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Radiation therapy treatment planning is an iterative, expertise-dependent process, and the growing burden of cancer cases has made reliance on manual planning increasingly unsustainable, underscoring the need for automation. In this study,…

Medical Physics · Physics 2025-10-15 Dongrong Yang , Xin Wu , Yibo Xie , Xinyi Li , Qiuwen Wu , Jackie Wu , Yang Sheng

Generating physician letters is a time-consuming task in daily clinical practice. This study investigates local fine-tuning of large language models (LLMs), specifically LLaMA models, for physician letter generation in a privacy-preserving…

Stereotactic radiosurgery (SRS) demands precise dose shaping around critical structures, yet black-box AI systems have limited clinical adoption due to opacity concerns. We tested whether chain-of-thought reasoning improves agentic planning…

Large language model (LLM) agents have demonstrated remarkable capabilities in tool use, reasoning, and code generation, yet single-agent systems exhibit fundamental limitations when confronted with complex research tasks demanding…

Artificial Intelligence · Computer Science 2026-03-17 Aaron Shen , Alfred Shen

Running Large Language Models (LLMs) on edge devices is constrained by high compute and memory demands posing a barrier for real-time applications in sectors like healthcare, education, and embedded systems. Current solutions such as…

Large language models (LLMs) have emerged as valuable tools for many natural language understanding tasks. In safety-critical applications such as healthcare, the utility of these models is governed by their ability to generate outputs that…

Computation and Language · Computer Science 2023-03-31 Varun Nair , Elliot Schumacher , Geoffrey Tso , Anitha Kannan

Direct Preference Optimization (DPO) has shown effectiveness in aligning multi-modal large language models (MLLM) with human preferences. However, existing methods exhibit an imbalanced responsiveness to the data of varying hardness,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-12 Jinda Lu , Junkang Wu , Jinghan Li , Xiaojun Jia , Shuo Wang , YiFan Zhang , Junfeng Fang , Xiang Wang , Xiangnan He

Purpose: To develop a retrieval-augmented generation (RAG) system powered by LLaMA-4 109B for automated, protocol-aware, and interpretable evaluation of radiotherapy treatment plans. Methods and Materials: We curated a multi-protocol…

Large Language Models (LLMs) demonstrate strong generalization and reasoning abilities, making them well-suited for complex decision-making tasks such as medical consultation (MC). However, existing LLM-based methods often fail to capture…

Computation and Language · Computer Science 2025-10-13 Zhihao Jia , Mingyi Jia , Junwen Duan , Jianxin Wang

Pathology reports serve as the definitive record for breast cancer staging, yet their unstructured format impedes large-scale data curation. While Large Language Models (LLMs) offer semantic reasoning, their deployment is often limited by…

Machine Learning · Computer Science 2026-04-16 Jiahao Shao , Anam Nawaz Khan , Christopher Brett , Tom Berg , Xueping Li , Bing Yao

The rapid integration of Large Language Model (LLM) agents into autonomous task execution has introduced significant privacy concerns within cross-tool data flows. In this paper, we systematically investigate and define a novel risk termed…

Software Engineering · Computer Science 2026-03-10 Yixi Lin , Jiangrong Wu , Yuhong Nan , Xueqiang Wang , Xinyuan Zhang , Zibin Zheng

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

To develop an automated workflow for rectal cancer three-dimensional conformal radiotherapy treatment planning that combines deep-learning(DL) aperture predictions and forward-planning algorithms. We designed an algorithm to automate the…

Optimizing the advertiser's cumulative value of winning impressions under budget constraints poses a complex challenge in online advertising, under the paradigm of AI-Generated Bidding (AIGB). Advertisers often have personalized objectives…

Artificial Intelligence · Computer Science 2026-01-22 Mingxuan Song , Yusen Huo , Bohan Zhou , Shenglin Yin , Zhen Xiao , Jieyi Long , Zhilin Zhang , Chuan Yu

The massive successes of large language models (LLMs) encourage the emerging exploration of LLM-augmented Autonomous Agents (LAAs). An LAA is able to generate actions with its core LLM and interact with environments, which facilitates the…

Treatment planning is currently a patient specific, time-consuming, and resource demanding task in radiotherapy. Dose-volume histogram (DVH) prediction plays a critical role in automating this process. The geometric relationship between…

Artificial Intelligence · Computer Science 2024-02-13 Zehao Dong , Yixin Chen , Hiram Gay , Yao Hao , Geoffrey D. Hugo , Pamela Samson , Tianyu Zhao

Recent advances in large language models (LLMs) have sparked growing interest in automatic RTL optimization for better performance, power, and area (PPA). However, existing methods are still far from realistic RTL optimization. Their…

Artificial Intelligence · Computer Science 2026-04-28 Wenji Fang , Yao Lu , Shang Liu , Jing Wang , Ziyan Guo , Junxian He , Fengbin Tu , Zhiyao Xie

Large Language Models (LLMs) can be fine-tuned on domain-specific data to enhance their performance in specialized fields. However, such data often contains numerous low-quality samples, necessitating effective data processing (DP). In…

Machine Learning · Computer Science 2026-05-08 Wei Huang , Anda Cheng , Yinggui Wang , Lei Wang , Tao Wei

Despite the promise of Vision-Language-Action (VLA) models as generalist robotic controllers, their robustness against perceptual noise and environmental variations in out-of-distribution (OOD) tasks remains fundamentally limited by the…

Robotics · Computer Science 2026-03-30 Zhuoran Li , Zhiyang Li , Kaijun Zhou , Jinyu Gu

Answering Questions over Knowledge Graphs (KGQA) is key to well-functioning autonomous language agents in various real-life applications. To improve the neural-symbolic reasoning capabilities of language agents powered by Large Language…

Computation and Language · Computer Science 2024-06-12 Haishuo Fang , Xiaodan Zhu , Iryna Gurevych
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