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Computational protein design facilitates discovery of novel proteins with prescribed structure and functionality. Exciting designs were recently reported using novel data-driven methodologies that can be roughly divided into two categories:…

Biological Physics · Physics 2023-03-28 Cyril Malbranke , David Bikard , Simona Cocco , Rémi Monasson , Jérôme Tubiana

The paradigm shift from environment-unaware communication to intelligent environment-aware communication is expected to facilitate the acquisition of channel state information for future wireless communications. Channel Fingerprint (CF), as…

Networking and Internet Architecture · Computer Science 2026-05-27 Zhenzhou Jin , Li You , Xiang-Gen Xia , Xiqi Gao

While deep generative models show promise for learning inverse protein folding directly from data, the lack of publicly available structure-sequence pairings limits their generalization. Previous improvements and data augmentation efforts…

Artificial Intelligence · Computer Science 2024-07-23 Jiangbin Zheng , Stan Z. Li

Mammography is the most commonly used imaging modality for breast cancer screening, driving an increasing demand for deep-learning techniques to support large-scale analysis. However, the development of accurate and robust methods is often…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Xin Li , Kaixiang Yang , Qiang Li , Zhiwei Wang

Data-driven deep learning models have enabled tremendous progress in change detection (CD) with the support of pixel-level annotations. However, collecting diverse data and manually annotating them is costly, laborious, and…

Computer Vision and Pattern Recognition · Computer Science 2024-12-23 Qi Zang , Jiayi Yang , Shuang Wang , Dong Zhao , Wenjun Yi , Zhun Zhong

We tackle the common challenge of inter-concept visual confusion in compositional concept generation using text-guided diffusion models (TGDMs). It becomes even more pronounced in the generation of customized concepts, due to the scarcity…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Wang Lin , Jingyuan Chen , Jiaxin Shi , Yichen Zhu , Chen Liang , Junzhong Miao , Tao Jin , Zhou Zhao , Fei Wu , Shuicheng Yan , Hanwang Zhang

Stable diffusion models represent the state-of-the-art in data synthesis across diverse domains and hold transformative potential for applications in science and engineering, e.g., by facilitating the discovery of novel solutions and…

Machine Learning · Computer Science 2025-10-23 Stefano Zampini , Jacob K. Christopher , Luca Oneto , Davide Anguita , Ferdinando Fioretto

Protein structure prediction and folding are fundamental to understanding biology, with recent deep learning advances reshaping the field. Diffusion-based generative models have revolutionized protein design, enabling the creation of novel…

Machine Learning · Computer Science 2025-10-01 Yogesh Verma , Markus Heinonen , Vikas Garg

Recent advances in generative modeling -- particularly diffusion models and flow matching -- have achieved remarkable success in synthesizing discrete data such as images and videos. However, adapting these models to physical applications…

Machine Learning · Computer Science 2025-11-26 Sifan Wang , Zehao Dou , Siming Shan , Tong-Rui Liu , Lu Lu

The dyadic reaction generation task involves synthesizing responsive facial reactions that align closely with the behaviors of a conversational partner, enhancing the naturalness and effectiveness of human-like interaction simulations. This…

Machine Learning · Computer Science 2025-05-14 Minh-Duc Nguyen , Hyung-Jeong Yang , Soo-Hyung Kim , Ji-Eun Shin , Seung-Won Kim

The emergence of text-driven motion synthesis technique provides animators with great potential to create efficiently. However, in most cases, textual expressions only contain general and qualitative motion descriptions, while lack fine…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Dong Wei , Xiaoning Sun , Huaijiang Sun , Bin Li , Shengxiang Hu , Weiqing Li , Jianfeng Lu

A robust face recognition model must be trained using datasets that include a large number of subjects and numerous samples per subject under varying conditions (such as pose, expression, age, noise, and occlusion). Due to ethical and…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Bernardo Biesseck , Pedro Vidal , Luiz Coelho , Roger Granada , David Menotti|

Diffusion models, a powerful and universal generative AI technology, have achieved tremendous success in computer vision, audio, reinforcement learning, and computational biology. In these applications, diffusion models provide flexible…

Machine Learning · Computer Science 2024-04-12 Minshuo Chen , Song Mei , Jianqing Fan , Mengdi Wang

The ability to automatically generate music that appropriately matches an arbitrary input track is a challenging task. We present a novel controllable system for generating single stems to accompany musical mixes of arbitrary length. At the…

Sound · Computer Science 2024-02-05 Marco Pasini , Maarten Grachten , Stefan Lattner

Recent advances in vision-language pre-training have enabled machines to perform better in multimodal object discrimination (e.g., image-text semantic alignment) and image synthesis (e.g., text-to-image generation). On the other hand,…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Xiao Dong , Runhui Huang , Xiaoyong Wei , Zequn Jie , Jianxing Yu , Jian Yin , Xiaodan Liang

Protein structure prediction is pivotal for understanding the structure-function relationship of proteins, advancing biological research, and facilitating pharmaceutical development and experimental design. While deep learning methods and…

Machine Learning · Computer Science 2024-12-30 Kaihui Cheng , Ce Liu , Qingkun Su , Jun Wang , Liwei Zhang , Yining Tang , Yao Yao , Siyu Zhu , Yuan Qi

Artificial Intelligence (AI) based image analysis has an immense potential to support diagnostic histopathology, including cancer diagnostics. However, developing supervised AI methods requires large-scale annotated datasets. A potentially…

Feature selection is fundamental to robust data-centric AI, but most existing methods optimize predictive performance under a single data distribution. This often selects spurious features that fail under distribution shifts. Motivated by…

Machine Learning · Computer Science 2026-03-24 Arun Vignesh Malarkkan , Xinyuan Wang , Kunpeng Liu , Denghui Zhang , Yanjie Fu

Recent advancements in diffusion models have showcased their impressive capacity to generate visually striking images. Nevertheless, ensuring a close match between the generated image and the given prompt remains a persistent challenge. In…

Computer Vision and Pattern Recognition · Computer Science 2023-09-11 Yupeng Zhou , Daquan Zhou , Zuo-Liang Zhu , Yaxing Wang , Qibin Hou , Jiashi Feng

Structure-based drug design (SBDD), aiming to generate 3D molecules with high binding affinity toward target proteins, is a vital approach in novel drug discovery. Although recent generative models have shown great potential, they suffer…

Machine Learning · Computer Science 2025-11-05 Jingyuan Zhou , Hao Qian , Shikui Tu , Lei Xu