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State-of-the-art computer- and robot-assisted surgery systems heavily depend on intraoperative imaging technologies such as CT and fluoroscopy to generate detailed 3D visualization of the patient's anatomy. While imaging techniques are…

Image and Video Processing · Electrical Eng. & Systems 2024-10-04 Aidana Massalimova , Florentin Liebmann , Sascha Jecklin , Fabio Carrillo , Farshad Mazda , Philipp Fürnstahl

Ultrasound Tomography has seen a revival of interest in the past decade, especially for breast imaging, due to improvements in both ultrasound and computing hardware. In particular, three-dimensional ultrasound tomography, a fully…

Computational Physics · Physics 2020-05-27 Ashkan Javaherian , Felix Lucka , Ben Cox

We present a proof of concept for screening breast cancer risk by detecting biochemical alterations in breast tissue using a noninvasive and low-cost technique that uses dynamic light scattering for field effect detection by spectral…

Medical Physics · Physics 2026-04-07 Janeth Fernández-Pinto , Álvaro Gómez-Torrado , David A. Miranda

Determining the 3D pose of a patient from a limited set of 2D X-ray images is a critical task in interventional settings. While preoperative volumetric imaging (e.g., CT and MRI) provides precise 3D localization and visualization of…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Vivek Gopalakrishnan , Neel Dey , Polina Golland

Unsafe surgical care is a critical health concern, often linked to limitations in surgeon experience, skills, and situational awareness. Integrating patient-specific 3D models into the surgical field can enhance visualization, provide…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Alberto Neri , Veronica Penza , Nazim Haouchine , Leonardo S. Mattos

We propose an anatomically-informed initialisation method for interpatient CT non-rigid registration (NRR), using a learning-based model to estimate correspondences between organ structures. A thin plate spline (TPS) deformation, set up…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Edward G. A. Henderson , Marcel van Herk , Andrew F. Green , Eliana M. Vasquez Osorio

Goal: A limitation in robotic surgery is the lack of force feedback, due to challenges in suitable sensing techniques. To enhance the perception of the surgeons and precise force rendering, estimation of these forces along with tissue…

Systems and Control · Electrical Eng. & Systems 2025-04-30 Srikar Annamraju , Yuxi Chen , Jooyoung Lim , Inki Kim

Purpose: To analyze a recently published chest radiography foundation model for the presence of biases that could lead to subgroup performance disparities across biological sex and race. Materials and Methods: This retrospective study used…

Machine Learning · Computer Science 2023-10-03 Ben Glocker , Charles Jones , Melanie Roschewitz , Stefan Winzeck

Purpose: We aimed to develop a data-driven multiomics approach integrating radiomics, dosiomics, and delta features to predict treatment response at an earlier stage (intra-treatment) for brain metastases (BMs) patients treated with PULSAR.…

Evidence is accumulating in favour of using stereotactic ablative body radiotherapy (SABR) to treat multiple cancer lesions in the lung. Multi-lesion lung SABR plans are complex and require significant resources to create. In this work, we…

Medical Physics · Physics 2024-07-12 Edward Wang , Ryan Au , Pencilla Lang , Sarah A. Mattonen

Gross tumor volume (GTV) delineation on tomography medical imaging is crucial for radiotherapy planning and cancer diagnosis. Convolutional neural networks (CNNs) has been predominated on automatic 3D medical segmentation tasks, including…

Image and Video Processing · Electrical Eng. & Systems 2020-12-15 Chun-Hung Chao , Hsien-Tzu Cheng , Tsung-Ying Ho , Le Lu , Min Sun

PURPOSE: Magnetic Resonance Fingerprinting (MRF) with spiral readout enables rapid quantification of tissue relaxation times. However, it is prone to blurring due to off-resonance effects. Hence, fat blurring into adjacent regions might…

We investigated the effects of scanning speed, beam configuration, and dose-rate modeling on the FLASH effect in post-mastectomy proton transmission-beam (TB) planning and evaluated whether optimizing the spot-scanning path can enhance…

A standard treatment protocol for breast cancer entails administering neoadjuvant therapy followed by surgical removal of the tumor and surrounding tissue. Pathologists typically rely on cabinet X-ray radiographs, known as Faxitron, to…

Image and Video Processing · Electrical Eng. & Systems 2024-01-19 Negar Golestani , Aihui Wang , Gregory R Bean , Mirabela Rusu

The aim of this study is to use image-processing techniques developed in the field of astrophysics as inspiration for a novel approach to the three-dimensional (3D) imaging of periprocedural medical data, with the intention of providing…

Medical Physics · Physics 2019-02-05 I. Brewis , J. A. McLaughlin

Radiation therapy outcomes are decided by two key parameters, dose and timing, whose best values vary substantially across patients. This variability is especially critical in the treatment of brain cancer, where fractionated or staged…

Medical Physics · Physics 2025-06-24 Hao Peng , Steve Jiang , Robert Timmerman

Breast cancer is one of the main causes of death worldwide. Histopathological cellularity assessment of residual tumors in post-surgical tissues is used to analyze a tumor's response to a therapy. Correct cellularity assessment increases…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Alexander Rakhlin , Aleksei Tiulpin , Alexey A. Shvets , Alexandr A. Kalinin , Vladimir I. Iglovikov , Sergey Nikolenko

In current clinical practice, noisy and artifact-ridden weekly cone-beam computed tomography (CBCT) images are only used for patient setup during radiotherapy. Treatment planning is done once at the beginning of the treatment using…

Image and Video Processing · Electrical Eng. & Systems 2022-01-02 Navdeep Dahiya , Sadegh R Alam , Pengpeng Zhang , Si-Yuan Zhang , Anthony Yezzi , Saad Nadeem

Radiotherapy aims to deliver a prescribed dose to the tumor while sparing neighboring organs at risk (OARs). Increasingly complex treatment techniques such as volumetric modulated arc therapy (VMAT), stereotactic radiosurgery (SRS),…

Medical Physics · Physics 2023-10-23 Elahheh Salari , Jing Wang , Jacob Wynne , Chih-Wei Chang , Xiaofeng Yang

Breast X-ray CT imaging is being considered in screening as an extension to mammography. As a large fraction of the population will be exposed to radiation, low-dose imaging is essential. Iterative image reconstruction based on solving an…

Medical Physics · Physics 2011-11-14 Jakob H. Jørgensen , Emil Y. Sidky , Xiaochuan Pan