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Related papers: Discriminative protein sequence modelling with Lat…

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Variational Autoencoders for multimodal data hold promise for many tasks in data analysis, such as representation learning, conditional generation, and imputation. Current architectures either share the encoder output, decoder input, or…

Recently, self-supervised learning methods based on masked latent prediction have proven to encode input data into powerful representations. However, during training, the learned latent space can be further transformed to extract…

Sound · Computer Science 2025-06-05 Aurian Quelennec , Pierre Chouteau , Geoffroy Peeters , Slim Essid

Predicting the dynamics of complex systems is crucial for various scientific and engineering applications. The accuracy of predictions depends on the model's ability to capture the intrinsic dynamics. While existing methods capture key…

Computational Engineering, Finance, and Science · Computer Science 2025-06-10 Ruikun Li , Jingwen Cheng , Huandong Wang , Qingmin Liao , Yong Li

Recently several deep learning models have been used for DNA sequence based classification tasks. Often such tasks require long and variable length DNA sequences in the input. In this work, we use a sequence-to-sequence autoencoder model to…

Genomics · Quantitative Biology 2019-06-10 Vishal Agarwal , N Jayanth Kumar Reddy , Ashish Anand

Image generative models, particularly diffusion-based models, have surged in popularity due to their remarkable ability to synthesize highly realistic images. However, since these models are data-driven, they inherit biases from the…

Machine Learning · Computer Science 2025-03-18 Lin-Chun Huang , Ching Chieh Tsao , Fang-Yi Su , Jung-Hsien Chiang

A core problem in machine learning is to learn expressive latent variables for model prediction on complex data that involves multiple sub-components in a flexible and interpretable fashion. Here, we develop an approach that improves…

Machine Learning · Computer Science 2024-02-13 Yi-Lin Tuan , Zih-Yun Chiu , William Yang Wang

As the deep learning revolution marches on, self-supervised learning has garnered increasing attention in recent years thanks to its remarkable representation learning ability and the low dependence on labeled data. Among these varied…

Computer Vision and Pattern Recognition · Computer Science 2024-01-10 Siyuan Li , Luyuan Zhang , Zedong Wang , Di Wu , Lirong Wu , Zicheng Liu , Jun Xia , Cheng Tan , Yang Liu , Baigui Sun , Stan Z. Li

We introduce a novel latent vector space model that jointly learns the latent representations of words, e-commerce products and a mapping between the two without the need for explicit annotations. The power of the model lies in its ability…

Information Retrieval · Computer Science 2016-08-26 Christophe Van Gysel , Maarten de Rijke , Evangelos Kanoulas

Augmentation for dense prediction typically relies on either sample mixing or generative synthesis. Mixing improves robustness but misaligned masks yield soft label ambiguity. Diffusion synthesis increases apparent diversity but, when…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Pengyu Jie , Wanquan Liu , Rui He , Yihui Wen , Deyu Meng , Chenqiang Gao

Protein language models (PLMs) have revolutionised computational biology through their ability to generate powerful sequence representations for diverse prediction tasks. However, their black-box nature limits biological interpretation and…

Biomolecules · Quantitative Biology 2025-04-11 Jan van Eck , Dea Gogishvili , Wilson Silva , Sanne Abeln

Self-supervised representation learning has gained increasing attention for strong generalization ability without relying on paired datasets. However, it has not been explored sufficiently for facial representation. Self-supervised facial…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Ruian He , Zhen Xing , Weimin Tan , Bo Yan

Geometric deep learning has recently achieved great success in non-Euclidean domains, and learning on 3D structures of large biomolecules is emerging as a distinct research area. However, its efficacy is largely constrained due to the…

Machine Learning · Computer Science 2023-10-31 Fang Wu , Lirong Wu , Dragomir Radev , Jinbo Xu , Stan Z. Li

Deep neural-network-based language models (LMs) are increasingly applied to large-scale protein sequence data to predict protein function. However, being largely black-box models and thus challenging to interpret, current protein LM…

Quantitative Methods · Quantitative Biology 2024-08-06 Mai Ha Vu , Rahmad Akbar , Philippe A. Robert , Bartlomiej Swiatczak , Victor Greiff , Geir Kjetil Sandve , Dag Trygve Truslew Haug

The need for a large amount of labeled data in the supervised setting has led recent studies to utilize self-supervised learning to pre-train deep neural networks using unlabeled data. Many self-supervised training strategies have been…

Computer Vision and Pattern Recognition · Computer Science 2022-04-06 Mojtaba Bahrami , Mahsa Ghorbani , Nassir Navab

Recent progress in imitation learning has been enabled by policy architectures that scale to complex visuomotor tasks, multimodal distributions, and large datasets. However, these methods often rely on learning from large amount of expert…

Robotics · Computer Science 2025-04-24 Amber Xie , Oleh Rybkin , Dorsa Sadigh , Chelsea Finn

There have been recent efforts to learn more meaningful representations via fixed length codewords from mesh data, since a mesh serves as a complete model of underlying 3D shape compared to a point cloud. However, the mesh connectivity…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Eric Lei , Muhammad Asad Lodhi , Jiahao Pang , Junghyun Ahn , Dong Tian

Masked Diffusion Models (MDMs) have emerged as one of the most promising paradigms for generative modeling over discrete domains. It is known that MDMs effectively train to decode tokens in a random order, and that this ordering has…

Machine Learning · Computer Science 2025-11-25 Prateek Garg , Bhavya Kohli , Sunita Sarawagi

Face anonymization aims to conceal identity information while preserving non-identity attributes. Mainstream diffusion models rely on inference-time interventions such as negative guidance or energy-based optimization, which are applied…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Haoxin Yang , Yihong Lin , Jingdan Kang , Xuemiao Xu , Yue Li , Cheng Xu , Shengfeng He

Motivation: Human genomic datasets often contain sensitive information that limits use and sharing of the data. In particular, simple anonymisation strategies fail to provide sufficient level of protection for genomic data, because the data…

Quantitative Methods · Quantitative Biology 2019-08-27 Teppo Niinimäki , Mikko Heikkilä , Antti Honkela , Samuel Kaski

Proteins are essential macromolecules defined by their amino acid sequences, which determine their three-dimensional structures and, consequently, their functions in all living organisms. Therefore, generative protein modeling necessitates…

Machine Learning · Computer Science 2024-10-18 Xinyou Wang , Zaixiang Zheng , Fei Ye , Dongyu Xue , Shujian Huang , Quanquan Gu
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