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This paper addresses the problem of pathological lung segmentation, a significant challenge in medical image analysis, particularly pronounced in cases of peripheral opacities (severe fibrosis and consolidation) because of the textural…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Rezkellah Noureddine Khiati , Pierre-Yves Brillet , Aurélien Justet , Radu Ispas , Catalin Fetita

We conducted a multi-institutional audit of dosimetric variability between FLASH and conventional dose rate (CONV) electron irradiations by using an anatomically realistic 3D-printed mouse phantom. A CT scan of a live mouse was used to…

Purpose: Lymph nodes (LNs) in the chest have a tendency to enlarge due to various pathologies, such as lung cancer or pneumonia. Clinicians routinely measure nodal size to monitor disease progression, confirm metastatic cancer, and assess…

Image and Video Processing · Electrical Eng. & Systems 2024-01-15 Tejas Sudharshan Mathai , Bohan Liu , Ronald M. Summers

AI models for lung cancer screening are limited by data scarcity, impacting generalizability and clinical applicability. Generative models address this issue but are constrained by training data variability. We introduce SYN-LUNGS, a…

This work introduces a new latent diffusion model to generate high-quality 3D chest CT scans conditioned on 3D anatomical masks. The method synthesizes volumetric images of size 256x256x256 at 1 mm isotropic resolution using a single…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Anna Oliveras , Roger Marí , Rafael Redondo , Oriol Guardià , Ana Tost , Bhalaji Nagarajan , Carolina Migliorelli , Vicent Ribas , Petia Radeva

Many lung diseases require detailed visualisation for accurate diagnosis and treatment. High-resolution computed tomography (CT) is the gold-standard technique for non-invasive lung disease detection, but it presents a risk to the patient…

Lung mask creation lacks well-defined criteria and standardized guidelines, leading to a high degree of subjectivity between annotators. In this study, we assess the underestimation of lung regions on chest X-ray segmentation masks created…

This paper presents approaches to creating tissue mimicking materials that can be used as phantoms for evaluating the performance of Body Area Networks (BAN). The main goal of the paper is to describe a methodology to create a repeatable…

Signal Processing · Electrical Eng. & Systems 2018-06-13 Ahmed E. Khorshid , Ibrahim N. Alquaydheb , Ahmed M. Eltawil , Fadi J. Kurdahi

Interpreting quantitative CT biomarkers, such as organ volume and tissue attenuation, requires large-scale healthy reference distributions. However, creating these is challenging because clinical datasets are often heavily enriched with…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Christian Wachinger , Bernhard Renger , Christopher Späth , Jan Kirschke , Marcus Makowski

Recent studies have shown that lung cancer screening using annual low-dose computed tomography (CT) reduces lung cancer mortality by 20% compared to traditional chest radiography. Therefore, CT lung screening has started to be used widely…

Image and Video Processing · Electrical Eng. & Systems 2021-07-13 Gorkem Polat , Yesim Dogrusoz Serinagaoglu , Ugur Halici

Purpose: The XCAT phantom allows for highly sophisticated multimodality imaging research. It includes a complete set of organs, muscle, bone, soft tissue, while also accounting for age, sex, and body mass index (BMI), which allows phantom…

The airflow in a subject-specific breathing human lung is simulated with a multiscale computational fluid dynamics (CFD) lung model. The three-dimensional (3D) airway geometry beginning from the mouth to about 7 generations of airways is…

Fluid Dynamics · Physics 2013-10-21 Jiwoong Choi , Youbing Yin , Eric A. Hoffman , Merryn H. Tawhai , Ching-Long Lin

Accurate evaluation of regional lung ventilation is essential for the management and treatment of lung cancer patients, supporting assessments of pulmonary function, optimization of therapeutic strategies, and monitoring of treatment…

Medical Physics · Physics 2025-07-22 Rihui Zhang , Haiming Zhu , Jingtong Zhao , Lei Zhang , Fang-Fang Yin , Chunhao Wang , Zhenyu Yang

Non-invasive ventilation is increasingly used for respiratory support in preterm infants, and is associated with a lower risk of chronic lung disease. However, this mode is often not successful in the extremely preterm infant in part due to…

Tissues and Organs · Quantitative Biology 2018-07-04 Laura Ellwein Fix , Joseph Khoury , Russell Moores , Lauren Linkous , Matthew Brandes , Henry J. Rozycki

Propagation-based phase-contrast X-ray imaging is a promising technique for in~vivo medical imaging, offering lower radiation doses than traditional attenuation-based imaging. Previous studies have focused on X-ray energies below 50 keV for…

With the rapid development of artificial intelligence (AI), AI-assisted medical imaging analysis demonstrates remarkable performance in early lung cancer screening. However, the costly annotation process and privacy concerns limit the…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Yifan Jiang , Yannick Lemaréchal , Sophie Plante , Josée Bafaro , Jessica Abi-Rjeile , Philippe Joubert , Philippe Després , Venkata Manem

Analysis of chest CT scans can be used in detecting parts of lungs that are affected by infectious diseases such as COVID-19.Determining the volume of lungs affected by lesions is essential for formulating treatment recommendations and…

Pulmonary emphysema is traditionally subcategorized into three subtypes, which have distinct radiological appearances on computed tomography (CT) and can help with the diagnosis of chronic obstructive pulmonary disease (COPD). Automated…

Computer Vision and Pattern Recognition · Computer Science 2016-12-07 Jie Yang , Elsa D. Angelini , Benjamin M. Smith , John H. M. Austin , Eric A. Hoffman , David A. Bluemke , R. Graham Barr , Andrew F. Laine

Non-invasive estimation of respiratory physiology using computational algorithms promises to be a valuable technique for future clinicians to detect detrimental changes in patient pathophysiology. However, few clinical algorithms used to…

Quantitative Methods · Quantitative Biology 2021-09-22 Gregory Rehm , Jimmy Nguyen , Chelsea Gilbeau , Marc T Bomactao , Chen-Nee Chuah , Jason Adams

Reconstruction kernels in computed tomography (CT) affect spatial resolution and noise characteristics, introducing systematic variability in quantitative imaging measurements such as emphysema quantification. Choosing an appropriate kernel…