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Accurate segmentation of organs and tumors in CT and MRI scans is essential for diagnosis, treatment planning, and disease monitoring. While deep learning has advanced automated segmentation, most models remain task-specific, lacking…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Yuheng Li , Yizhou Wu , Yuxiang Lai , Mingzhe Hu , Xiaofeng Yang

Domain generalization (DG) strives to address distribution shifts across diverse environments to enhance model's generalizability. Current DG approaches are confined to acquiring robust representations with continuous features, specifically…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Shaocong Long , Qianyu Zhou , Xikun Jiang , Chenhao Ying , Lizhuang Ma , Yuan Luo

Deep learning (DL)-based models have demonstrated good performance in medical image segmentation. However, the models trained on a known dataset often fail when performed on an unseen dataset collected from different centers, vendors and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Lei Li , Veronika A. Zimmer , Wangbin Ding , Fuping Wu , Liqin Huang , Julia A. Schnabel , Xiahai Zhuang

Foundation models (FMs) have shown transformative potential in radiology by performing diverse, complex tasks across imaging modalities. Here, we developed CT-FM, a large-scale 3D image-based pre-trained model designed explicitly for…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Suraj Pai , Ibrahim Hadzic , Dennis Bontempi , Keno Bressem , Benjamin H. Kann , Andriy Fedorov , Raymond H. Mak , Hugo J. W. L. Aerts

Domain shift presents a significant challenge in applying Deep Learning to the segmentation of 3D medical images from sources like Magnetic Resonance Imaging (MRI) and Computed Tomography (CT). Although numerous Domain Adaptation methods…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Boris Shirokikh , Anvar Kurmukov , Mariia Donskova , Valentin Samokhin , Mikhail Belyaev , Ivan Oseledets

Machine learning systems generally assume that the training and testing distributions are the same. To this end, a key requirement is to develop models that can generalize to unseen distributions. Domain generalization (DG), i.e.,…

Machine Learning · Computer Science 2022-05-25 Jindong Wang , Cuiling Lan , Chang Liu , Yidong Ouyang , Tao Qin , Wang Lu , Yiqiang Chen , Wenjun Zeng , Philip S. Yu

Machine learning and computer vision methods are showing good performance in medical imagery analysis. Yetonly a few applications are now in clinical use and one of the reasons for that is poor transferability of themodels to data from…

Image and Video Processing · Electrical Eng. & Systems 2020-10-15 Ekaterina Kondrateva , Marina Pominova , Elena Popova , Maxim Sharaev , Alexander Bernstein , Evgeny Burnaev

Most prior unsupervised domain adaptation approaches for medical image segmentation are narrowly tailored to either the source-accessible setting, where adaptation is guided by source-target alignment, or the source-free setting, which…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Xin Wang , Yin Guo , Jiamin Xia , Kaiyu Zhang , Niranjan Balu , Mahmud Mossa-Basha , Linda Shapiro , Chun Yuan

Deep learning models have exhibited exceptional effectiveness in Computational Pathology (CPath) by tackling intricate tasks across an array of histology image analysis applications. Nevertheless, the presence of out-of-distribution data…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 Mostafa Jahanifar , Manahil Raza , Kesi Xu , Trinh Vuong , Rob Jewsbury , Adam Shephard , Neda Zamanitajeddin , Jin Tae Kwak , Shan E Ahmed Raza , Fayyaz Minhas , Nasir Rajpoot

Medical image segmentation plays an important role in many image-guided clinical approaches. However, existing segmentation algorithms mostly rely on the availability of fully annotated images with pixel-wise annotations for training, which…

Computer Vision and Pattern Recognition · Computer Science 2024-04-23 Yuyan Shi , Jialu Ma , Jin Yang , Shasha Wang , Yichi Zhang

Traditional domain generalization methods often rely on domain alignment to reduce inter-domain distribution differences and learn domain-invariant representations. However, domain shifts are inherently difficult to eliminate, which limits…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Yuheng Xu , Taiping Zhang

The need to address the scarcity of task-specific annotated data has resulted in concerted efforts in recent years for specific settings such as zero-shot learning (ZSL) and domain generalization (DG), to separately address the issues of…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Shivam Chandhok , Sanath Narayan , Hisham Cholakkal , Rao Muhammad Anwer , Vineeth N Balasubramanian , Fahad Shahbaz Khan , Ling Shao

Medical image segmentation is vital for clinical diagnosis, yet current deep learning methods often demand extensive expert effort, i.e., either through annotating large training datasets or providing prompts at inference time for each new…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Xingjian Li , Qifeng Wu , Adithya S. Ubaradka , Yiran Ding , Colleen Que , Runmin Jiang , Jianhua Xing , Tianyang Wang , Min Xu

Medical image artificial intelligence models often achieve strong performance in single-center or single-device settings, yet their effectiveness frequently deteriorates in real-world cross-center deployment due to domain shift, limiting…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Jingsong Xia , Siqi Wang

The Segment Anything Model (SAM) and similar models build a family of promptable foundation models (FMs) for image and video segmentation. The object of interest is identified using prompts, such as bounding boxes or points. With these FMs…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Caroline Magg , Hoel Kervadec , Clara I. Sánchez

Convolutional neural networks have been widely applied to medical image segmentation and have achieved considerable performance. However, the performance may be significantly affected by the domain gap between training data (source domain)…

Image and Video Processing · Electrical Eng. & Systems 2022-07-28 Junyan Lyu , Yiqi Zhang , Yijin Huang , Li Lin , Pujin Cheng , Xiaoying Tang

Domain Generalization (DG) is a challenging task in machine learning that requires a coherent ability to comprehend shifts across various domains through extraction of domain-invariant features. DG performance is typically evaluated by…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Yiran Luo , Joshua Feinglass , Tejas Gokhale , Kuan-Cheng Lee , Chitta Baral , Yezhou Yang

Single-source domain generalization (SDG) in medical image segmentation is a challenging yet essential task as domain shifts are quite common among clinical image datasets. Previous attempts most conduct global-only/random augmentation.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Zixian Su , Kai Yao , Xi Yang , Qiufeng Wang , Jie Sun , Kaizhu Huang

Recently, large-scale pre-trained models such as Segment-Anything Model (SAM) and Contrastive Language-Image Pre-training (CLIP) have demonstrated remarkable success and revolutionized the field of computer vision. These foundation vision…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Shichao Dong , Fayao Liu , Guosheng Lin

Graph foundation models (GFMs) have recently attracted interest due to the promise of graph neural network (GNN) architectures that generalize zero-shot across graphs of arbitrary scales, feature dimensions, and domains. While existing work…

Machine Learning · Computer Science 2026-03-25 Benjamin Gutteridge , Michael Bronstein , Xiaowen Dong