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Automated diagnosis based on color fundus photography is essential for large-scale glaucoma screening. However, existing deep learning models are typically data-driven and lack explicit integration of retinal anatomical knowledge, which…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Yuzhuo Zhou , Chi Liu , Sheng Shen , Zongyuan Ge , Fengshi Jing , Shiran Zhang , Yu Jiang , Anli Wang , Wenjian Liu , Feilong Yang , Tianqing Zhu , Xiaotong Han

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Vision-Language (VL) models have gained significant research focus, enabling remarkable advances in multimodal reasoning. These architectures typically comprise a vision encoder, a Large Language Model (LLM), and a projection module that…

Computer Vision and Pattern Recognition · Computer Science 2024-02-09 Roy Ganz , Yair Kittenplon , Aviad Aberdam , Elad Ben Avraham , Oren Nuriel , Shai Mazor , Ron Litman

We describe a new approach to automated Glaucoma detection in 3D Spectral Domain Optical Coherence Tomography (OCT) optic nerve scans. First, we gathered a unique and diverse multi-ethnic dataset of OCT scans consisting of glaucoma and…

Diabetic retinopathy (DR) is caused by long-standing diabetes and is among the fifth leading cause for visual impairments. The process of early diagnosis and treatments could be helpful in curing the disease, however, the detection…

Computer Vision and Pattern Recognition · Computer Science 2023-10-30 Chamuditha Jayanga Galappaththige , Gayal Kuruppu , Muhammad Haris Khan

Glaucomatous optic neuropathy (GON) is a prevalent ocular disease that can lead to irreversible vision loss if not detected early and treated. The traditional diagnostic approach for GON involves a set of ophthalmic examinations, which are…

Chart-based visual acuity measurements are used by billions of people to diagnose and guide treatment of vision impairment. However, the ubiquitous eye exam has no mechanism for reasoning about uncertainty and as such, suffers from a…

Artificial Intelligence · Computer Science 2019-11-25 Chris Piech , Ali Malik , Laura M Scott , Robert T Chang , Charles Lin

Differences in image quality, lighting conditions, and patient demographics pose challenges to automated glaucoma detection from color fundus photography. Brighteye, a method based on Vision Transformer, is proposed for glaucoma detection…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Hui Lin , Charilaos Apostolidis , Aggelos K. Katsaggelos

A surge of interest has emerged in utilizing Transformers in diverse vision tasks owing to its formidable performance. However, existing approaches primarily focus on optimizing internal model architecture designs that often entail…

Computer Vision and Pattern Recognition · Computer Science 2023-05-08 Lin Chen , Zhijie Jia , Tian Qiu , Lechao Cheng , Jie Lei , Zunlei Feng , Mingli Song

Vision Transformer(ViT) is one of the most widely used models in the computer vision field with its great performance on various tasks. In order to fully utilize the ViT-based architecture in various applications, proper visualization…

Computer Vision and Pattern Recognition · Computer Science 2024-02-08 Saebom Leem , Hyunseok Seo

Vision Transformer (ViT) has achieved outstanding results in computer vision. Although there are many Transformer-based architectures derived from the original ViT, the dimension of patches are often the same with each other. This…

Quantitative Methods · Quantitative Biology 2023-03-28 Takuma Usuzaki

Glaucoma is a leading cause of irreversible vision impairment globally and cases are continuously rising worldwide. Early detection is crucial, allowing timely intervention which can prevent further visual field loss. To detect glaucoma,…

Learning harmful shortcuts such as spurious correlations and biases prevents deep neural networks from learning the meaningful and useful representations, thus jeopardizing the generalizability and interpretability of the learned…

Computer Vision and Pattern Recognition · Computer Science 2022-05-26 Chong Ma , Lin Zhao , Yuzhong Chen , Lu Zhang , Zhenxiang Xiao , Haixing Dai , David Liu , Zihao Wu , Zhengliang Liu , Sheng Wang , Jiaxing Gao , Changhe Li , Xi Jiang , Tuo Zhang , Qian Wang , Dinggang Shen , Dajiang Zhu , Tianming Liu

Multimodal Large Language Models (MLLMs) excel in numerous vision-language tasks yet suffer from hallucinations, producing content inconsistent with input visuals, that undermine reliability in precision-sensitive domains. This issue stems…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Nan Sun , Zhenyu Zhang , Xixun Lin , Kun Wang , Yanmin Shang , Naibin Gu , Shuohuan Wang , Yu Sun , Hua Wu , Haifeng Wang , Yanan Cao

Glaucoma is the leading cause of irreversible but preventable blindness in the world. Its major treatable risk factor is the intra-ocular pressure, although other biomarkers are being explored to improve the understanding of the…

Computer Vision and Pattern Recognition · Computer Science 2018-10-26 José Ignacio Orlando , João Barbosa Breda , Karel van Keer , Matthew B. Blaschko , Pablo J. Blanco , Carlos A. Bulant

Multi-modal ophthalmic image classification plays a key role in diagnosing eye diseases, as it integrates information from different sources to complement their respective performances. However, recent improvements have mainly focused on…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Ke Zou , Tian Lin , Zongbo Han , Meng Wang , Xuedong Yuan , Haoyu Chen , Changqing Zhang , Xiaojing Shen , Huazhu Fu

Diabetic retinopathy (DR) is a leading cause of preventable blindness worldwide, demanding accurate automated diagnostic systems. While general-domain vision-language models like Contrastive Language-Image Pre-Training (CLIP) perform well…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Argha Kamal Samanta , Harshika Goyal , Vasudha Joshi , Tushar Mungle , Pabitra Mitra

Glaucoma is a progressive eye disease that leads to optic nerve damage, causing irreversible vision loss if left untreated. Optical coherence tomography (OCT) has become a crucial tool for glaucoma diagnosis, offering high-resolution 3D…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Roshan Kenia , Anfei Li , Rishabh Srivastava , Kaveri A. Thakoor

In this paper, we present a self-training-based framework for glaucoma grading using OCT B-scans under the presence of domain shift. Particularly, the proposed two-step learning methodology resorts to pseudo-labels generated during the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-24 Gabriel García , Adrián Colomer , Rafael Verdú-Monedero , José Dolz , Valery Naranjo

Recent progress in BIQA has been driven by VLMs, whose semantic reasoning abilities suggest that they might extract visual features, generate descriptive text, and infer quality in a human-like manner. However, these models often produce…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Yuan Li , Zitang Sun , Yen-ju Chen , Shin'ya Nishida
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