English
Related papers

Related papers: Accelerating Antibiotic Discovery with Large Langu…

200 papers

This paper presents a knowledge management system for automobile failure analysis using retrieval-augmented generation (RAG) with large language models (LLMs) and knowledge graphs (KGs). In the automotive industry, there is a growing demand…

Artificial Intelligence · Computer Science 2024-12-02 Yuta Ojima , Hiroki Sakaji , Tadashi Nakamura , Hiroaki Sakata , Kazuya Seki , Yuu Teshigawara , Masami Yamashita , Kazuhiro Aoyama

To tackle the problem of domain-specific knowledge scarcity within large language models (LLMs), knowledge graph-retrievalaugmented method has been proven to be an effective and efficient technique for knowledge infusion. However, existing…

Computation and Language · Computer Science 2024-06-07 Zhouyu Jiang , Ling Zhong , Mengshu Sun , Jun Xu , Rui Sun , Hui Cai , Shuhan Luo , Zhiqiang Zhang

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

The worldwide increase of antimicrobial resistance (AMR) is a serious threat to human health. To avert the spread of AMR, fast reliable diagnostics tools that facilitate optimal antibiotic stewardship are an unmet need. In this regard,…

With the recent surge in popularity of Large Language Models (LLMs), there is the rising risk of users blindly trusting the information in the response, even in cases where the LLM recommends actions that have potential legal implications…

Artificial Intelligence · Computer Science 2024-10-22 George Hannah , Rita T. Sousa , Ioannis Dasoulas , Claudia d'Amato

Large Language Models (LLMs) can aid synthesis planning in chemistry, but standard prompting methods often yield hallucinated or outdated suggestions. We study LLM interactions with a reaction knowledge graph by casting reaction path…

Artificial Intelligence · Computer Science 2026-01-23 Olga Bunkova , Lorenzo Di Fruscia , Sophia Rupprecht , Artur M. Schweidtmann , Marcel J. T. Reinders , Jana M. Weber

We study how to impose domain-consistent structure on large language models (LLMs) used for scientific reasoning and early-stage drug discovery. We present MedRule-KG, a compact knowledge-graph scaffold paired with a lightweight verifier…

Artificial Intelligence · Computer Science 2025-12-15 Crystal Su

Polymer literature contains a large and growing body of experimental knowledge, yet much of it is buried in unstructured text and inconsistent terminology, making systematic retrieval and reasoning difficult. Existing tools typically…

Computational Engineering, Finance, and Science · Computer Science 2026-02-19 Sonakshi Gupta , Akhlak Mahmood , Wei Xiong , Rampi Ramprasad

As the field of Large Language Models (LLMs) evolves at an accelerated pace, the critical need to assess and monitor their performance emerges. We introduce a benchmarking framework focused on knowledge graph engineering (KGE) accompanied…

Artificial Intelligence · Computer Science 2023-09-01 Lars-Peter Meyer , Johannes Frey , Kurt Junghanns , Felix Brei , Kirill Bulert , Sabine Gründer-Fahrer , Michael Martin

Evidence-based medicine (EBM) holds a crucial role in clinical application. Given suitable medical articles, doctors effectively reduce the incidence of misdiagnoses. Researchers find it efficient to use large language models (LLMs)…

Computation and Language · Computer Science 2025-11-07 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bing Qin

Antimicrobial resistance (AMR) is escalating and outpacing current antibiotic development. Thus, discovering antibiotics effective against emerging pathogens is becoming increasingly critical. However, existing approaches cannot rapidly…

Machine Learning · Computer Science 2025-07-11 Tianang Leng , Fangping Wan , Marcelo Der Torossian Torres , Cesar de la Fuente-Nunez

Knowledge graphs (KGs) are increasingly used to represent biomedical information in structured, interpretable formats. However, existing biomedical KGs often focus narrowly on molecular interactions or adverse events, overlooking the rich…

Artificial Intelligence · Computer Science 2025-10-01 Asmita Sengupta , David Antony Selby , Sebastian Josef Vollmer , Gerrit Großmann

The rapid iteration and frequent updates of modern video games pose significant challenges to the efficiency and specificity of testing. Although automated playtesting methods based on Large Language Models (LLMs) have shown promise, they…

Artificial Intelligence · Computer Science 2025-11-05 Enhong Mu , Jinyu Cai , Yijun Lu , Mingyue Zhang , Kenji Tei , Jialong Li

One of the key requirements for incorporating machine learning into the drug discovery process is complete reproducibility and traceability of the model building and evaluation process. With this in mind, we have developed an end-to-end…

Recommender systems are pivotal in enhancing user experiences across various web applications by analyzing the complicated relationships between users and items. Knowledge graphs(KGs) have been widely used to enhance the performance of…

Information Retrieval · Computer Science 2024-07-02 Guangsi Shi , Xiaofeng Deng , Linhao Luo , Lijuan Xia , Lei Bao , Bei Ye , Fei Du , Shirui Pan , Yuxiao Li

Large Language Models (LLMs) demonstrate remarkable capabilities, yet struggle with hallucination and outdated knowledge when tasked with complex knowledge reasoning, resulting in factually incorrect outputs. Previous studies have attempted…

Computation and Language · Computer Science 2025-01-07 Derong Xu , Xinhang Li , Ziheng Zhang , Zhenxi Lin , Zhihong Zhu , Zhi Zheng , Xian Wu , Xiangyu Zhao , Tong Xu , Enhong Chen

Knowledge Graphs (KGs) have long served as a fundamental infrastructure for structured knowledge representation and reasoning. With the advent of Large Language Models (LLMs), the construction of KGs has entered a new paradigm-shifting from…

Artificial Intelligence · Computer Science 2025-10-24 Haonan Bian

An effective and efficient review of construction contracts is essential for minimizing construction projects losses, but current methods are time-consuming and error-prone. Studies using methods based on Natural Language Processing (NLP)…

Artificial Intelligence · Computer Science 2025-05-20 Chunmo Zheng , Saika Wong , Xing Su , Yinqiu Tang , Ahsan Nawaz , Mohamad Kassem

Attribution tags form the foundation of modern cryptoasset forensics. However, inconsistent or incorrect tags can mislead investigations and even result in false accusations. To address this issue, we propose a novel computational method…

Cryptography and Security · Computer Science 2025-02-18 Régnier Avice , Bernhard Haslhofer , Zhidong Li , Jianlong Zhou

Current knowledge-enhanced large language models (LLMs) rely on static, pre-constructed knowledge bases that suffer from coverage gaps and temporal obsolescence, limiting their effectiveness in dynamic information environments. We present…

Machine Learning · Computer Science 2025-10-13 Jing Li , Zhijie Sun , Zhicheng Zhou , Suming Qiu , Junjie Huang , Haijia Sun , Linyuan Qiu
‹ Prev 1 3 4 5 6 7 10 Next ›