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Transfer learning is a critical technique in training deep neural networks for the challenging medical image segmentation task that requires enormous resources. With the abundance of medical image data, many research institutions release…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Yuncheng Yang , Meng Wei , Junjun He , Jie Yang , Jin Ye , Yun Gu

Cross-modal MRI segmentation is of great value for computer-aided medical diagnosis, enabling flexible data acquisition and model generalization. However, most existing methods have difficulty in handling local variations in domain shift…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Bingnan Li , Zhitong Gao , Xuming He

Medical vision foundation models remain limited in downstream tasks, particularly volumetric medical image segmentation. While fine-tuning on labeled target-domain data improves performance, existing approaches typically rely on randomly…

Image and Video Processing · Electrical Eng. & Systems 2026-05-07 Jin Yang , Daniel S. Marcus , Aristeidis Sotiras

Test-time adaptation enables a trained model to adjust to a new domain during inference, making it particularly valuable in clinical settings where such on-the-fly adaptation is required. However, existing techniques depend on large target…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Smriti Joshi , Richard Osuala , Lidia Garrucho , Kaisar Kushibar , Dimitri Kessler , Oliver Diaz , Karim Lekadir

Most prior unsupervised domain adaptation approaches for medical image segmentation are narrowly tailored to either the source-accessible setting, where adaptation is guided by source-target alignment, or the source-free setting, which…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Xin Wang , Yin Guo , Jiamin Xia , Kaiyu Zhang , Niranjan Balu , Mahmud Mossa-Basha , Linda Shapiro , Chun Yuan

Although recent years have witnessed significant advancements in medical image segmentation, the pervasive issue of domain shift among medical images from diverse centres hinders the effective deployment of pre-trained models. Many…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Ziyang Chen , Yiwen Ye , Yongsheng Pan , Yong Xia

Medical image segmentation poses challenges due to domain gaps, data modality variations, and dependency on domain knowledge or experts, especially for low- and middle-income countries (LMICs). Whereas for humans, given a few exemplars…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Chen Xu , Qiming Huang , Yuqi Hou , Jiangxing Wu , Fan Zhang , Hyung Jin Chang , Jianbo Jiao

Medical image segmentation data inherently contain uncertainty. This can stem from both imperfect image quality and variability in labeling preferences on ambiguous pixels, which depend on annotator expertise and the clinical context of the…

Image and Video Processing · Electrical Eng. & Systems 2025-07-17 Jiayuan Zhu , Junde Wu , Cheng Ouyang , Konstantinos Kamnitsas , J. Alison Noble

Unsupervised domain adaptation is useful in medical image segmentation. Particularly, when ground truths of the target images are not available, domain adaptation can train a target-specific model by utilizing the existing labeled images…

Image and Video Processing · Electrical Eng. & Systems 2021-06-17 Fuping Wu , Xiahai Zhuang

We propose a method for test-time adaptation of pretrained depth completion models. Depth completion models, trained on some ``source'' data, often predict erroneous outputs when transferred to ``target'' data captured in novel…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Younjoon Chung , Hyoungseob Park , Patrick Rim , Xiaoran Zhang , Jihe He , Ziyao Zeng , Safa Cicek , Byung-Woo Hong , James S. Duncan , Alex Wong

Image-to-image translation has emerged as a powerful technique in medical imaging, enabling tasks such as image denoising and cross-modality conversion. However, it suffers from limitations in handling out-of-distribution samples without…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Irene Iele , Francesco Di Feola , Valerio Guarrasi , Paolo Soda

We study the problem of continual test-time adaption where the goal is to adapt a source pre-trained model to a sequence of unlabelled target domains at test time. Existing methods on test-time training suffer from several limitations: (1)…

Machine Learning · Computer Science 2024-10-03 Kien X. Nguyen , Fengchun Qiao , Xi Peng

The accurate segmentation of medical images is a crucial step in obtaining reliable morphological statistics. However, training a deep neural network for this task requires a large amount of labeled data to ensure high-accuracy results. To…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Xianjun Han , Qianqian Chen , Zhaoyang Xie , Xuejun Li , Hongyu Yang

Medical image segmentation plays a crucial role in clinical workflows, but domain shift often leads to performance degradation when models are applied to unseen clinical domains. This challenge arises due to variations in imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Yingkai Wang , Yaoyao Zhu , Xiuding Cai , Yuhao Xiao , Haotian Wu , Yu Yao

Leveraging the Segment Anything Model (SAM) for medical image segmentation remains challenging due to its limited adaptability across diverse medical domains. Although fine-tuned variants, such as MedSAM, improve performance in scenarios…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Jianghao Wu , Yicheng Wu , Yutong Xie , Wenjia Bai , You Zhang , Feilong Tang , Yulong Li , Imran Razzak , Daniel F Schmidt , Yasmeen George

Deep models often suffer from severe performance drop due to the appearance shift in the real clinical setting. Most of the existing learning-based methods rely on images from multiple sites/vendors or even corresponding labels. However,…

Image and Video Processing · Electrical Eng. & Systems 2020-09-28 Xiaoqiong Huang , Zejian Chen , Xin Yang , Zhendong Liu , Yuxin Zou , Mingyuan Luo , Wufeng Xue , Dong Ni

Medical image segmentation remains challenging in low-data regimes, where scarce annotations often yield poor generalization and ambiguous boundaries with missing fine structures. Recent self-supervised pretraining has improved…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Zhiquan Chen , Haitao Wang , Guowei Zou , Hejun Wu

We propose a new iterative segmentation model which can be accurately learned from a small dataset. A common approach is to train a model to directly segment an image, requiring a large collection of manually annotated images to capture the…

Computer Vision and Pattern Recognition · Computer Science 2018-09-13 Danielle F. Pace , Adrian V. Dalca , Tom Brosch , Tal Geva , Andrew J. Powell , Jürgen Weese , Mehdi H. Moghari , Polina Golland

Test-time adaptation (TTA) has emerged as a promising paradigm to handle the domain shifts at test time for medical images from different institutions without using extra training data. However, existing TTA solutions for segmentation tasks…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Chuyan Zhang , Hao Zheng , Xin You , Yefeng Zheng , Yun Gu

In medical image segmentation tasks, the scarcity of labeled training data poses a significant challenge when training deep neural networks. When using U-Net-style architectures, it is common practice to address this problem by pretraining…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Gábor Hidy , Bence Bakos , András Lukács