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Hypergraphs provide an effective modeling approach for modeling high-order relationships in many real-world datasets. To capture such complex relationships, several hypergraph neural networks have been proposed for learning hypergraph…

Machine Learning · Computer Science 2024-04-08 Rongping Ye , Xiaobing Pei , Haoran Yang , Ruiqi Wang

Molecular interactions often involve high-order relationships that cannot be fully captured by traditional graph-based models limited to pairwise connections. Hypergraphs naturally extend graphs by enabling multi-way interactions, making…

Machine Learning · Computer Science 2025-05-12 Tien Dang , Truong-Son Hy

Contagion processes in social systems often involve interactions that go beyond pairwise contacts. Higher-order networks, represented as hypergraphs, have been widely used to model multi-body interactions, and their presence can drastically…

Physics and Society · Physics 2026-01-26 Andrés Guzmán , Federico Malizia , István Z. Kiss

Temporal Graph Neural Networks (TGNNs) have gained growing attention for modeling and predicting structures in temporal graphs. However, existing TGNNs primarily focus on pairwise interactions while overlooking higher-order structures that…

Machine Learning · Computer Science 2025-05-22 Jingzhe Liu , Zhigang Hua , Yan Xie , Bingheng Li , Harry Shomer , Yu Song , Kaveh Hassani , Jiliang Tang

Traditional functional connectivity based on functional magnetic resonance imaging (fMRI) can only capture pairwise interactions between brain regions. Hypergraphs, which reveal high-order relationships among multiple brain regions, have…

Neurons and Cognition · Quantitative Biology 2025-05-20 Wenqi Hu , Xuerui Su , Guanliang Li , Yidi Pan , Aijing Lin

Among various spatio-temporal prediction tasks, epidemic forecasting plays a critical role in public health management. Recent studies have demonstrated the strong potential of spatio-temporal graph neural networks (STGNNs) in extracting…

Machine Learning · Computer Science 2025-12-30 Yufan Zheng , Wei Jiang , Tong Chen , Alexander Zhou , Nguyen Quoc Viet Hung , Choujun Zhan , Hongzhi Yin

Since the onset of the COVID-19 pandemic, there has been a growing interest in studying epidemiological models. Traditional mechanistic models mathematically describe the transmission mechanisms of infectious diseases. However, they often…

Machine Learning · Computer Science 2024-09-10 Zewen Liu , Guancheng Wan , B. Aditya Prakash , Max S. Y. Lau , Wei Jin

Epidemic forecasting is the key to effective control of epidemic transmission and helps the world mitigate the crisis that threatens public health. To better understand the transmission and evolution of epidemics, we propose EpiGNN, a graph…

Quantitative Methods · Quantitative Biology 2022-08-25 Feng Xie , Zhong Zhang , Liang Li , Bin Zhou , Yusong Tan

Biomedical interaction networks have incredible potential to be useful in the prediction of biologically meaningful interactions, identification of network biomarkers of disease, and the discovery of putative drug targets. Recently, graph…

Machine Learning · Computer Science 2021-03-29 Kishan KC , Rui Li , Feng Cui , Anne Haake

Hypergraphs offer a generalized framework for capturing high-order relationships between entities and have been widely applied in various domains, including healthcare, social networks, and bioinformatics. Hypergraph neural networks, which…

Machine Learning · Computer Science 2025-12-03 Akash Choudhuri , Yongjian Zhong , Bijaya Adhikari

Graph representation learning for hypergraphs can be used to extract patterns among higher-order interactions that are critically important in many real world problems. Current approaches designed for hypergraphs, however, are unable to…

Machine Learning · Computer Science 2019-11-11 Ruochi Zhang , Yuesong Zou , Jian Ma

Modelling epidemic events such as COVID-19 cases in both time and space dimensions is an important but challenging task. Building on in-depth review and assessment of two popular graph neural network (GNN)-based regional epidemic…

Computation · Statistics 2025-11-20 Xiangxin Kong , Hang Wang , Yutong Li , Yanghao Chen , Zudi Lu

Epidemic prediction is a fundamental task for epidemic control and prevention. Many mechanistic models and deep learning models are built for this task. However, most mechanistic models have difficulty estimating the time/region-varying…

Computers and Society · Computer Science 2023-06-28 Qi Cao , Renhe Jiang , Chuang Yang , Zipei Fan , Xuan Song , Ryosuke Shibasaki

Hypergraphs, describing networks where interactions take place among any number of units, are a natural tool to model many real-world social and biological systems. In this work we propose a principled framework to model the organization of…

Social and Information Networks · Computer Science 2023-10-25 Nicolò Ruggeri , Martina Contisciani , Federico Battiston , Caterina De Bacco

Accurate epidemic forecasting is crucial for effective disease control and prevention. Traditional compartmental models often struggle to estimate temporally and spatially varying epidemiological parameters, while deep learning models…

Machine Learning · Computer Science 2025-04-08 Shuai Han , Lukas Stelz , Thomas R. Sokolowski , Kai Zhou , Horst Stöcker

Human mobility forms the backbone of contact patterns through which infectious diseases propagate, fundamentally shaping the spatio-temporal dynamics of epidemics and pandemics. While traditional models are often based on the assumption…

Graph representation learning (GRL) has emerged as an effective technique for modeling graph-structured data. When modeling heterogeneity and dynamics in real-world complex networks, GRL methods designed for complex heterogeneous temporal…

Social and Information Networks · Computer Science 2026-05-19 Huan Liu , Pengfei Jiao , Mengzhou Gao , Chaochao Chen , Di Jin

Hypergraph neural networks (HGNNs) effectively model complex high-order relationships in domains like protein interactions and social networks by connecting multiple vertices through hyperedges, enhancing modeling capabilities, and reducing…

Machine Learning · Computer Science 2025-12-08 Yue Gao , Yifan Feng , Shiquan Liu , Xiangmin Han , Shaoyi Du , Zongze Wu , Han Hu

Knowledge hypergraphs generalize knowledge graphs using hyperedges to connect multiple entities and depict complicated relations. Existing methods either transform hyperedges into an easier-to-handle set of binary relations or view…

Machine Learning · Computer Science 2024-12-18 Mengfan Li , Xuanhua Shi , Chenqi Qiao , Teng Zhang , Hai Jin

In this paper, we present a hypergraph neural networks (HGNN) framework for data representation learning, which can encode high-order data correlation in a hypergraph structure. Confronting the challenges of learning representation for…

Machine Learning · Computer Science 2019-02-26 Yifan Feng , Haoxuan You , Zizhao Zhang , Rongrong Ji , Yue Gao
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