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In recent years, machine learning models have been increasingly applied to spectroscopic datasets for chemical and biomedical analysis. For their successful adoption, particularly in clinical and safety-critical settings, professionals and…

Interpretable machine learning is essential in high-stakes domains where decision-making requires accountability, transparency, and trust. While rule-based models offer global and exact interpretability, learning rule sets that…

Machine Learning · Computer Science 2026-03-10 Hans Farrell Soegeng , Sarthak Ketanbhai Modi , Thomas Peyrin

Interpretability is a pressing issue for machine learning. Common approaches to interpretable machine learning constrain interactions between features of the input, rendering the effects of those features on a model's output comprehensible…

Machine Learning · Computer Science 2023-05-11 Kieran A. Murphy , Dani S. Bassett

In data-driven applications relying on tabular data, where interpretability is key, machine learning models such as decision trees and linear regression are applied. Although neural networks can provide higher predictive performance, they…

Machine Learning · Computer Science 2026-03-30 Khawla Elhadri , Jörg Schlötterer , Christin Seifert

Sparse Autoencoders (SAEs) are a prominent tool in mechanistic interpretability (MI) for decomposing neural network activations into interpretable features. However, the aspiration to identify a canonical set of features is challenged by…

Machine Learning · Computer Science 2025-05-27 Xiangchen Song , Aashiq Muhamed , Yujia Zheng , Lingjing Kong , Zeyu Tang , Mona T. Diab , Virginia Smith , Kun Zhang

Decision-making in complex systems often relies on machine learning models, yet highly accurate models such as XGBoost and neural networks can obscure the reasoning behind their predictions. In operations research applications,…

Machine Learning · Computer Science 2025-02-28 Gaurav Arwade , Sigurdur Olafsson

Learning from complex real-life networks is a lively research area, with recent advances in learning information-rich, low-dimensional network node representations. However, state-of-the-art methods are not necessarily interpretable and are…

Machine Learning · Computer Science 2020-12-01 Sebastian Mežnar , Nada Lavrač , Blaž Škrlj

Automatic feature engineering is an effective approach for improving predictive performance in tabular learning. However, expand-and-reduce methods, such as OpenFE, become increasingly computationally expensive as the input dimensionality…

Machine Learning · Statistics 2026-05-01 Minhee Park , Seongyeon Son , Yonghyun Lee , Eunchan Kim

A new line of research for feature selection based on neural networks has recently emerged. Despite its superiority to classical methods, it requires many training iterations to converge and detect informative features. The computational…

Machine Learning · Computer Science 2022-11-29 Ghada Sokar , Zahra Atashgahi , Mykola Pechenizkiy , Decebal Constantin Mocanu

Sparse principal component analysis (SPCA) has emerged as a powerful technique for modern data analysis, providing improved interpretation of low-rank structures by identifying localized spatial structures in the data and disambiguating…

Many current state-of-the-art models for sequential recommendations are based on transformer architectures. Interpretation and explanation of such black box models is an important research question, as a better understanding of their…

Information Retrieval · Computer Science 2026-02-18 Anton Klenitskiy , Konstantin Polev , Daria Denisova , Alexey Vasilev , Dmitry Simakov , Gleb Gusev

Sparse Autoencoders (SAEs) have proven to be powerful tools for interpreting neural networks by decomposing hidden representations into disentangled, interpretable features via sparsity constraints. However, conventional SAEs are…

RFdiffusion is a popular and well-established model for generation of protein structures. However, this generative process offers limited insight into its internal representations and how they contribute to the final protein structure.…

Quantitative Methods · Quantitative Biology 2025-12-01 Wojciech Zarzecki , Paulina Szymczak , Ewa Szczurek , Kamil Deja

Despite the ubiquity of tabular data in high-stakes domains, traditional deep learning architectures often struggle to match the performance of gradient-boosted decision trees while maintaining scientific interpretability. Standard neural…

Machine Learning · Computer Science 2026-01-29 Fang Li

Real-world tabular databases routinely combine continuous measurements and categorical records, yet missing entries are pervasive and can distort downstream analysis. We propose Statistical-Neural Interaction (SNI), an interpretable…

Machine Learning · Computer Science 2026-01-21 Ou Deng , Shoji Nishimura , Atsushi Ogihara , Qun Jin

With the growing pervasiveness of artificial intelligence, the ability to explain the inferences made by machine learning models has become increasingly important. Numerous techniques for model explainability have been proposed, with…

Human-Computer Interaction · Computer Science 2026-04-08 Nicola Rossberg , Bennett Kleinberg , Barry O'Sullivan , Luca Longo , Andrea Visentin

A central goal for mechanistic interpretability has been to identify the right units of analysis in large language models (LLMs) that causally explain their outputs. While early work focused on individual neurons, evidence that neurons…

Computation and Language · Computer Science 2026-05-05 Or Shafran , Atticus Geiger , Mor Geva

Sparse autoencoders (SAEs) extract millions of interpretable features from a language model, but flat feature inventories aren't very useful on their own. Domain concepts get mixed with generic and weakly grounded features, while related…

Artificial Intelligence · Computer Science 2026-04-29 John Winnicki , Abeynaya Gnanasekaran , Eric Darve

We introduce a new approach to systematically map features discovered by sparse autoencoder across consecutive layers of large language models, extending earlier work that examined inter-layer feature links. By using a data-free cosine…

Machine Learning · Computer Science 2025-07-28 Daniil Laptev , Nikita Balagansky , Yaroslav Aksenov , Daniil Gavrilov

Disentangling model activations into meaningful features is a central problem in interpretability. However, the absence of ground-truth for these features in realistic scenarios makes validating recent approaches, such as sparse dictionary…

Machine Learning · Computer Science 2024-05-21 Aleksandar Makelov , George Lange , Neel Nanda
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