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Taking advantage of the widespread use of ontologies to organise and harmonize knowledge across several distinct domains, this paper proposes a novel approach to improve an embedding-Large Language Model (embedding-LLM) of interest by…

Computation and Language · Computer Science 2024-06-03 Francesco Ronzano , Jay Nanavati

Addressing the challenge of limited annotated data in specialized fields and low-resource languages is crucial for the effective use of Language Models (LMs). While most Large Language Models (LLMs) are trained on general-purpose English…

Computation and Language · Computer Science 2024-07-31 Serena Auriemma , Martina Miliani , Mauro Madeddu , Alessandro Bondielli , Lucia Passaro , Alessandro Lenci

Ontologies are useful for automatic machine processing of domain knowledge as they represent it in a structured format. Yet, constructing ontologies requires substantial manual effort. To automate part of this process, large language models…

Machine Learning · Computer Science 2024-11-01 Andy Lo , Albert Q. Jiang , Wenda Li , Mateja Jamnik

Large Language Models (LLMs) are increasingly being integrated into various components of Ontology Matching pipelines. This paper investigates the capability of LLMs to perform ontology matching directly on ontology modules and generate the…

Computation and Language · Computer Science 2025-12-01 Guilherme Sousa , Rinaldo Lima , Cassia Trojahn

Masked language modelling (MLM) as a pretraining objective has been widely adopted in genomic sequence modelling. While pretrained models can successfully serve as encoders for various downstream tasks, the distribution shift between…

Machine Learning · Computer Science 2025-02-26 Monireh Safari , Pablo Millan Arias , Scott C. Lowe , Lila Kari , Angel X. Chang , Graham W. Taylor

In the realm of predictive analytics, the nuanced domain knowledge of investigators often remains underutilized, confined largely to subjective interpretations and ad hoc decision-making. This paper explores the potential of Large Language…

Machine Learning · Computer Science 2024-05-15 Phoebe Jing , Yijing Gao , Yuanhang Zhang , Xianlong Zeng

Domain-specific knowledge can significantly contribute to addressing a wide variety of vision tasks. However, the generation of such knowledge entails considerable human labor and time costs. This study investigates the potential of Large…

Background. Endowing intelligent systems with semantic data commonly requires designing and instantiating ontologies with domain-specific knowledge. Especially in the early phases, those activities are typically performed manually by human…

Artificial Intelligence · Computer Science 2025-01-24 Giovanni Ciatto , Andrea Agiollo , Matteo Magnini , Andrea Omicini

Recently, there has been a growing interest in Multimodal Large Language Models (MLLMs) due to their remarkable potential in various tasks integrating different modalities, such as image and text, as well as applications such as image…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Jihen Amara , Birgitta König-Ries , Sheeba Samuel

Existing domain-specific Large Language Models (LLMs) are typically developed by fine-tuning general-purposed LLMs with large-scale domain-specific corpora. However, training on large-scale corpora often fails to effectively organize domain…

Computation and Language · Computer Science 2025-02-11 Zhiqiang Liu , Chengtao Gan , Junjie Wang , Yichi Zhang , Zhongpu Bo , Mengshu Sun , Huajun Chen , Wen Zhang

Large Language Models (LLMs) have shown significant potential for ontology engineering. However, it is still unclear to what extent they are applicable to the task of domain-specific ontology generation. In this study, we explore the…

Multimodal large language models (MLLMs) have shown remarkable capabilities in multimodal perception and understanding tasks. However, their effectiveness in specialized domains, such as remote sensing and medical imaging, remains limited.…

Computation and Language · Computer Science 2026-02-05 Qinglong Cao , Yuntian Chen , Chao Ma , Xiaokang Yang

We investigate the task of inserting new concepts extracted from texts into an ontology using language models. We explore an approach with three steps: edge search which is to find a set of candidate locations to insert (i.e., subsumptions…

Computation and Language · Computer Science 2024-03-05 Hang Dong , Jiaoyan Chen , Yuan He , Yongsheng Gao , Ian Horrocks

This work presents an ontology-integrated large language model (LLM) framework for chemical engineering that unites structured domain knowledge with generative reasoning. The proposed pipeline aligns model training and inference with the…

Machine Learning · Computer Science 2025-12-15 Crystal Su , Kuai Yu , Jingrui Zhang , Mingyuan Shao , Daniel Bauer

Pre-trained Large Language Models (LLMs) often struggle on out-of-domain datasets like healthcare focused text. We explore specialized pre-training to adapt smaller LLMs to different healthcare datasets. Three methods are assessed:…

Computation and Language · Computer Science 2024-04-01 Niall Taylor , Dan Schofield , Andrey Kormilitzin , Dan W Joyce , Alejo Nevado-Holgado

Pretraining DNA language models (DNALMs) on the full human genome is resource-intensive, yet often considered necessary for strong downstream performance. Inspired by recent findings in NLP and long-context modeling, we explore an…

Genomics · Quantitative Biology 2025-06-24 Sohan Mupparapu , Parameswari Krishnamurthy , Ratish Puduppully

Large Language Models (LLMs) have demonstrated remarkable success in various tasks such as natural language understanding, text summarization, and machine translation. However, their general-purpose nature often limits their effectiveness…

Computation and Language · Computer Science 2025-09-03 Zirui Song , Bin Yan , Yuhan Liu , Miao Fang , Mingzhe Li , Rui Yan , Xiuying Chen

Large Language Models (LLMs) have demonstrated remarkable proficiency in understanding and generating natural language. However, their capabilities wane in highly specialized domains underrepresented in the pretraining corpus, such as…

Machine Learning · Computer Science 2024-07-29 Junhong Shen , Neil Tenenholtz , James Brian Hall , David Alvarez-Melis , Nicolo Fusi

This thesis provides methods and analysis of models which make progress on this goal. The techniques outlined are task agnostic, and should provide benefit when used with nearly any transformer LM. We introduce two new finetuning methods…

Computation and Language · Computer Science 2024-08-30 Davis Yoshida

Clinical natural language processing requires methods that can address domain-specific challenges, such as complex medical terminology and clinical contexts. Recently, large language models (LLMs) have shown promise in this domain. Yet,…

Computation and Language · Computer Science 2025-01-28 Ran Xu , Hejie Cui , Yue Yu , Xuan Kan , Wenqi Shi , Yuchen Zhuang , Wei Jin , Joyce Ho , Carl Yang
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