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Designing a single neural network architecture that performs competitively across a range of molecule property prediction tasks remains largely an open challenge, and its solution may unlock a widespread use of deep learning in the drug…

Machine Learning · Computer Science 2021-02-10 Łukasz Maziarka , Tomasz Danel , Sławomir Mucha , Krzysztof Rataj , Jacek Tabor , Stanisław Jastrzębski

Vectorized quantum block encoding provides a way to embed classical data into Hilbert space, offering a pathway for quantum models, such as Quantum Transformers (QT), that replace classical self-attention with quantum circuit simulations to…

Quantum Physics · Physics 2025-09-05 Ziqing Guo , Ziwen Pan , Alex Khan , Jan Balewski

In this work, quantum transformers are designed and analysed in detail by extending the state-of-the-art classical transformer neural network architectures known to be very performant in natural language processing and image analysis.…

Accurate prediction of cancer type and primary tumor site is critical for effective diagnosis, personalized treatment, and improved outcomes. Traditional models struggle with the complexity of genomic and clinical data, but quantum…

Quantitative Methods · Quantitative Biology 2025-06-30 Don Roosan , Rubayat Khan , Md Rahatul Ashakin , Tiffany Khou , Saif Nirzhor , Mohammad Rifat Haider

The success of the self-attention mechanism in classical machine learning models has inspired the development of quantum analogs aimed at reducing computational overhead. Self-attention integrates learnable query and key matrices to…

Recent advances in quantum computing have opened new pathways for enhancing deep learning architectures, particularly in domains characterized by high-dimensional and context-rich data such as natural language processing (NLP). In this…

Computation and Language · Computer Science 2025-06-30 S. M. Yousuf Iqbal Tomal , Abdullah Al Shafin , Debojit Bhattacharjee , MD. Khairul Amin , Rafiad Sadat Shahir

We present a novel hybrid quantum-classical vision transformer architecture incorporating quantum orthogonal neural networks (QONNs) to enhance performance and computational efficiency in high-energy physics applications. Building on…

Quantum computers have the potential to simulate chemical systems beyond the capability of classical computers. Recent developments in hybrid quantum-classical approaches enable the determinations of the ground or low energy states of…

Quantum Physics · Physics 2021-12-06 Chee-Kong Lee , Jonathan Wei Zhong Lau , Liang Shi , Leong Chuan Kwek

Quantum machine learning is a promising direction for building more efficient and expressive models, particularly in domains where understanding complex, structured data is critical. We present the Quantum Graph Transformer (QGT), a hybrid…

Computation and Language · Computer Science 2025-06-10 Shamminuj Aktar , Andreas Bärtschi , Abdel-Hameed A. Badawy , Stephan Eidenbenz

Quantum phase transitions in many-body systems are fundamentally characterized by complex correlation structures, which pose computational challenges for conventional methods in large systems. To address this, we propose a hybrid…

Quantum Physics · Physics 2026-02-03 Jin-Long Chen , Xin Li , Zhang-Qi Yin

Variational quantum circuits (VQCs) are a leading approach to quantum machine learning on near-term devices, yet it remains unclear which circuit architecture yields the best accuracy-parameter trade-off on classical tabular data. We…

Quantum Physics · Physics 2026-04-28 Chi-Sheng Chen , En-Jui Kuo

Inspired by the advancements in large language models based on transformers, we introduce the transformer quantum state (TQS): a versatile machine learning model for quantum many-body problems. In sharp contrast to Hamiltonian/task specific…

Quantum Physics · Physics 2023-03-08 Yuan-Hang Zhang , Massimiliano Di Ventra

Machine learning on quantum computers has attracted attention for its potential to deliver computational speedups in different tasks. However, deep variational quantum circuits require a large number of trainable parameters that grows with…

Machine Learning (ML) has been widely applied across numerous domains due to its ability to automatically identify informative patterns from data for various tasks. The availability of large-scale data and advanced computational power…

In this paper, we address the challenge of multivariate time-series forecasting using quantum machine learning techniques. We introduce adaptation strategies that extend variational quantum circuit models, traditionally limited to…

Molecular dynamic simulations are important in computational physics, chemistry, material, and biology. Machine learning-based methods have shown strong abilities in predicting molecular energy and properties and are much faster than DFT…

Molecular Networks · Quantitative Biology 2023-02-03 Zheng Yuan , Yaoyun Zhang , Chuanqi Tan , Wei Wang , Fei Huang , Songfang Huang

We introduces the Quantum-Train(QT) framework, a novel approach that integrates quantum computing with classical machine learning algorithms to address significant challenges in data encoding, model compression, and inference hardware…

Understanding the properties of excited states of complex molecules is crucial for many chemical and physical processes. Calculating these properties is often significantly more resource-intensive than calculating their ground state…

Quantum Physics · Physics 2025-05-08 Manuel Hagelüken , Marco F. Huber , Marco Roth

We developed a general theoretical approach and a user-ready computer code that permit to study the dynamics of collisional energy transfer and ro-vibrational energy exchange in complex molecule-molecule collisions. The method is a mixture…

Chemical Physics · Physics 2024-02-06 Carolin Joy , Bikramaditya Mandal , Dulat Bostan , Marie-Lise Dubernet , Dmitri Babikov

Quantum Transformers integrate the representational power of classical Transformers with the computational advantages of quantum computing. Since 2022, research in this area has rapidly expanded, giving rise to diverse technical paradigms…

Quantum Physics · Physics 2025-12-01 Hui Zhang , Qinglin Zhao , Mengchu Zhou , Li Feng , Dusit Niyato , Shenggen Zheng , Lin Chen
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