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At the intersection of machine learning and quantum computing, Quantum Machine Learning (QML) has the potential of accelerating data analysis, especially for quantum data, with applications for quantum materials, biochemistry, and…

Quantum Physics · Physics 2023-03-17 M. Cerezo , Guillaume Verdon , Hsin-Yuan Huang , Lukasz Cincio , Patrick J. Coles

Quantum computing and machine learning have potential for symbiosis. However, in addition to the hardware limitations from current devices, there are still basic issues that must be addressed before quantum circuits can usefully incorporate…

Quantum Physics · Physics 2022-06-15 Fabio Sanches , Sean Weinberg , Takanori Ide , Kazumitsu Kamiya

We introduce the Momentum Transformer, an attention-based deep-learning architecture, which outperforms benchmark time-series momentum and mean-reversion trading strategies. Unlike state-of-the-art Long Short-Term Memory (LSTM)…

Machine Learning · Computer Science 2022-11-24 Kieran Wood , Sven Giegerich , Stephen Roberts , Stefan Zohren

Accurate and efficient prediction of electronic wavefunctions is central to ab initio molecular dynamics (AIMD) and electronic structure theory. However, conventional ab initio methods require self-consistent optimization of electronic…

Chemical Physics · Physics 2025-11-12 Yanxian Tao , Lingyun Wan , Xiongzhi Zeng , Yingdi Jin , Jie Liu , Zhenyu Li , Jinlong Yang

Quantum Machine Learning has the potential to improve traditional machine learning methods and overcome some of the main limitations imposed by the classical computing paradigm. However, the practical advantages of using quantum resources…

Quantum Physics · Physics 2023-03-21 Antonio Macaluso , Matthias Klusch , Stefano Lodi , Claudio Sartori

Quantum machine learning (QML) leverages quantum computing for classical inference, furnishes the processing of quantum data with machine-learning methods, and provides quantum algorithms adapted to noisy devices. Typically, QML proposals…

Quantum Physics · Physics 2026-05-11 Luis Mantilla Calderón , Robert Raussendorf , Polina Feldmann , Dmytro Bondarenko

Quantum algorithms for simulating large and complex molecular systems are still in their infancy, and surpassing state-of-the-art classical techniques remains an ever-receding goal post. A promising avenue of inquiry in the meanwhile is to…

Quantum Physics · Physics 2025-08-07 Soohaeng Yoo Willow , D. ChangMo Yang , Chang Woo Myung

Binding energy is a fundamental thermodynamic property that governs molecular interactions, playing a crucial role in fields such as healthcare and the natural sciences. It is particularly relevant in drug development, vaccine design, and…

Quantum Physics · Physics 2025-08-06 Erico Souza Teixeira , Lucas Barros Fernandes , Yara Rodrigues Inácio

The ability to perform ab initio molecular dynamics simulations using potential energies calculated on quantum computers would allow virtually exact dynamics for chemical and biochemical systems, with substantial impacts on the fields of…

Quantum convolutional neural networks (QCNNs) have gathered attention as one of the most promising algorithms for quantum machine learning. Reduction in the cost of training as well as improvement in performance is required for practical…

Quantum computational chemistry holds great promise for simulating molecular systems more efficiently than classical methods by leveraging quantum bits to represent molecular wavefunctions. However, current implementations face significant…

Quantum Physics · Physics 2025-09-10 Weitang Li , Shi-Xin Zhang , Zirui Sheng , Cunxi Gong , Jianpeng Chen , Zhigang Shuai

Offline reinforcement learning enables policy learning from pre-collected datasets without environment interaction, but existing Decision Transformer (DT) architectures struggle with long-horizon credit assignment and complex state-action…

Machine Learning · Computer Science 2025-12-18 Abraham Itzhak Weinberg

Neural network quantum state (NNQS) has emerged as a promising candidate for quantum many-body problems, but its practical applications are often hindered by the high cost of sampling and local energy calculation. We develop a…

Quantum Physics · Physics 2023-11-02 Yangjun Wu , Chu Guo , Yi Fan , Pengyu Zhou , Honghui Shang

Unlike vision and language data which usually has a unique format, molecules can naturally be characterized using different chemical formulations. One can view a molecule as a 2D graph or define it as a collection of atoms located in a 3D…

Machine Learning · Computer Science 2023-03-29 Shengjie Luo , Tianlang Chen , Yixian Xu , Shuxin Zheng , Tie-Yan Liu , Liwei Wang , Di He

High-throughput approximations of quantum mechanics calculations and combinatorial experiments have been traditionally used to reduce the search space of possible molecules, drugs and materials. However, the interplay of structural and…

Quantum Physics · Physics 2019-10-29 Alain Tchagang , Julio Valdés

Modeling long-range dependencies in sequential data remains a central challenge in machine learning. Transformers address this challenge through attention mechanisms, but their quadratic complexity with respect to sequence length limits…

Machine Learning · Computer Science 2026-05-14 Hoang-Quan Nguyen , Sankalp Pandey , Khoa Luu

In recent years, molecular representation learning has emerged as a key area of focus in various chemical tasks. However, many existing models fail to fully consider the geometric information of molecular structures, resulting in less…

Machine Learning · Computer Science 2023-06-29 Bumju Kwak , Jiwon Park , Taewon Kang , Jeonghee Jo , Byunghan Lee , Sungroh Yoon

Hybrid quantum and classical learning aims to couple quantum feature maps with the robustness of classical neural networks, yet most architectures treat the quantum circuit as an isolated feature extractor and merge its measurements with…

Machine Learning · Computer Science 2025-12-23 Azadeh Alavi , Fatemeh Kouchmeshki , Abdolrahman Alavi

Quantum machine learning algorithms are expected to play a pivotal role in quantum chemistry simulations in the immediate future. One such key application is the training of a quantum neural network to learn the potential energy surface and…

Quantum Physics · Physics 2024-09-04 Gabriele Lo Monaco , Marco Bertini , Salvatore Lorenzo , G. Massimo Palma

Quantum computation represents a promising frontier in the domain of high-performance computing, blending quantum information theory with practical applications to overcome the limitations of classical computation. This study investigates…

Quantum Physics · Physics 2025-01-23 King Yiu Yu , Aritra Sarkar , Maximilian Rimbach-Russ , Ryoichi Ishihara , Sebastian Feld