English
Related papers

Related papers: Predicting Targeted Therapy Resistance in Non-Smal…

200 papers

Lung cancer remains one of the leading causes of morbidity and mortality worldwide, making early diagnosis critical for improving therapeutic outcomes and patient prognosis. Computer-aided diagnosis systems, which analyze computed…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Guohui Cai , Ying Cai , Zeyu Zhang , Yuanzhouhan Cao , Lin Wu , Daji Ergu , Zhinbin Liao , Yang Zhao

Lung cancer remains one of the leading causes of cancer-related mortality, yet most survival models rely only on baseline factors and overlook posttreatment variables that reflect disease progression. To address this gap, we applied Cox…

Applications · Statistics 2025-10-03 Varun Vishwanathan Nair , Victor Miranda Soberanis

Survival prediction is a crucial task associated with cancer diagnosis and treatment planning. This paper presents a novel approach to survival prediction by harnessing comprehensive information from CT and PET scans, along with associated…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Aiman Farooq , Deepak Mishra , Santanu Chaudhury

Lung cancer is one of the deadliest diseases and the leading cause of illness and death. Since lung cancer cannot predicted at premature stage, it able to only be discovered more broadly once it has spread to other lung parts. The risk…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 V S Priya Sumitha , V. Keerthika , A. Geetha

Formulating tumor models that predict growth under therapy is vital for improving patient-specific treatment plans. In this context, we present our recent work on simulating non-small-scale cell lung cancer (NSCLC) in a simple,…

Prognostication for lung cancer, a leading cause of mortality, remains a complex task, as it needs to quantify the associations of risk factors and health events spanning a patient's entire life. One challenge is that an individual's…

Machine Learning · Statistics 2025-08-28 Stephen Salerno , Yi Li

To enable personalized cancer treatment, machine learning models have been developed to predict drug response as a function of tumor and drug features. However, most algorithm development efforts have relied on cross validation within a…

Colorectal cancer is one of the most common and lethal cancers and colorectal cancer liver metastases (CRLM) is the major cause of death in patients with colorectal cancer. Multifocality occurs frequently in CRLM, but is relatively…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Jianan Chen , Helen M. C. Cheung , Laurent Milot , Anne L. Martel

Ovarian cancer is the most lethal gynecologic malignancy: around 60% of patients are diagnosed at an advanced stage, with an associated 5-year survival rate of about 30%. Early identification of non-responders to neoadjuvant chemotherapy…

With an estimated 160,000 deaths in 2018, lung cancer is the most common cause of cancer death in the United States. Lung cancer CT screening has been shown to reduce mortality by up to 40% and is now included in US screening guidelines.…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Daniel Korat

Febrile neutropenia (FN) has been associated with high mortality, especially among adults with cancer. Understanding the patient and provider level heterogeneity in FN hospital admissions has potential to inform personalized interventions…

Quantitative Methods · Quantitative Biology 2019-05-28 Xinsong Du , Jae Min , Mattia Prosperi , Rohit Bishnoi , Dominick J. Lemas , Chintan P. Shah

In non-small cell lung cancer (NSCLC) clinical trials, tumor burden (TB) is a key longitudinal biomarker for assessing treatment effects. Typically, standard-of-care (SOC) therapies and some novel interventions initially decrease TB;…

Methodology · Statistics 2025-07-28 Yixiang Qu , Ethan M. Alt , Weibin Zhong , Jeen Liu , Chenguang Wang , Joseph G. Ibrahim

Lung cancer has the highest rate of cancer-caused deaths, and early-stage diagnosis could increase the survival rate. Lung nodules are common indicators of lung cancer, making their detection crucial. Various lung nodule detection models…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Saeed Shakuri , Alireza Rezvanian

Lung cancer (LC) remains the primary cause of cancer-related mortality, largely due to late-stage diagnoses. Effective strategies for early detection are therefore of paramount importance. In recent years, machine learning (ML) has…

This paper primarily addresses a dataset relating to cellular, chemical and physical conditions of patients gathered at the time they are operated upon to remove colorectal tumours. This data provides a unique insight into the biochemical…

Machine Learning · Computer Science 2016-11-17 Christopher Roadknight , Durga Suryanarayanan , Uwe Aickelin , John Scholefield , Lindy Durrant

Non-small cell lung cancer (NSCLC) is a serious disease and has a high recurrence rate after the surgery. Recently, many machine learning methods have been proposed for recurrence prediction. The methods using gene data have high prediction…

Computer Vision and Pattern Recognition · Computer Science 2021-04-30 Panyanat Aonpong , Yutaro Iwamoto , Xian-Hua Han , Lanfen Lin , Yen-Wei Chen

Understanding how deep learning models predict oncology patient risk can provide critical insights into disease progression, support clinical decision-making, and pave the way for trustworthy and data-driven precision medicine. Building on…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Marvin Sextro , Gabriel Dernbach , Kai Standvoss , Simon Schallenberg , Frederick Klauschen , Klaus-Robert Müller , Maximilian Alber , Lukas Ruff

In this proposed work, we identified the significant research issues on lung cancer risk factors. Capturing and defining symptoms at an early stage is one of the most difficult phases for patients. Based on the history of patients records,…

Image and Video Processing · Electrical Eng. & Systems 2023-04-12 Muhammad Sohaib , Mary Adewunmi

Cancer remains a leading global health challenge and a major cause of mortality. This study leverages machine learning (ML) to predict the survivability of cancer patients with metastatic patterns using the comprehensive MSK-MET dataset,…

Quantitative Methods · Quantitative Biology 2025-04-10 Polycarp Nalela , Deepthi Rao , Praveen Rao

Lung cancer is the leading cause of cancer related mortality by a significant margin. While new technologies, such as image segmentation, have been paramount to improved detection and earlier diagnoses, there are still significant…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Marguerite B. Basta , Sarfaraz Hussein , Hsiang Hsu , Flavio P. Calmon