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While deep learning has achieved great success in many fields, one common criticism about deep learning is its lack of interpretability. In most cases, the hidden units in a deep neural network do not have a clear semantic meaning or…

Genomics · Quantitative Biology 2019-06-04 Tianle Ma , Aidong Zhang

Using evolutionary computation algorithms to solve multiple tasks with knowledge sharing is a promising approach. Image feature learning can be considered as a multitask problem because different tasks may have a similar feature space.…

Computer Vision and Pattern Recognition · Computer Science 2021-07-16 Ying Bi , Bing Xue , Mengjie Zhang

Knowledge Graphs have been one of the fundamental methods for integrating heterogeneous data sources. Integrating heterogeneous data sources is crucial, especially in the biomedical domain, where central data-driven tasks such as drug…

Machine Learning · Computer Science 2020-12-22 Islam Akef Ebeid , Majdi Hassan , Tingyi Wanyan , Jack Roper , Abhik Seal , Ying Ding

Unraveling the co-expression of genes across studies enhances the understanding of cellular processes. Inferring gene co-expression networks from transcriptome data presents many challenges, including spurious gene correlations, sample…

Machine Learning · Statistics 2024-10-01 Teodora Pandeva , Martijs Jonker , Leendert Hamoen , Joris Mooij , Patrick Forré

Drug discovery and development is a complex and costly process. Machine learning approaches are being investigated to help improve the effectiveness and speed of multiple stages of the drug discovery pipeline. Of these, those that use…

Artificial Intelligence · Computer Science 2022-09-27 Stephen Bonner , Ian P Barrett , Cheng Ye , Rowan Swiers , Ola Engkvist , Andreas Bender , Charles Tapley Hoyt , William L Hamilton

As an efficient model for knowledge organization, the knowledge graph has been widely adopted in several fields, e.g., biomedicine, sociology, and education. And there is a steady trend of learning embedding representations of knowledge…

Computation and Language · Computer Science 2024-04-01 Siyu Yao , Ruijie Wang , Shen Sun , Derui Bu , Jun Liu

The identification of disease-gene associations is instrumental in understanding the mechanisms of diseases and developing novel treatments. Besides identifying genes from RNA-Seq datasets, it is often necessary to identify gene clusters…

Genomics · Quantitative Biology 2025-11-14 Jake R. Patock , Rinki Ratnapriya , Arko Barman

Graph neural networks (GNNs) have achieved extraordinary enhancements in various areas including the fields medical imaging and network neuroscience where they displayed a high accuracy in diagnosing challenging neurological disorders such…

Machine Learning · Computer Science 2022-09-14 Mehmet Yigit Balik , Arwa Rekik , Islem Rekik

Despite the remarkable success achieved by graph convolutional networks for functional brain activity analysis, the heterogeneity of functional patterns and the scarcity of imaging data still pose challenges in many tasks. Transferring…

Machine Learning · Computer Science 2022-12-19 Wenhui Cui , Haleh Akrami , Anand A. Joshi , Richard M. Leahy

Knowledge transfer among multiple networks using their outputs or intermediate activations have evolved through extensive manual design from a simple teacher-student approach (knowledge distillation) to a bidirectional cohort one (deep…

Computer Vision and Pattern Recognition · Computer Science 2019-12-18 Soma Minami , Tsubasa Hirakawa , Takayoshi Yamashita , Hironobu Fujiyoshi

Combining different modalities of data from human tissues has been critical in advancing biomedical research and personalised medical care. In this study, we leverage a graph embedding model (i.e VGAE) to perform link prediction on…

Genomics · Quantitative Biology 2021-07-27 Amine Amor , Pietro Lio' , Vikash Singh , Ramon Viñas Torné , Helena Andres Terre

Aiming at the limitations of traditional medical decision system in processing large-scale heterogeneous medical data and realizing highly personalized recommendation, this paper introduces a personalized medical decision algorithm…

Machine Learning · Computer Science 2024-05-29 Yafeng Yan , Shuyao He , Zhou Yu , Jiajie Yuan , Ziang Liu , Yan Chen

A key obstacle in automated analytics and meta-learning is the inability to recognize when different datasets contain measurements of the same variable. Because provided attribute labels are often uninformative in practice, this task may be…

Machine Learning · Computer Science 2019-09-12 Jonas Mueller , Alex Smola

Deep learning has been widely adopted in automatic emotion recognition and has lead to significant progress in the field. However, due to insufficient annotated emotion datasets, pre-trained models are limited in their generalization…

Computer Vision and Pattern Recognition · Computer Science 2020-06-25 Dung Nguyen , Sridha Sridharan , Duc Thanh Nguyen , Simon Denman , David Dean , Clinton Fookes

Knowledge Graph embedding provides a versatile technique for representing knowledge. These techniques can be used in a variety of applications such as completion of knowledge graph to predict missing information, recommender systems,…

Information Retrieval · Computer Science 2021-07-19 Shivani Choudhary , Tarun Luthra , Ashima Mittal , Rajat Singh

We propose a unified cross-domain transfer learning framework that leverages knowledge from multiple heterogeneous medical imaging datasets to improve performance across segmentation, classification, and object detection tasks. Our approach…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Ceausescu Ciprian-Mihai , Anghelina Ion-Marian , Alexe Dumitru-Bogdan

Learning effective embedding has been proved to be useful in many real-world problems, such as recommender systems, search ranking and online advertisement. However, one of the challenges is data sparsity in learning large-scale item…

Machine Learning · Computer Science 2019-05-27 Yi Ouyang , Bin Guo , Xing Tang , Xiuqiang He , Jian Xiong , Zhiwen Yu

Nowadays, it is common in Historical Demography the use of individual-level data as a consequence of a predominant life-course approach for the understanding of the demographic behaviour, family transition, mobility, etc. Record linkage…

Artificial Intelligence · Computer Science 2020-03-09 B. Gautam , O. Ramos Terrades , J. M. Pujades , M. Valls

Transfer learning has emerged as a powerful technique in many application problems, such as computer vision and natural language processing. However, this technique is largely ignored in application to genetic data analysis. In this paper,…

Applications · Statistics 2022-06-22 Jinghang Lin , Shan Zhang , Qing Lu

Graph neural networks (GNNs) are powerful machine learning models designed to handle irregularly structured data. However, their generic design often proves inadequate for analyzing brain connectomes in Alzheimer's Disease (AD),…

Machine Learning · Computer Science 2024-12-10 Zhepeng Wang , Runxue Bao , Yawen Wu , Guodong Liu , Lei Yang , Liang Zhan , Feng Zheng , Weiwen Jiang , Yanfu Zhang