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Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

Digital health analytics face critical challenges nowadays. The sophisticated analysis of patient-generated health content, which contains complex emotional and medical contexts, requires scarce domain expertise, while traditional ML…

Clinical notes are often stored in unstructured or semi-structured formats after extraction from electronic medical record (EMR) systems, which complicates their use for secondary analysis and downstream clinical applications. Reliable…

Computation and Language · Computer Science 2025-12-30 Risha Surana , Adrian Law , Sunwoo Kim , Rishab Sridhar , Angxiao Han , Peiyu Hong

Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

Computation and Language · Computer Science 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

Structured Electronic Health Record (EHR) data stores patient information in relational tables and plays a central role in clinical decision-making. Recent advances have explored the use of large language models (LLMs) to process such data,…

Artificial Intelligence · Computer Science 2026-04-02 Xiao Yang , Xuejiao Zhao , Zhiqi Shen

Health systems are rapidly deploying large language models (LLMs) that use clinical notes for clinical decision support applications. However, modern documentation practices rely heavily on templates, copy--paste shortcuts, and…

Computers and Society · Computer Science 2026-04-21 Jordan L. Cahoon , Chloe Stanwyck , Asad Aali , Rachel Madding , Emma Sun , Yixing Jiang , Renumathy Dhanasekaran , Emily Alsentzer

Large language models (LLMs) have shown promise in safety-critical applications such as healthcare, yet the ability to quantify performance has lagged. An example of this challenge is in evaluating a summary of the patient's medical record.…

Computation and Language · Computer Science 2024-11-13 Elliot Schumacher , Daniel Rosenthal , Dhruv Naik , Varun Nair , Luladay Price , Geoffrey Tso , Anitha Kannan

Chronic diseases such as diabetes are the leading causes of morbidity and mortality worldwide. Numerous research studies have been attempted with various deep learning models in diagnosis. However, most previous studies had certain…

Writing discharge summaries to transfer medical information is an important but time-consuming process that can be assisted by Large Language Models (LLMs). This prospective mixed methods pilot study evaluated an Electronic Health Record…

We explore how large language models (LLMs) can enhance the proposal selection process at large user facilities, offering a scalable, consistent, and cost-effective alternative to traditional human review. Proposal selection depends on…

Artificial Intelligence · Computer Science 2025-12-12 Lijie Ding , Janell Thomson , Jon Taylor , Changwoo Do

The growing demand for home healthcare calls for tools that can support care delivery. In this study, we explore automatic health assessment from voice using real-world home care visit data, leveraging the diverse patient information it…

Audio and Speech Processing · Electrical Eng. & Systems 2025-10-22 Yu-Wen Chen , William Ho , Sasha M. Vergez , Grace Flaherty , Pallavi Gupta , Zhihong Zhang , Maryam Zolnoori , Margaret V. McDonald , Maxim Topaz , Zoran Kostic , Julia Hirschberg

As two important textual modalities in electronic health records (EHR), both structured data (clinical codes) and unstructured data (clinical narratives) have recently been increasingly applied to the healthcare domain. Most existing…

Computation and Language · Computer Science 2022-11-01 Sicen Liu , Xiaolong Wang , Yongshuai Hou , Ge Li , Hui Wang , Hui Xu , Yang Xiang , Buzhou Tang

Clinical notes recorded during a patient's perioperative journey holds immense informational value. Advances in large language models (LLMs) offer opportunities for bridging this gap. Using 84,875 pre-operative notes and its associated…

Computation and Language · Computer Science 2025-04-03 Charles Alba , Bing Xue , Joanna Abraham , Thomas Kannampallil , Chenyang Lu

Identifying disease phenotypes from electronic health records (EHRs) is critical for numerous secondary uses. Manually encoding physician knowledge into rules is particularly challenging for rare diseases due to inadequate EHR coding,…

Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare…

Machine Learning · Computer Science 2018-10-24 Edward Choi , Cao Xiao , Walter F. Stewart , Jimeng Sun

Conventional machine learning models, particularly tree-based approaches, have demonstrated promising performance across various clinical prediction tasks using electronic health record (EHR) data. Despite their strengths, these models…

Computation and Language · Computer Science 2025-05-26 Sara Ketabi , Dhanesh Ramachandram

Large language models (LLMs) show promise in automating clinical diagnosis, yet their non-transparent decision-making and limited alignment with diagnostic standards hinder trust and clinical adoption. We address this challenge by proposing…

Artificial Intelligence · Computer Science 2025-11-25 Yining Yuan , J. Ben Tamo , Micky C. Nnamdi , Yifei Wang , May D. Wang

Large language models (LLMs) are becoming increasingly relevant as a potential tool for healthcare, aiding communication between clinicians, researchers, and patients. However, traditional evaluations of LLMs on medical exam questions do…

Computation and Language · Computer Science 2023-09-19 Rojin Ziaei , Samuel Schmidgall

Medical documentation, including discharge notes, is crucial for ensuring patient care quality, continuity, and effective medical communication. However, the manual creation of these documents is not only time-consuming but also prone to…

Computation and Language · Computer Science 2024-04-09 HyoJe Jung , Yunha Kim , Heejung Choi , Hyeram Seo , Minkyoung Kim , JiYe Han , Gaeun Kee , Seohyun Park , Soyoung Ko , Byeolhee Kim , Suyeon Kim , Tae Joon Jun , Young-Hak Kim

Large language models (LLMs) show promise for clinical reasoning and decision support, but evaluation in realistic, electronic health record-congruent settings remains limited. Existing benchmarks often rely on static datasets or…

Computation and Language · Computer Science 2026-05-29 Valentina Bui Muti , Eugénie Dulout , Ziquan Fu