Related papers: DEMENTIA-PLAN: An Agent-Based Framework for Multi-…

Large Language Models (LLMs) have been increasingly adopted for health-related tasks, yet their performance in depression detection remains limited when relying solely on text input. While Retrieval-Augmented Generation (RAG) typically…

Dementia is a neurological syndrome marked by cognitive decline. Alzheimer's disease (AD) and Frontotemporal dementia (FTD) are the common forms of dementia, each with distinct progression patterns. EEG, a non-invasive tool for recording…

Mental health counseling remains a major challenge in modern society due to cost, stigma, fear, and unavailability. We posit that generative artificial intelligence (AI) models designed for mental health counseling could help improve…

Retrieval-Augmented Generation (RAG) systems enable large language models (LLMs) instant access to relevant information for the generative process, demonstrating their superior performance in addressing common LLM challenges such as…

In this study, we propose a novel human-like memory architecture designed for enhancing the cognitive abilities of large language model based dialogue agents. Our proposed architecture enables agents to autonomously recall memories…

Older adults commonly experience chronic conditions such as pain and sleep disturbances and may consider cannabidiol for symptom management. Safe use requires appropriate dosing, careful titration, and awareness of drug interactions, yet…

Large language models (LLMs) increasingly serve as the central control unit of AI agents, yet current approaches remain limited in their ability to deliver personalized interactions. While Retrieval Augmented Generation enhances LLM…

We introduce a novel large language model (LLM)-driven agent framework, which iteratively refines queries and filters contextual evidence by leveraging dynamically evolving knowledge. A defining feature of the system is its decoupling of…

Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease. Early and precise diagnosis of AD is crucial for timely intervention and treatment planning to alleviate the progressive neurodegeneration. However, most…

Psychological counseling is a fundamentally multimodal cognitive process in which clinicians integrate verbal content with visual and vocal cues to infer clients' mental states and respond empathically. However, most existing…

Large language models deployed as autonomous agents face critical memory limitations, lacking selective forgetting mechanisms that lead to either catastrophic forgetting at context boundaries or information overload within them. While human…

\textbf{Objective:} Alzheimer's disease (AD) is the most prevalent form of dementia worldwide, encompassing a prodromal stage known as Mild Cognitive Impairment (MCI), where patients may either progress to AD or remain stable. The objective…

Machine learning methods exploiting multi-parametric biomarkers, especially based on neuroimaging, have huge potential to improve early diagnosis of dementia and to predict which individuals are at-risk of developing dementia. To benchmark…

In this paper we describe the requirements and early system design for a smart conversational agent that can assist older adults in the reminiscence process. The practice of reminiscence has well documented benefits for the mental, social…

Recent advances in large language models (LLMs) have scaled the potential for reasoning and agentic search, wherein models autonomously plan, retrieve, and reason over external knowledge to answer complex queries. However, the iterative…

Early diagnosis of Alzheimer's disease and related dementias (ADRD) is critical for timely intervention, yet most diagnoses are delayed until advanced stages. While comprehensive patient narratives are essential for accurate diagnosis,…

We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural…

As artificial neural networks grow in complexity, understanding their inner workings becomes increasingly challenging, which is particularly important in healthcare applications. The intrinsic evaluation metrics of autoregressive neural…

Alzheimer's disease (AD) is a common form of dementia that severely impacts patient health. As AD impairs the patient's language understanding and expression ability, the speech of AD patients can serve as an indicator of this disease. This…

With populations ageing, the number of people with dementia worldwide is expected to triple to 152 million by 2050. Seventy percent of cases are due to Alzheimer's disease (AD) pathology and there is a 10-20 year 'pre-clinical' period…