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Related papers: APPA : Agentic Preformulation Pathway Assistant

200 papers

Autoresearch offers a flexible paradigm for automating scientific tasks, in which an AI agent proposes, implements, evaluates, and refines candidate solutions against a quantitative objective. Here, we use composition-based…

Materials Science · Physics 2026-05-15 Matteo Cobelli , Stefano Sanvito

AI explanation methods often assume a static user model, producing non-adaptive explanations regardless of expert goals, reasoning strategies, or decision contexts. Knowledge graph-based explanations, despite their capacity for grounded,…

Artificial Intelligence · Computer Science 2026-03-24 Susana Nunes , Tiago Guerreiro , Catia Pesquita

Agentic systems, in which diverse agents cooperate to tackle challenging problems, are exploding in popularity in the AI community. However, existing agentic frameworks take a relatively narrow view of agents, apply a centralized model, and…

Multiagent Systems · Computer Science 2026-01-30 Alok Kamatar , J. Gregory Pauloski , Yadu Babuji , Ryan Chard , Mansi Sakarvadia , Daniel Babnigg , Kyle Chard , Ian Foster

Autoformalization serves a crucial role in connecting natural language and formal reasoning. This paper presents MASA, a novel framework for building multi-agent systems for autoformalization driven by Large Language Models (LLMs). MASA…

Computation and Language · Computer Science 2025-10-13 Lan Zhang , Marco Valentino , André Freitas

Artificial intelligence (AI) technology has demonstrated remarkable potential in drug dis-covery, where pharmacokinetics plays a crucial role in determining the dosage, safety, and efficacy of new drugs. A major challenge for AI-driven drug…

Quantitative Methods · Quantitative Biology 2024-04-17 Ruifeng Li , Dongzhan Zhou , Ancheng Shen , Ao Zhang , Mao Su , Mingqian Li , Hongyang Chen , Gang Chen , Yin Zhang , Shufei Zhang , Yuqiang Li , Wanli Ouyang

Pruning is a promising approach to compress deep learning models in order to deploy them on resource-constrained edge devices. However, many existing pruning solutions are based on unstructured pruning, which yields models that cannot…

Machine Learning · Computer Science 2023-03-16 Kaiqi Zhao , Animesh Jain , Ming Zhao

Automated data preparation is crucial for democratizing machine learning, yet existing reinforcement learning (RL) based approaches suffer from inefficient exploration in the vast space of possible preprocessing pipelines. We present…

Databases · Computer Science 2025-07-21 Jing Chang , Chang Liu , Jinbin Huang , Rui Mao , Jianbin Qin

The emergence of large language models (LLMs) has introduced a new paradigm in automation: LLM agents or Agentic Automation with Computer Use (AACU). Unlike traditional Robotic Process Automation (RPA), which relies on rule-based workflows…

Computers and Society · Computer Science 2025-09-05 Petr Průcha , Michaela Matoušková , Jan Strnad

A general approach for building a smart assistant that guides a user from a forecast generated by a machine learning model through a sequence of decision-making steps is presented. We develop a methodology to build such a system. The system…

Artificial Intelligence · Computer Science 2021-03-31 Patrik Zajec , Jože M. Rožanec , Inna Novalija , Blaž Fortuna , Dunja Mladenić , Klemen Kenda

In drug discovery, predicting the absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties of small-molecule drugs is critical for ensuring safety and efficacy. However, the process of accurately predicting these…

Machine Learning · Computer Science 2026-03-27 Bohao Xu , Yingzhou Lu , Chenhao Li , Ling Yue , Xiao Wang , Tianfan Fu , Minjie Shen , Lulu Chen

Automating science laboratories enables faster, safer, more accurate, and more reproducible execution of protocols, accelerating the discovery and testing of new materials, drugs, and more. However, setting up and running autonomous labs…

Artificial Intelligence · Computer Science 2026-05-19 Angelos Angelopoulos , James F. Cahoon , Ron Alterovitz

Recent research in molecular discovery has primarily been devoted to small, drug-like molecules, leaving many similarly important applications in material design without adequate technology. These applications often rely on more complex…

Parameter identification for mechanistic Ordinary Differential Equation (ODE) models underpins prediction and control in several applications, yet remains a manual and labor-intensive process: datasets are noisy and partial, models can be…

Computational Engineering, Finance, and Science · Computer Science 2025-09-16 Saakaar Bhatnagar

This work evaluates the potential of large language models (LLMs) to power digital assistants capable of complex action execution. These assistants rely on pre-trained programming knowledge to execute multi-step goals by composing objects…

Modern process simulators enable detailed process design, simulation, and optimization; however, constructing and interpreting simulations is time-consuming and requires expert knowledge. This limits early exploration by inexperienced…

Chemical Physics · Physics 2026-05-22 Jingkang Liang , Niklas Groll , Gürkan Sin

Morphological profiling is a valuable tool in phenotypic drug discovery. The advent of high-throughput automated imaging has enabled the capturing of a wide range of morphological features of cells or organisms in response to perturbations…

Pharmaceutical tablet formulation and process development, traditionally a complex and multi-dimensional decision-making process, necessitates extensive experimentation and resources, often resulting in suboptimal solutions. This study…

Automated characterization of porous materials has the potential to accelerate materials discovery, but it remains limited by the complexity of simulation setup and force field selection. We propose a multi-agent framework in which…

Artificial Intelligence · Computer Science 2025-09-15 Marko Petković , Vlado Menkovski , Sofía Calero

This paper surveys the current state of the art in document automation (DA). The objective of DA is to reduce the manual effort during the generation of documents by automatically integrating input from different sources and assembling…

Computation and Language · Computer Science 2021-09-27 Mohammad Ahmadi Achachlouei , Omkar Patil , Tarun Joshi , Vijayan N. Nair

Purpose: This paper introduces the concept of "Agentic Publication," a novel LLM-driven framework designed to complement traditional scientific publishing by transforming papers into interactive knowledge systems that address challenges…

Artificial Intelligence · Computer Science 2026-05-06 Roberto Pugliese , George Kourousias , Francesco Venier , Grazia Garlatti Costa