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Malignant and benign breast tumors present differently in their shape and size on sonography. Morphological information provided by tumor contours are important in clinical diagnosis. However, ultrasound images contain noises and tissue…

Computer Vision and Pattern Recognition · Computer Science 2020-09-08 Dar-Ren Chen , Yu-Chih Lin , Yu-Len Huang

Fourier ptychographic microscopy enables gigapixel-scale imaging, with both large field-of-view and high resolution. Using a set of low-resolution images that are recorded under varying illumination angles, the goal is to computationally…

Signal Processing · Electrical Eng. & Systems 2018-03-13 Emrah Bostan , Mahdi Soltanolkotabi , David Ren , Laura Waller

Fourier ptychographi cmicroscopy(FPM) is a newly developed computational imaging technique that can provide gigapixel images with both high resolution (HR) and wide field of view (FOV). However, the positional misalignment of the LED array…

Computer Vision and Pattern Recognition · Computer Science 2018-09-03 Ao Zhou , Wei Wang , Ni Chen , Edmund Y. Lam , Byoungho Lee , Guohai Situ

The progression of cancer is associated with different genetic and epigenetic events which result in nano to microscale structural alterations in cells/tissue. However, these structural alterations in the early stage of the disease remain…

This paper presents an application of digital Fourier holography for selective imaging of scatterers with different sizes in turbid media such as biological tissues. A combination of Fourier holography and high-resolution digital recording,…

Optics · Physics 2007-05-23 Sergey A. Alexandrov , P. Meredith , T. J. McIntyre , A. V. Zvyagin

Following the recent developement of Fourier ptychographic microscopy (FPM) in the visible range by Zheng et al. (2013), we propose an adaptation for hard x-rays. FPM employs ptychographic reconstruction to merge a series of low-resolution,…

Instrumentation and Detectors · Physics 2016-09-27 H. Simons , H. F. Poulsen , J. P. Guigay , C. Detlefs

The characterization of a quantum device is a crucial step in the development of quantum experiments. This is accomplished via Quantum Process Tomography, which combines the outcomes of different projective measurements to deliver a…

Quantum Physics · Physics 2025-06-26 Francesco Di Colandrea , Nazanin Dehghan , Alessio D'Errico , Ebrahim Karimi

The initial detection and identification of suspicious lesions and the precise delineation of tumour mar-gins are essential for successful tumour resection, with progression-free survival linked to rates of complete resection. However,…

In the cancer diagnosis pipeline, digital pathology plays an instrumental role in the identification, staging, and grading of malignant areas on biopsy tissue specimens. High resolution histology images are subject to high variance in…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Vasileios Magoulianitis , Catherine A. Alexander , C. -C. Jay Kuo

The realm of medical image diagnosis has advanced significantly with the integration of computer-aided diagnosis and surgical systems. However, challenges persist, particularly in achieving precise image segmentation. While deep learning…

Image and Video Processing · Electrical Eng. & Systems 2023-08-24 Mutyyba Asghar , Ahmad Raza Shahid , Akhtar Jamil , Kiran Aftab , Syed Ather Enam

Biological soft tissues encountered in clinical and pre-clinical imaging mainly consist of light element atoms, and their composition is nearly uniform with little density variation. Thus, x-ray attenuation imaging suffers from low image…

Medical Physics · Physics 2011-06-28 Wenxiang Cong , Atsushi Momose , Ge Wang

Cancer is one of the leading causes of death worldwide, making the development of rapid, minimally invasive, label-free and scalable diagnostic strategies a major challenge in modern oncology. In this context, spectroscopic liquid biopsy…

Fourier ptychographic microscopy is a computational imaging technique that provides quantitative phase information and high resolution over a large field-of-view. Although the technique presents numerous advantages over conventional…

Optics · Physics 2021-09-16 Eric Li , Stuart Sherwin , Gautam Gunjala , Laura Waller

Ptychography is an imaging technique which involves a sample being illuminated by a coherent, localized probe of illumination. When the probe interacts with the sample, the light is diffracted and a diffraction pattern is detected. Then the…

Numerical Analysis · Mathematics 2023-01-31 Mark Iwen , Michael Perlmutter , Mark Philip Roach

Pathology foundation models (PFMs) have emerged as powerful pretrained encoders for computational pathology, but their robustness under clinically relevant distribution shifts remains insufficiently understood. We benchmark the robustness…

Image and Video Processing · Electrical Eng. & Systems 2026-04-29 Fredrik K. Gustafsson , Mattias Rantalainen

Universal Lesion Detection (ULD) in computed tomography plays an essential role in computer-aided diagnosis systems. Many detection approaches achieve excellent results for ULD using possible bounding boxes (or anchors) as proposals.…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Han Li , Hu Han , S. Kevin Zhou

Each year, the treatment decisions for more than 230,000 breast cancer patients in the U.S. hinge on whether the cancer has metastasized away from the breast. Metastasis detection is currently performed by pathologists reviewing large…

Fourier ptychography (FP) is an enabling imaging technique that produces high-resolution complex-valued images with extended field coverages. However, when FP images a phase object with any specific spatial frequency, the captured images…

Cancer is an epidemic worldwide. At present one in four persons has cancer and this statistic will change to one in a two person in the near future. It is now known that war against cancer is the early, curable detection and treatment.…

Tissues and Organs · Quantitative Biology 2017-10-03 Shiva Bhandari , Sri Choudannavar , Ethan Avery , Peeyush Sahay , Prabhakar Pradhan

The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Tanvi Gupta , Pranay Manocha , Tapan K. Gandhi , RK Gupta , BK Panigrahi