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Purpose: Anthropomorphic phantoms can be used in radiotherapy to confirm dose distributions. In this work, a prototype phantom with a deformable chest wall was created based on real human. Methods: A technique similar to 3-dimensional…

Medical Physics · Physics 2021-11-11 Maria Akiki , Fadi Rouphael , Mazen Moussallem

Purpose: To develop a radiomics filtering technique for characterizing spatial-encoded regional pulmonary ventilation information on lung CT. Methods: The lung volume was segmented on 46 CT images, and a 3D sliding window kernel was…

Medical Physics · Physics 2023-01-11 Zhenyu Yang , Kyle J Lafata , Xinru Chen , James Bowsher , Yushi Chang , Chunhao Wang , Fang-Fang Yin

Volume calculation from the Computed Tomography (CT) lung lesions data is a significant parameter for clinical diagnosis. The volume is widely used to assess the severity of the lung nodules and track its progression, however, the accuracy…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Liansheng Wang , Shusheng Li , Shuo Li

Computational anatomy allows the quantitative analysis of organs in medical images. However, most analysis is constrained to the millimeter scale because of the limited resolution of clinical computed tomography (CT). X-ray microtomography…

Computer Vision and Pattern Recognition · Computer Science 2017-02-28 Holger R. Roth , Kai Nagara , Hirohisa Oda , Masahiro Oda , Tomoshi Sugiyama , Shota Nakamura , Kensaku Mori

The goal of this work was to build an anthropomorphic thorax phantom capable of breathing motion with materials mimicking human tissues in x-ray imaging applications. The thorax phantom, named Casper, was composed of resin (body), foam…

The inherent characteristics of lung tissues, which are independent of breathing manoeuvre, may provide fundamental information on lung function. This paper attempted to study function-correlated lung textures and their spatial distribution…

Medical Physics · Physics 2024-03-28 Yu-Hua Huang , Xinzhi Teng , Jiang Zhang , Zhi Chen , Zongrui Ma , Ge Ren , Feng-Ming , Kong , Jing Cai

Clinical imaging trials play a crucial role in advancing medical innovation but are often costly, inefficient, and ethically constrained. Virtual Imaging Trials (VITs) present a solution by simulating clinical trial components in a…

Different clinical elastography devices show different liver-stiffness values in the same subject, hindering comparison of values and establishment of system-independent thresholds for disease detection. Therefore, authorities request…

Ultrasound computed tomography (USCT) is an emerging imaging modality for breast imaging that can produce quantitative images that depict the acoustic properties of tissues. Computer-simulation studies, also known as virtual imaging trials,…

Medical Physics · Physics 2022-06-24 Fu Li , Umberto Villa , Seonyeong Park , Mark A. Anastasio

While drastic improvements in CT technology have occurred in the past 25 years, spatial resolution is one area where progress has been limited until recently. New photon counting CT systems, are capable of much better spatial resolution…

Background: Accurate chamber volumetry from gated, non-contrast cardiac CT (NCCT) scans can be useful for potential screening of heart failure. Objectives: To validate a new, fully automated, AI-based method for cardiac volume and…

Background: X-ray grating-based dark-field imaging can sense the small angle scattering caused by an object's micro-structure. This technique is sensitive to lung's porous alveoli and is able to detect lung disease at an early stage. Up to…

Medical Physics · Physics 2024-05-03 Peiyuan Guo , Simon Spindler , Li Zhang , Zhentian Wang

We present a robust technique for calculating regional volume changes within the lung from X-ray radiograph sequences captured during ventilation, without the use of computed tomography (CT). This technique is based on the change in…

Cystic fibrosis is a genetic disease which may appear in early life with structural abnormalities in lung tissues. We propose to detect these abnormalities using a texture classification approach. Our method is a cascade of two…

Computer Vision and Pattern Recognition · Computer Science 2018-03-22 Filipe Marques , Florian Dubost , Mariette Kemner-van de Corput , Harm A. W. Tiddens , Marleen de Bruijne

Consistency and duplicability in Computed Tomography (CT) output is essential to quantitative imaging for lung cancer detection and monitoring. This study of CT-detected lung nodules investigated the reproducibility of volume-, density-,…

Medical imaging phantoms are widely used for validation and verification of imaging systems and algorithms in surgical guidance and radiation oncology procedures. Especially, for the performance evaluation of new algorithms in the field of…

Quantitative metrics in lung computed tomography (CT) images have been widely used, often without a clear connection with physiology. This work proposes a patient-independent model for the estimation of well-aerated volume of lungs in CT…

Pulmonary hypertension (PH) can lead to significant vascular remodeling, resulting in altered pulmonary blood flow. Estimating the patient-specific contributions of each remodeling event is necessary to optimize and individualize clinical…

Biological Physics · Physics 2025-07-03 Sunder Neelakantan , Tanmay Mukherjee , Emilio A. Mendiola , Kyle Myers , Reza Avazmohammadi

The XCAT phantom is a realistic 4D digital torso phantom that is widely used in imaging and therapy research. However, lung mass is not conserved between respiratory phases of the phantom, making detailed dosimetric simulations and dose…

Background: Chronic obstructive pulmonary disease (COPD) is one of the most prevalent and dangerous pulmonary diseases in the world. It is forecasted that COPD will be the third deadly disease in the future. Therefore, developing…

Medical Physics · Physics 2016-05-30 Mohammad-Parsa Hosseini , Hamid Soltanian-Zadeh , Shahram Akhlaghpoor
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