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High quality gene models are necessary to expand the molecular and genetic tools available for a target organism, but these are available for only a handful of model organisms that have undergone extensive curation and experimental…

Traditional image annotation tasks rely heavily on human effort for object selection and label assignment, making the process time-consuming and prone to decreased efficiency as annotators experience fatigue after extensive work. This paper…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 He Zhang , Xinyi Fu , John M. Carroll

Manual annotation of medical images is a labor-intensive and time-consuming process, posing a significant bottleneck in the development and deployment of robust medical imaging AI systems. This paper introduces a novel hands-free Human-AI…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yizhe Zhang

In this position paper, we discuss the potential for leveraging LLMs as interactive research tools to facilitate collaboration between human coders and AI to effectively annotate online risk data at scale. Collaborative human-AI labeling is…

Human-Computer Interaction · Computer Science 2024-04-12 Jinkyung Park , Pamela Wisniewski , Vivek Singh

Developing safe, effective, and practically useful clinical prediction models (CPMs) traditionally requires iterative collaboration between clinical experts, data scientists, and informaticists. This process refines the often small but…

Artificial Intelligence · Computer Science 2026-01-15 Jean Feng , Avni Kothari , Patrick Vossler , Andrew Bishara , Lucas Zier , Newton Addo , Aaron Kornblith , Yan Shuo Tan , Chandan Singh

Academic writing is an indispensable yet laborious part of the research enterprise. This Perspective maps out principles and methods for using generative artificial intelligence (AI), specifically large language models (LLMs), to elevate…

Computers and Society · Computer Science 2026-04-07 Zhicheng Lin

Single-cell RNA sequencing has transformed our ability to identify diverse cell types and their transcriptomic signatures. However, annotating these signatures-especially those involving poorly characterized genes-remains a major challenge.…

Effective data-driven biomedical discovery requires data curation: a time-consuming process of finding, organizing, distilling, integrating, interpreting, annotating, and validating diverse information into a structured form suitable for…

Collaborative human-AI annotation is a promising approach for various tasks with large-scale and complex data. Tools and methods to support effective human-AI collaboration for data annotation are an important direction for research. In…

Human-Computer Interaction · Computer Science 2024-09-24 Jinkyung Katie Park , Rahul Dev Ellezhuthil , Pamela Wisniewski , Vivek Singh

Nowadays, due to the increasing amount of experimental data obtained by sequencing, the most interest is focused on determining the functions and characteristics of its individual parts of the genome instead of determining the nucleotide…

Genomics · Quantitative Biology 2021-02-09 Marina Galchenkova , Aleksei Korzhenkov

Scientific disciplines, such as Behavioural Psychology, Anthropology and recently Social Signal Processing are concerned with the systematic exploration of human behaviour. A typical work-flow includes the manual annotation (also called…

Human-Computer Interaction · Computer Science 2018-02-21 Johannes Wagner , Tobias Baur , Yue Zhang , Michel F. Valstar , Björn Schuller , Elisabeth André

Automated text annotation is a compelling use case for generative large language models (LLMs) in social media research. Recent work suggests that LLMs can achieve strong performance on annotation tasks; however, these studies evaluate LLMs…

Computation and Language · Computer Science 2024-09-24 Nicholas Pangakis , Samuel Wolken

Despite growing interest in using large language models (LLMs) to automate annotation, their effectiveness in complex, nuanced, and multi-dimensional labelling tasks remains relatively underexplored. This study focuses on annotation for the…

Information Retrieval · Computer Science 2025-07-02 Leila Tavakoli , Hamed Zamani

The generation of high-quality assemblies, even for large eukaryotic genomes, has become a routine task for many biologists thanks to recent advances in sequencing technologies. However, the annotation of these assemblies - a crucial step…

Genomics · Quantitative Biology 2021-04-07 Roman Martin , Thomas Hackl , Georges Hattab , Matthias G. Fischer , Dominik Heider

Segmentation and genome annotation (SAGA) algorithms are widely used to understand genome activity and gene regulation. These algorithms take as input epigenomic datasets, such as chromatin immunoprecipitation-sequencing (ChIP-seq)…

Genomics · Quantitative Biology 2022-06-14 Maxwell W Libbrecht , Rachel CW Chan , Michael M Hoffman

While there is a widespread belief that artificial general intelligence (AGI) -- or even superhuman AI -- is imminent, complex problems in expert domains are far from being solved. We argue that such problems require human-AI cooperation…

Human-AI collaborative tools attract attentions from the data storytelling community to lower the expertise barrier and streamline the workflow. The recent advance in large-scale generative AI techniques, e.g., large language models (LLMs)…

Human-Computer Interaction · Computer Science 2025-10-31 Haotian Li , Yun Wang , Huamin Qu

Generative AI has the potential to transform knowledge work, but further research is needed to understand how knowledge workers envision using and interacting with generative AI. We investigate the development of generative AI tools to…

The use of artificial intelligence (AI) in working environments with individuals, known as Human-AI Collaboration (HAIC), has become essential in a variety of domains, boosting decision-making, efficiency, and innovation. Despite HAIC's…

Human-Computer Interaction · Computer Science 2025-03-10 George Fragiadakis , Christos Diou , George Kousiouris , Mara Nikolaidou

We introduce a novel framework for human-AI collaboration in prediction and decision tasks. Our approach leverages human judgment to distinguish inputs which are algorithmically indistinguishable, or "look the same" to any feasible…

Machine Learning · Computer Science 2024-10-21 Rohan Alur , Loren Laine , Darrick K. Li , Dennis Shung , Manish Raghavan , Devavrat Shah
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