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Artificial intelligence (AI) agents are emerging as transformative tools in drug discovery, with the ability to autonomously reason, act, and learn through complicated research workflows. Building on large language models (LLMs) coupled…

We explore the potential for productive team-based collaboration between humans and Artificial Intelligence (AI) by presenting and conducting initial tests with a general framework that enables multiple human and AI agents to work together…

Human-Computer Interaction · Computer Science 2024-12-04 Benjamin Klieger , Charis Charitsis , Miroslav Suzara , Sierra Wang , Nick Haber , John C. Mitchell

Recent advances in AI agents for software engineering and scientific discovery have demonstrated remarkable capabilities, yet their application to developing novel ranking models in commercial search engines remains unexplored. In this…

Information Retrieval · Computer Science 2026-03-25 Liwei Wu , Cho-Jui Hsieh

With automated systems increasingly issuing search queries alongside humans, Information Retrieval (IR) faces a major shift. Yet IR remains human-centred, with systems, evaluation metrics, user models, and datasets designed around human…

Information Retrieval · Computer Science 2026-02-20 Francesca Pezzuti , Ophir Frieder , Fabrizio Silvestri , Sean MacAvaney , Nicola Tonellotto

Recently, there has been an emergence of employing LLM-powered agents as believable human proxies, based on their remarkable decision-making capability. However, existing studies mainly focus on simulating human dialogue. Human non-verbal…

Information Retrieval · Computer Science 2023-10-16 Junjie Zhang , Yupeng Hou , Ruobing Xie , Wenqi Sun , Julian McAuley , Wayne Xin Zhao , Leyu Lin , Ji-Rong Wen

Deep research systems powered by LLM agents have transformed complex information seeking by automating the iterative retrieval, filtering, and synthesis of insights from massive-scale web sources. However, existing systems predominantly…

Information Retrieval · Computer Science 2026-03-16 Bo Pan , Lunke Pan , Yitao Zhou , Qi Jiang , Zhen Wen , Minfeng Zhu , Wei Chen

The rise of multi-agent systems powered by large language models (LLMs) and specialized reasoning agents exposes fundamental limitations in today's data management architectures. Traditional databases and data fabrics were designed for…

Multiagent Systems · Computer Science 2025-12-11 Ioana Giurgiu , Michael E. Nidd

Recent advances in large language models (LLMs) have enabled the development of AI agents that exhibit increasingly human-like behaviors, including planning, adaptation, and social dynamics across diverse, interactive, and open-ended…

Neurons and Cognition · Quantitative Biology 2025-06-13 Lin Chen , Yunke Zhang , Jie Feng , Haoye Chai , Honglin Zhang , Bingbing Fan , Yibo Ma , Shiyuan Zhang , Nian Li , Tianhui Liu , Nicholas Sukiennik , Keyu Zhao , Yu Li , Ziyi Liu , Fengli Xu , Yong Li

With the recent development of natural language generation models - termed as large language models (LLMs) - a potential use case has opened up to improve the way that humans interact with robot assistants. These LLMs should be able to…

Multiagent Systems · Computer Science 2024-11-27 Mitchell Rosser , Marc. G Carmichael

We define Agency as the emergent capacity of AI systems to function as autonomous agents actively discovering problems, formulating hypotheses, and executing solutions through self-directed engagement with environments and tools. This…

In the age of large language models (LLMs), autonomous agents have emerged as a powerful paradigm for achieving general intelligence. These agents dynamically leverage tools, memory, and reasoning capabilities to accomplish user-defined…

Artificial Intelligence · Computer Science 2025-08-05 Chaojia Yu , Zihan Cheng , Hanwen Cui , Yishuo Gao , Zexu Luo , Yijin Wang , Hangbin Zheng , Yong Zhao

Artificial Intelligence (AI) is accelerating the transformation of scientific research paradigms, not only enhancing research efficiency but also driving innovation. We introduce InternAgent, a unified closed-loop multi-agent framework to…

For a long time, humanity has pursued artificial intelligence (AI) equivalent to or surpassing the human level, with AI agents considered a promising vehicle for this pursuit. AI agents are artificial entities that sense their environment,…

Agentic AI represents a major shift in how autonomous systems reason, plan, and execute multi-step tasks through the coordination of Large Language Models (LLMs), Vision Language Models (VLMs), tools, and external services. While these…

The increasing realism of AI-Generated Images (AIGI) has created an urgent need for forensic tools capable of reliably distinguishing synthetic content from authentic imagery. Existing detectors are typically tailored to specific forgery…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Yangxin Yu , Yue Zhou , Bin Li , Kaiqing Lin , Haodong Li , Jiangqun Ni , Bo Cao

The advancements of large language models (LLMs) have piqued growing interest in developing LLM-based language agents to automate scientific discovery end-to-end, which has sparked both excitement and skepticism about their true…

Drug discovery frequently loses momentum when data, expertise, and tools are scattered, slowing design cycles. To shorten this loop we built a hierarchical, tool using agent framework that automates molecular optimisation. A Principal…

Machine Learning · Computer Science 2025-08-06 Atabey Ünlü , Phil Rohr , Ahmet Celebi

As scientific research becomes increasingly complex, innovative tools are needed to manage vast data, facilitate interdisciplinary collaboration, and accelerate discovery. Large language models (LLMs) are now evolving into LLM-based…

Artificial Intelligence · Computer Science 2026-02-03 Shuo Ren , Can Xie , Pu Jian , Zhenjiang Ren , Chunlin Leng , Jiajun Zhang

Agent self-improvement, where the backbone Large Language Model (LLM) of the agent are trained on trajectories sampled autonomously based on their own policies, has emerged as a promising approach for enhancing performance. Recent…

Computation and Language · Computer Science 2025-08-22 Tianqing Fang , Hongming Zhang , Zhisong Zhang , Kaixin Ma , Wenhao Yu , Haitao Mi , Dong Yu

Large language models (LLMs) are increasingly deployed as AI agents that operate in short reasoning-action loops, interleaving model computation with external calls. Unlike traditional chat applications, these agentic workloads require…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-12 Yuning Zhang , Yan Yan , Nan Yang , Dong Yuan
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