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The goal of this paper is to present an end-to-end, data-driven framework to control Autonomous Mobility-on-Demand systems (AMoD, i.e. fleets of self-driving vehicles). We first model the AMoD system using a time-expanded network, and…

Robotics · Computer Science 2017-09-22 Ramon Iglesias , Federico Rossi , Kevin Wang , David Hallac , Jure Leskovec , Marco Pavone

In this paper, we build a new, simple, and interpretable mathematical model to estimate and forecast physiology related to the human glucose-insulin system, constrained by available data. By constructing a simple yet flexible model class…

Quantitative Methods · Quantitative Biology 2022-09-22 M. Sirlanci , M. E. Levine , C. C. Low Wang , D. J. Albers , A. M. Stuart

In many forecasting applications, it is valuable to predict not only the value of a signal at a certain time point in the future, but also the values leading up to that point. This is especially true in clinical applications, where the…

Machine Learning · Computer Science 2019-04-09 Ian Fox , Lynn Ang , Mamta Jaiswal , Rodica Pop-Busui , Jenna Wiens

We present GlucOS, a novel system for trustworthy automated insulin delivery. Fundamentally, this paper is about a system we designed, implemented, and deployed on real humans and the lessons learned from our experiences. GlucOS introduces…

Cryptography and Security · Computer Science 2025-10-28 Hari Venugopalan , Shreyas Madhav Ambattur Vijayanand , Caleb Stanford , Stephanie Crossen , Samuel T. King

High quality real world datasets are essential for advancing data driven approaches in type 1 diabetes (T1D) management, including personalized therapy design, digital twin systems, and glucose prediction models. However, progress in this…

Machine Learning · Computer Science 2025-06-19 Saman Khamesian , Asiful Arefeen , Bithika M. Thompson , Maria Adela Grando , Hassan Ghasemzadeh

This study develops a cloud-based deep learning system for early prediction of diabetes, leveraging the distributed computing capabilities of the AWS cloud platform and deep learning technologies to achieve efficient and accurate risk…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-01-07 Yang Zhang , Fa Wang , Xin Huang , Xintao Li , Sibei Liu , Hansong Zhang

The Internet of Things (IoT) revolutionizes smart city domains such as healthcare, transportation, industry, and education. The Internet of Medical Things (IoMT) is gaining prominence, particularly in smart hospitals and Remote Patient…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-25 Alain Hennebelle , Qifan Dieng , Leila Ismail , Rajkumar Buyya

The global prevalence of diabetes, particularly type 2 diabetes mellitus (T2DM), is rapidly increasing, posing significant health and economic challenges. T2DM not only disrupts blood glucose regulation but also damages vital organs such as…

Machine Learning · Computer Science 2025-06-09 Praveen Kumar , Vincent T. Metzger , Scott A. Malec

Model Predictive Control (MPC) provides an optimal control solution based on a cost function while allowing for the implementation of process constraints. As a model-based optimal control technique, the performance of MPC strongly depends…

Systems and Control · Electrical Eng. & Systems 2024-09-11 David C. Gordon , Alexander Winkler , Julian Bedei , Patrick Schaber , Jakob Andert , Charles R. Koch

This paper presents the Derivatives Combination Predictor (DCP), a novel model fusion algorithm for making long-term glucose predictions for diabetic people. First, using the history of glucose predictions made by several models, the future…

Quantitative Methods · Quantitative Biology 2020-09-10 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

Comorbid chronic conditions are common among people with type 2 diabetes. We developed an Artificial Intelligence algorithm, based on Reinforcement Learning (RL), for personalized diabetes and multi-morbidity management with strong…

Computers and Society · Computer Science 2020-11-05 Hua Zheng , Ilya O. Ryzhov , Wei Xie , Judy Zhong

While the Artificial Pancreas is effective in regulating the blood glucose in the safe range of 70-180 mg/dl in type 1 diabetic patients, the high intra-patient variability, as well as exogenous meal disturbances, poses a serious challenge.…

Systems and Control · Electrical Eng. & Systems 2022-06-30 Bhabani Shankar Dey , Anirudh Nath , Abhilash Patel , Indra Narayan Kar

Type 1 Diabetes (T1D) is a chronic condition where the body produces little or no insulin, a hormone required for the cells to use blood glucose (BG) for energy and to regulate BG levels in the body. Finding the right insulin dose and time…

Machine Learning · Computer Science 2024-11-28 Isabella Degen , Zahraa S. Abdallah

Effective dietary monitoring is critical for managing Type 2 diabetes, yet accurately estimating caloric intake remains a major challenge. While continuous glucose monitors (CGMs) offer valuable physiological data, they often fall short in…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Adarsh Kumar

Blood glucose simulation allows the effectiveness of type 1 diabetes (T1D) management strategies to be evaluated without patient harm. Deep learning algorithms provide a promising avenue for extending simulator capabilities; however, these…

Machine Learning · Computer Science 2023-10-24 Harry Emerson , Ryan McConville , Matthew Guy

We develop a three-component Model Predictive Control (MPC) algorithm to achieve output-reference tracking with prescribed performance for continuous-time nonlinear systems. One component is so-called funnel MPC, which achieves reference…

Optimization and Control · Mathematics 2025-02-18 Lukas Lanza , Dario Dennstädt , Thomas Berger , Karl Worthmann

Describing dynamic medical systems using machine learning is a challenging topic with a wide range of applications. In this work, the possibility of modeling the blood glucose level of diabetic patients purely on the basis of measured data…

Machine Learning · Computer Science 2023-03-10 David Jödicke , Daniel Parra , Gabriel Kronberger , Stephan Winkler

This paper considers the problem of supply-demand imbalances in Mobility-on-Demand (MoD) services, such as Uber or DiDi Rider. Such imbalances are due to uneven stochastic travel demand and can be prevented by proactively rebalance empty…

Systems and Control · Electrical Eng. & Systems 2023-01-18 Sten Elling Tingstad Jacobsen , Anders Lindman , Balázs Kulcsár

Intelligent learning diagnosis is a critical engine of intelligent tutoring systems, which aims to estimate learners' current knowledge mastery status and predict their future learning performance. The significant challenge with traditional…

Artificial Intelligence · Computer Science 2023-06-14 Zhifeng Wang , Wenxing Yan , Chunyan Zeng , Shi Dong

Adherence to prescribed treatments is crucial for individuals with chronic conditions to avoid costly or adverse health outcomes. For certain patient groups, intensive lifestyle interventions are vital for enhancing medication adherence.…

Machine Learning · Computer Science 2025-03-21 Abdullah Mamun , Diane J. Cook , Hassan Ghasemzadeh
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