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Advancements in the capabilities of Large Language Models (LLMs) have created a promising foundation for developing autonomous agents. With the right tools, these agents could learn to solve tasks in new environments by accumulating and…
Memory-augmented LLM agents maintain external memory banks to support long-horizon interaction, yet most existing systems treat construction, retrieval, and utilization as isolated subroutines. This creates two coupled challenges: strategic…
As the population of older adults increases, there is a growing need for support for them to age in place. This is exacerbated by the growing number of individuals struggling with cognitive decline and shrinking number of youth who provide…
Inspired by the dual-process theory of human cognition, we introduce DUMA, a novel conversational agent framework that embodies a dual-mind mechanism through the utilization of two generative Large Language Models (LLMs) dedicated to fast…
Dementia is a progressive neurodegenerative disorder with multiple etiologies, including Alzheimer's disease, Parkinson's disease, frontotemporal dementia, and vascular dementia. Its clinical and biological heterogeneity makes diagnosis and…
A number of life threatening neuro-degenerative disorders had degraded the quality of life for the older generation in particular. Dementia is one such symptom which may lead to a severe condition called Alzheimer's disease if not detected…
Mental disorders represent a critical global health challenge, and social media is increasingly viewed as a vital resource for real-time digital phenotyping and intervention. To leverage this data, large language models (LLMs) have been…
Procedural memory enables large language model (LLM) agents to internalize "how-to" knowledge, theoretically reducing redundant trial-and-error. However, existing frameworks predominantly suffer from a "passive accumulation" paradigm,…
Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that leads to dementia, and early intervention can greatly benefit from analyzing linguistic abnormalities. In this work, we explore the potential of Large Language Models…
Effective mental health counseling is a complex, theory-driven process requiring the simultaneous integration of psychological frameworks, real-time distress signals, and strategic intervention planning. This level of clinical reasoning is…
Agent memory shapes how Large Language Model (LLM)-powered agents, akin to the human brain, progressively refine themselves through environment interactions. Existing paradigms remain constrained: parametric memory forcibly adjusts model…
As the number of dementia patients rises, the need for accurate diagnostic procedures rises as well. Current methods, like using an MRI scan, rely on human input, which can be inaccurate. However, the decision logic behind machine learning…
Complex dialog systems often use retrieved evidence to facilitate factual responses. Such RAG (Retrieval Augmented Generation) systems retrieve from massive heterogeneous data stores that are usually architected as multiple indexes or APIs…
Recent advancements have highlighted that Large Language Models (LLMs) are prone to hallucinations when solving complex reasoning problems, leading to erroneous results. To tackle this issue, researchers incorporate Knowledge Graphs (KGs)…
Individuals with Alzheimer's disease (AD) and Alzheimer's disease-related dementia (ADRD) experience memory and thinking changes that impact their ability to use digital daily management tools. For example, adding an event to a digital…
Graph Neural Networks (GNNs) have achieved remarkable success in graph-based learning by propagating information among neighbor nodes via predefined aggregation mechanisms. However, such fixed schemes often suffer from two key limitations.…
Patients with semantic dementia (SD) present with remarkably consistent atrophy of neurons in the anterior temporal lobe and behavioural impairments, such as graded loss of category knowledge. While relearning of lost knowledge has been…
Large Language Models (LLMs) based agents have demonstrated remarkable potential in autonomous task-solving across complex, open-ended environments. A promising approach for improving the reasoning capabilities of LLM agents is to better…
Large language models (LLMs) have demonstrated remarkable capabilities in a wide range of tasks, yet their application to specialized domains remains challenging due to the need for deep expertise. Retrieval-Augmented generation (RAG) has…
Generative agents powered by language models are increasingly deployed for long-horizon tasks. However, as long-term memory context grows over time, they struggle to maintain coherence. This deficiency leads to critical failures, including…