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Continuum bone remodelling is an important tool for predicting the effects of mechanical stimuli on bone density evolution. While the modelling of only cancellous bone is considered in many studies based on continuum bone remodelling, this…

Tissues and Organs · Quantitative Biology 2021-02-15 Ina Schmidt , Areti Papastavrou , Paul Steinmann

Multiscale topology optimization is crucial for designing porous infill structures with high stiffness-to-weight ratios and excellent energy absorption. Although gradient-based methods provide a rigorous framework, they are computationally…

Optimization and Control · Mathematics 2025-10-13 Shuzhi Xu , Yifan Guo , Hiroki Kawabe , Kentaro Yaji

Porous structures are materials consisting of minuscule pores, where the microstructure morphology significantly impacts their macroscopic properties. Integrating different porous structures through a blending method is indispensable to…

Graphics · Computer Science 2024-06-03 Depeng Gao , Yang Gao , Yuanzhi Zhang , Hongwei Lin

Model merging combines independent solutions with different capabilities into a single one while maintaining the same inference cost. Two popular approaches are linear interpolation, which simply averages multiple model weights, and task…

Machine Learning · Computer Science 2026-04-22 Chenxiang Zhang , Alexander Theus , Damien Teney , Antonio Orvieto , Jun Pang , Sjouke Mauw

Network optimization strategies for the process of synchronization have generally focused on the re-wiring or re-weighting of links in order to: (1) expand the range of coupling strengths that achieve synchronization, (2) expand the basin…

Adaptation and Self-Organizing Systems · Physics 2022-02-14 C. Tyler Diggans , Jeremie Fish , Abd AlRahman R. AlMomani , Erik M. Bollt

The dynamic behavior of microtubules in solution can be strongly modified by interactions with walls or other structures. We examine here a microtubule growth model where the increase in size of the plus-end is perturbed by collisions with…

Soft Condensed Matter · Physics 2010-09-29 Vladimir A. Baulin , Carlos M. Marques , Fabrice Thalmann

A multi-scale approach to the inverse reconstruction of a pattern's microstructure is reported. Instead of a correlation function, a pair of entropic descriptors (EDs) is proposed for stochastic optimization method. The first of them…

Statistical Mechanics · Physics 2011-02-16 R. Piasecki

Topology optimization of modular structures and mechanisms enables balancing the performance of automatically-generated individualized designs, as required by Industry 4.0, with enhanced sustainability by means of component reuse. For…

Materials Science · Physics 2022-05-25 Marek Tyburec , Martin Doškář , Jan Zeman , Martin Kružík

Open-porous scaffolds of WE43 Mg alloy with a body-center cubic cell pattern were manufactured by laser powder bed fusion with different strut diameters. The geometry of the unit cells was adequately reproduced during additive manufacturing…

Materials Science · Physics 2020-10-29 M. Li , F. Benn , T. Derra , N. Kroeger , M. Zinser , R. Smeets , J. M. Molina-Aldareguía , A. Kopp , J. LLorca

In this paper we address some modelling issues related to biological growth. Our treatment is based on a recently-proposed, general formulation for growth within the context of Mixture Theory (Journal of the Mechanics and Physics of Solids,…

Tissues and Organs · Quantitative Biology 2011-11-09 H. Narayanan , E. M. Arruda , K. Grosh , K. Garikipati

We propose a neural network-based computational framework for the simultaneous optimization of structural topology, curved layers, and path orientations to achieve strong anisotropic strength in fiber-reinforced thermoplastic composites…

Machine Learning · Computer Science 2025-05-08 Tao Liu , Tianyu Zhang , Yongxue Chen , Weiming Wang , Yu Jiang , Yuming Huang , Charlie C. L. Wang

Motivated by the large strain shear of loose granular materials we introduced a model which consists of consecutive optimization and restructuring steps leading to a self organization of a density field. The extensive connections to other…

Statistical Mechanics · Physics 2013-05-29 Janos Torok , Supriya Krishnamurthy , Janos Kertesz , Stephane Roux

We review microstructural fracture growth models suitable for the study of hydraulic fracture processes in disordered porous materials and present some basic results. It is shown that microstructural models exhibit certain similarities to…

Materials Science · Physics 2007-05-23 F. Tzschichholz , M. Wangen

We present a tool flow and results for a model-based hardware design for FPGAs from Simulink descriptions which nicely integrates into existing environments. While current commercial tools do not exploit some high-level optimizations, we…

Hardware Architecture · Computer Science 2015-08-28 Konrad Möller , Martin Kumm , Charles-Frederic Müller , Peter Zipf

We focused on polydimethylsiloxane (PDMS) as a substrate for replication, micropatterning, and construction of biologically active surfaces. The novelty of this study is based on the combina-tion of argon plasma exposure of micropatterned…

In this paper we present a simple microscopic stochastic model describing short term plasticity within a large homogeneous network of interacting neurons. Each neuron is represented by its membrane potential and by the residual calcium…

Probability · Mathematics 2020-01-29 Antonio Galves , Eva Löcherbach , Christophe Pouzat , Errico Presutti

The paper presents a new type of weakly nonlinear two-scale model of controllable periodic porous piezoelectric structures saturated by Newtonian fluids. The flow is propelled by peristaltic deformation of microchannels which is induced due…

Analysis of PDEs · Mathematics 2024-07-18 Eduard Rohan , Vladimír Lukeš

Remodelling of biological tissue, due to changes in microstructure, is treated in the continuum mechanical setting. Microstructural change is expressed as an evolution of the reference configuration. This evolution is expressed as a…

Quantitative Methods · Quantitative Biology 2007-05-23 K. Garikipati , H. Narayanan , E. M. Arruda , K. Grosh , S. Calve

Harmonic decomposition of surfaces, such as spherical and spheroidal harmonics, is used to analyze morphology, reconstruct, and generate surface inclusions of particulate microstructures. However, obtaining high-quality meshes of…

Graphics · Computer Science 2025-12-08 Mahmoud Shaqfa

Multiply connected freeform surface features are widely encountered in industrial components, where toolpath generation often suffers from discontinuities, sharp turns, non-uniform scallop heights, and incomplete boundary coverage. This…

Robotics · Computer Science 2026-04-27 Shen Changqing , Xu Bingzhou , Qi Bosong , Zhang Xiaojian , Yan Sijie , Ding Han
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