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E. coli bacteria swim following a run and tumble pattern. In the run state all flagella join in a single helical bundle that propels the cell body along approximately straight paths. When one or more flagellar motors reverse direction the…

Soft Condensed Matter · Physics 2015-07-01 S. Bianchi , F. Saglimbeni , A. Lepore , R. Di Leonardo

The run-and-tumble dynamics of bacteria, as exhibited by \textit{E. coli}, offers a simple experimental realization of non-Brownian, yet diffusive, particles. Here we present some analytic and numerical results for models of the ideal…

Statistical Mechanics · Physics 2009-08-12 J. Tailleur , M. E. Cates

We consider the lateral diffusion of a protein interacting with the curvature of the membrane. The interaction energy is minimized if the particle is at a membrane position with a certain curvature that agrees with the spontaneous curvature…

Soft Condensed Matter · Physics 2008-12-10 Stefan M. Leitenberger , Ellen Reister-Gottfried , Udo Seifert

Recent research has shown that motile cells can adapt their mode of propulsion to the mechanical properties of the environment in which they find themselves--crawling in some environments while swimming in others. The latter can involve…

Biological Physics · Physics 2018-05-24 Hao Wu , Marco Avila Ponce de Leon , Hans G. Othmer

Recent experiments have illuminated a remarkable growth mechanism of rod-shaped bacteria: proteins associated with cell wall extension move at constant velocity in circles oriented approximately along the cell circumference (Garner et al.,…

Biological Physics · Physics 2013-05-15 Ariel Amir , David R. Nelson

Microswimmers exhibit more diverse behavior in quasi-two dimensions than in three dimensions. Such behavior remains elusive due to the analytical difficulty of dealing with two parallel solid boundaries. The existence of additional…

Soft Condensed Matter · Physics 2023-01-18 Yuki Takaha , Daiki Nishiguchi

Centrifugation is a widespread laboratory technique used to separate mixtures into fractions characterized by a specific size, weight or density. We demonstrate that centrifugation can be also used to separate swimming cells having…

Soft Condensed Matter · Physics 2014-11-07 Claudio Maggi , Alessia Lepore , Jacopo Solari , Alessandro Rizzo , Roberto Di Leonardo

We numerically study the dynamics of run-and-tumble particles confined in two chambers connected by thin channels. Two dominant dynamical behaviors emerge: (i) an oscillatory pumping state, in which particles periodically fill the two…

Soft Condensed Matter · Physics 2015-11-04 M. Paoluzzi , R. Di Leonardo , L. Angelani

Run-and-tumble is a common but vital strategy that bacteria employ to explore environment suffused with boundaries, as well as to escape from entrapment. In this study we reveal how this strategy and the resulting dynamical behavior can be…

Soft Condensed Matter · Physics 2025-01-30 Premkumar Leishangthem , Xuan Wang , Junan Chen , Shengqi Yang , Xinliang Xu

In natural environments, solid surfaces present both opportunities and challenges for bacteria. On one hand, they serve as platforms for biofilm formation, crucial for bacterial colonization and resilience in harsh conditions. On the other…

Biological Physics · Physics 2025-07-01 Antai Tao , Guangzhe Liu , Rongjing Zhang , Junhua Yuan

The interaction of surfaces in relative motion in wet environments is dominated by lubrication forces, which play a pivotal role in the dynamics of microscopic systems. Here, we develop motile vesicles that exploit lubrication forces to…

One striking feature of bacterial motion is their ability to swim upstream along corners and crevices, by leveraging hydrodynamic interactions. This motion through anatomic ducts or medical devices might be at the origin of serious…

Soft Condensed Matter · Physics 2020-04-07 Nuris Figueroa-Morales , Aramis Rivera , Rodrigo Soto , Anke Lindner , Ernesto Altshuler , Eric Clement

Active systems comprised of self-propelled units show fascinating transitions from Brownian-like dynamics to collective coherent motion. Swirling of swimming bacteria is a spectacular example. This study demonstrates that a nematic liquid…

Confinement and wall effects are known to affect the kinematics and propulsive characteristics of swimming microorganisms. When a solid body is dragged through a viscous fluid at constant velocity, the presence of a wall increases fluid…

Biological Physics · Physics 2010-10-29 Arthur A. Evans , Eric Lauga

Flagellated bacteria are hydrodynamically attracted to rigid walls, yet past work shows a 'hovering' state where they swim stably at a finite height above surfaces. We use numerics and theory to reveal the physical origin of hovering.…

Biological Physics · Physics 2024-09-17 Pyae Hein Htet , Debasish Das , Eric Lauga

We present a simple model for bacteria like \emph{Escherichia coli} swimming near solid surfaces. It consists of two spheres of different radii connected by a dragless rod. The effect of the flagella is taken into account by imposing a…

Fluid Dynamics · Physics 2015-06-03 Jocelyn Dunstan , Gastón Miño , Eric Clement , Rodrigo Soto

Biological membranes are shaped by various proteins that either generate inward or outward membrane curvature. In this article, we investigate the membrane morphologies induced by mixtures of arc-shaped particles with coarse-grained…

Subcellular Processes · Quantitative Biology 2020-04-03 Francesco Bonazzi , Carol K. Hall , Thomas R. Weikl

We demonstrate with experiments and simulations how microscopic self-propelled particles navigate through environments presenting complex spatial features, which mimic the conditions inside cells, living organisms and future lab-on-a-chip…

Biological Physics · Physics 2011-09-22 Giovanni Volpe , Ivo Buttinoni , Dominik Vogt , Hans-Juergen Kuemmerer , Clemens Bechinger

Microswimmers such as E. Coli bacteria accumulate and exhibit an intriguing dynamics near walls, governed by hydrodynamic and steric interactions. Insight into the underlying mechanisms and predominant interactions demand a detailed…

Soft Condensed Matter · Physics 2020-07-03 S. Mahdiyeh Mousavi , Gerhard Gompper , Roland G. Winkler

In a classic paper, Edward Purcell analysed the dynamics of flagellated bacterial swimmers and derived a geometrical relationship which optimizes the propulsion efficiency. Experimental measurements for wild-type bacterial species E. coli…

Biological Physics · Physics 2020-01-08 Praneet Prakash , Amith Z. Abdulla , Varsha Singh , Manoj Varma