expression Segmentation (RES). Toward this end, we propose…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Wei Tang , Xuejing Liu , Yanpeng Sun , Zechao Li

Nuclear segmentation in histology images is a challenging task due to significant variations in the shape and appearance of nuclei. One of the main hurdles in nuclear instance segmentation is overlapping nuclei where a smart algorithm is…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Navid Alemi Koohbanani , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

Deep learning-based medical image segmentation models often suffer from domain shift, where the models trained on a source domain do not generalize well to other unseen domains. As a prompt-driven foundation model with powerful…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Yifan Gao , Wei Xia , Dingdu Hu , Wenkui Wang , Xin Gao

Training segmentation models for medical images continues to be challenging due to the limited availability of data annotations. Segment Anything Model (SAM) is a foundation model that is intended to segment user-defined objects of interest…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Maciej A. Mazurowski , Haoyu Dong , Hanxue Gu , Jichen Yang , Nicholas Konz , Yixin Zhang

Powered by massive curated training data, Segment Anything Model (SAM) has demonstrated its impressive generalization capabilities in open-world scenarios with the guidance of prompts. However, the vanilla SAM is class agnostic and heavily…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Duojun Huang , Xinyu Xiong , Jie Ma , Jichang Li , Zequn Jie , Lin Ma , Guanbin Li

Medical image segmentation has immense clinical applicability but remains a challenge despite advancements in deep learning. The Segment Anything Model (SAM) exhibits potential in this field, yet the requirement for expertise intervention…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Yinsong Xu , Jiaqi Tang , Aidong Men , Qingchao Chen

Single-point annotation is increasingly prominent in visual tasks for labeling cost reduction. However, it challenges tasks requiring high precision, such as the point-prompted instance segmentation (PPIS) task, which aims to estimate…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Zhaoyang Wei , Xumeng Han , Xuehui Yu , Xue Yang , Guorong Li , Zhenjun Han , Jianbin Jiao

This work proposes a novel approach beyond supervised learning for effective pathological image analysis, addressing the challenge of limited robust labeled data. Pathological diagnosis of diseases like cancer has conventionally relied on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Joonhyeon Song , Seohwan Yun , Seongho Yoon , Joohyeok Kim , Sangmin Lee

Foundation models have taken over natural language processing and image generation domains due to the flexibility of prompting. With the recent introduction of the Segment Anything Model (SAM), this prompt-driven paradigm has entered image…

Image and Video Processing · Electrical Eng. & Systems 2023-04-13 Saikat Roy , Tassilo Wald , Gregor Koehler , Maximilian R. Rokuss , Nico Disch , Julius Holzschuh , David Zimmerer , Klaus H. Maier-Hein
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