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The conditional generation of proteins with desired functions is a key goal for generative models. Existing methods based on prompting of protein language models (PLMs) can generate proteins conditioned on a target functionality, such as a…

Biomolecules · Quantitative Biology 2025-06-13 Jason Yang , Aadyot Bhatnagar , Jeffrey A. Ruffolo , Ali Madani

In recent years, the development of diffusion models has led to significant progress in image and video generation tasks, with pre-trained models like the Stable Diffusion series playing a crucial role. Inspired by model pruning which…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Teng Hu , Jiangning Zhang , Ran Yi , Hongrui Huang , Yabiao Wang , Lizhuang Ma

Low-Rank Adaptation (LoRA) lowers the computational and memory overhead of fine-tuning large models by updating a low-dimensional subspace of the pre-trained weight matrix. Albeit efficient, LoRA exhibits suboptimal convergence and…

Machine Learning · Computer Science 2026-02-25 Yilang Zhang , Bingcong Li , Georgios B. Giannakis

Adapting LLMs to specific stylistic characteristics, like brand voice or authorial tones, is crucial for enterprise communication but challenging to achieve from corpora which lacks instruction-response formatting without compromising…

Computation and Language · Computer Science 2025-07-25 Pritika Ramu , Apoorv Saxena , Meghanath M Y , Varsha Sankar , Debraj Basu

Fine-tuning large-scale pre-trained models is prohibitively expensive in terms of computation and memory costs. Low-Rank Adaptation (LoRA), a popular Parameter-Efficient Fine-Tuning (PEFT) method, offers an efficient solution by optimizing…

Machine Learning · Computer Science 2025-05-27 Tao Li , Zhengbao He , Yujun Li , Yasheng Wang , Lifeng Shang , Xiaolin Huang

Fine-tuning pre-trained large language models in a parameter-efficient manner is widely studied for its effectiveness and efficiency. LoRA is one of the most widely used methods, which assumes that the optimization process is essentially…

Computation and Language · Computer Science 2024-12-16 Changqun Li , Chaofan Ding , Kexin Luan , Xinhan Di

Large Language Models (LLMs) offer a promising basis for creating agents that can tackle complex tasks through iterative environmental interaction. Existing methods either require these agents to mimic expert-provided trajectories or rely…

Computation and Language · Computer Science 2024-12-02 Dihong Gong , Pu Lu , Zelong Wang , Meng Zhou , Xiuqiang He

Low-Rank Adaptation (LoRA) is one of the most widely used techniques for fine-tuning large language models (LLMs). By introducing a small number of trainable low-rank weight matrices, LoRA substantially reduces the number of parameters that…

Machine Learning · Computer Science 2025-07-15 Seokmin Ko

This paper introduces diffusion protein language model (DPLM), a versatile protein language model that demonstrates strong generative and predictive capabilities for protein sequences. We first pre-train scalable DPLMs from…

Machine Learning · Computer Science 2024-10-17 Xinyou Wang , Zaixiang Zheng , Fei Ye , Dongyu Xue , Shujian Huang , Quanquan Gu

Can large language models (LLMs) generate continuous numerical features that improve reinforcement learning (RL) trading agents? We build a modular pipeline where a frozen LLM serves as a stateless feature extractor, transforming…

Computation and Language · Computer Science 2026-04-14 Zhengzhe Yang

The development of generative language models that can create long and coherent textual outputs via autoregression has lead to a proliferation of uses and a corresponding sweep of analyses as researches work to determine the limitations of…

Computation and Language · Computer Science 2024-12-11 Reid McIlroy-Young , Katrina Brown , Conlan Olson , Linjun Zhang , Cynthia Dwork

Large language models (LLMs) have demonstrated impressive capabilities in natural language generation. However, their output quality can be inconsistent, posing challenges for generating natural language from logical forms (LFs). This task…

Computation and Language · Computer Science 2023-09-22 Levon Haroutunian , Zhuang Li , Lucian Galescu , Philip Cohen , Raj Tumuluri , Gholamreza Haffari

We introduce Options LLM (OLLM), a simple, general method that replaces the single next-token prediction of standard LLMs with a \textit{set of learned options} for the next token, indexed by a discrete latent variable. Instead of relying…

Artificial Intelligence · Computer Science 2026-04-22 Shashank Sharma , Janina Hoffmann , Vinay Namboodiri

Modern wireless networks must adapt to dynamic conditions while efficiently managing diverse service demands. Traditional deep reinforcement learning (DRL) struggles in these environments, as scattered and evolving feedback makes optimal…

Machine Learning · Computer Science 2025-06-03 Fatemeh Lotfi , Hossein Rajoli , Fatemeh Afghah

Large language model (LLM) agents struggle to autonomously evolve coordination strategies in dynamic environments, largely because coarse global outcomes obscure the causal signals needed for local policy refinement. We identify this…

Computation and Language · Computer Science 2026-04-02 Huaiyuan Yao , Longchao Da , Xiaoou Liu , Charles Fleming , Tianlong Chen , Hua Wei

We present Generalized LoRA (GLoRA), an advanced approach for universal parameter-efficient fine-tuning tasks. Enhancing Low-Rank Adaptation (LoRA), GLoRA employs a generalized prompt module to optimize pre-trained model weights and adjust…

Machine Learning · Computer Science 2023-10-17 Arnav Chavan , Zhuang Liu , Deepak Gupta , Eric Xing , Zhiqiang Shen

Low-Rank Adaptation (LoRA) is a widely adopted parameter-efficient fine-tuning (PEFT) method validated across NLP and CV domains. However, LoRA faces an inherent low-rank bottleneck: narrowing its performance gap with full finetuning…

Machine Learning · Computer Science 2025-12-03 Haonan Dong , Wenhao Zhu , Guojie Song , Liang Wang

Large language models have achieved remarkable success under the autoregressive paradigm, yet high-quality text generation need not be tied to a fixed left-to-right order. Existing alternatives still struggle to jointly achieve generation…

Computation and Language · Computer Science 2026-05-08 Hongcan Guo , Qinyu Zhao , Yian Zhao , Shen Nie , Rui Zhu , Qiushan Guo , Feng Wang , Tao Yang , Hengshuang Zhao , Guoqiang Wei , Yan Zeng

Fine-tuning large-scale pre-trained models is inherently a resource-intensive task. While it can enhance the capabilities of the model, it also incurs substantial computational costs, posing challenges to the practical application of…

Computation and Language · Computer Science 2024-06-27 Yulong Mao , Kaiyu Huang , Changhao Guan , Ganglin Bao , Fengran Mo , Jinan Xu

We propose a neural language modeling system based on low-rank adaptation (LoRA) for speech recognition output rescoring. Although pretrained language models (LMs) like BERT have shown superior performance in second-pass rescoring, the high…

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