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Domain generalization for Diabetic Retinopathy (DR) classification allows a model to adeptly classify retinal images from previously unseen domains with various imaging conditions and patient demographics, thereby enhancing its…

Computer Vision and Pattern Recognition · Computer Science 2023-09-21 Sharon Chokuwa , Muhammad H. Khan

Medical Foundation Models (MFMs), trained on large-scale datasets, have demonstrated superior performance across various tasks. However, these models still struggle with domain gaps in practical applications. Specifically, even after…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Jia-Xuan Jiang , Wenhui Lei , Yifeng Wu , Hongtao Wu , Furong Li , Yining Xie , Xiaofan Zhang , Zhong Wang

Medical image segmentation poses challenges due to domain gaps, data modality variations, and dependency on domain knowledge or experts, especially for low- and middle-income countries (LMICs). Whereas for humans, given a few exemplars…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Chen Xu , Qiming Huang , Yuqi Hou , Jiangxing Wu , Fan Zhang , Hyung Jin Chang , Jianbo Jiao

Machine learning models are prone to overfitting their training (source) domains, which is commonly believed to be the reason why they falter in novel target domains. Here we examine the contrasting view that multi-source domain…

Computation and Language · Computer Science 2022-10-26 Md Arafat Sultan , Avirup Sil , Radu Florian

The success of large language models has inspired the computer vision community to explore image segmentation foundation model that is able to zero/few-shot generalize through prompt engineering. Segment-Anything(SAM), among others, is the…

Computer Vision and Pattern Recognition · Computer Science 2024-04-11 Haojie Zhang , Yongyi Su , Xun Xu , Kui Jia

Accurate medical image segmentation is essential for effective diagnosis and treatment planning but is often challenged by domain shifts caused by variations in imaging devices, acquisition conditions, and patient-specific attributes.…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Jie Bao , Zhixin Zhou , Wen Jung Li , Rui Luo

Despite the remarkable success of deep learning in medical imaging analysis, medical image segmentation remains challenging due to the scarcity of high-quality labeled images for supervision. Further, the significant domain gap between…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Hedda Cohen Indelman , Elay Dahan , Angeles M. Perez-Agosto , Carmit Shiran , Doron Shaked , Nati Daniel

Developing predictive models that perform reliably across diverse patient populations and heterogeneous environments is a core aim of medical research. However, generalization is only possible if the learned model is robust to statistical…

As the leading cause of death worldwide, cardiovascular diseases motivate the development of more sophisticated methods to analyze the heart and its substructures from medical images like Computed Tomography (CT) and Magnetic Resonance…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Franz Thaler , Darko Stern , Gernot Plank , Martin Urschler

Domain generalization (DG) has been a hot topic in image recognition, with a goal to train a general model that can perform well on unseen domains. Recently, federated learning (FL), an emerging machine learning paradigm to train a global…

Computer Vision and Pattern Recognition · Computer Science 2022-10-04 Junming Chen , Meirui Jiang , Qi Dou , Qifeng Chen

Deep learning models for medical image analysis easily suffer from distribution shifts caused by dataset artifacts bias, camera variations, differences in the imaging station, etc., leading to unreliable diagnoses in real-world clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Siyuan Yan , Chi Liu , Zhen Yu , Lie Ju , Dwarikanath Mahapatra , Brigid Betz-Stablein , Victoria Mar , Monika Janda , Peter Soyer , Zongyuan Ge

Over the past decades, computer-aided diagnosis tools for breast cancer have been developed to enhance screening procedures, yet their clinical adoption remains challenged by data variability and inherent biases. Although foundation models…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Elodie Germani , Ilayda Selin Türk , Fatima Zeineddine , Charbel Mourad , Shadi Albarqouni

Deep learning models trained with large amounts of data have become a recent and effective approach to predictive problem solving -- these have become known as "foundation models" as they can be used as fundamental tools for other…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 José Guilherme de Almeida , Nuno M. Rodrigues , Sara Silva , Nickolas Papanikolaou

Domain generalization (DG) is a difficult transfer learning problem aiming to learn a generalizable model for unseen domains. Recent foundation models (FMs) are robust to many distribution shifts and, therefore, should substantially improve…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Xin Zhang , Shixiang Shane Gu , Yutaka Matsuo , Yusuke Iwasawa

The domain generalization problem has been widely investigated in deep learning for non-contrast imaging over the last years, but it received limited attention for contrast-enhanced imaging. However, there are marked differences in contrast…

Medical images often exhibit distribution shifts due to variations in imaging protocols and scanners across different medical centers. Domain Generalization (DG) methods aim to train models on source domains that can generalize to unseen…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Yihang Fu , Ziyang Chen , Yiwen Ye , Xingliang Lei , Zhisong Wang , Yong Xia

In medical image segmentation across multiple modalities (e.g., MRI, CT, etc.) and heterogeneous data sources (e.g., different hospitals and devices), Domain Generalization (DG) remains a critical challenge in AI-driven healthcare. This…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Yucheng Song , Chenxi Li , Haokang Ding , Zhining Liao , Zhifang Liao

Recently, the diffusion model has emerged as a superior generative model that can produce high quality and realistic images. However, for medical image translation, the existing diffusion models are deficient in accurately retaining…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 Yunxiang Li , Hua-Chieh Shao , Xiao Liang , Liyuan Chen , Ruiqi Li , Steve Jiang , Jing Wang , You Zhang

Medical foundation models have shown promise in controlled benchmarks, yet widespread deployment remains hindered by reliance on task-specific fine-tuning. Here, we introduce DermFM-Zero, a dermatology vision-language foundation model…

The topic of generalizing machine learning models learned on a collection of source domains to unknown target domains is challenging. While many domain generalization (DG) methods have achieved promising results, they primarily rely on the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-20 Xingchen Zhao , Chang Liu , Anthony Sicilia , Seong Jae Hwang , Yun Fu
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