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Large-scale models have exhibited remarkable capabilities across diverse domains, including automated medical services and intelligent customer support. However, as most large models are trained on single-modality corpora, enabling them to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Hao Sun , Yu Song , Jiaqing Liu , Jihong Hu , Yen-Wei Chen , Lanfen Lin

Vision-language models have become increasingly powerful for tasks that require an understanding of both visual and linguistic elements, bridging the gap between these modalities. In the context of multimodal clinical AI, there is a growing…

Computation and Language · Computer Science 2024-04-30 Masoud Monajatipoor , Zi-Yi Dou , Aichi Chien , Nanyun Peng , Kai-Wei Chang

Medical image-language pre-training aims to align medical images with clinically relevant text to improve model performance on various downstream tasks. However, existing models often struggle with the variability and ambiguity inherent in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Shreyank N Gowda , Ruichi Zhang , Xiao Gu , Ying Weng , Lu Yang

Vision-Language Models (VLMs) trained on web-scale corpora excel at natural image tasks and are increasingly repurposed for healthcare; however, their competence in medical tasks remains underexplored. We present a comprehensive evaluation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-21 Che Liu , Jiazhen Pan , Weixiang Shen , Wenjia Bai , Daniel Rueckert , Rossella Arcucci

Recent advancements in medical Large Language Models (LLMs) have showcased their powerful reasoning and diagnostic capabilities. Despite their success, current unified multimodal medical LLMs face limitations in knowledge update costs,…

Computation and Language · Computer Science 2025-06-25 Yucheng Zhou , Lingran Song , Jianbing Shen

Deep learning offers transformative potential in medical imaging, yet its clinical adoption is frequently hampered by challenges such as data scarcity, distribution shifts, and the need for robust task generalization. Prompt-based…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Hao Yang , Xinlong Liang , Zhang Li , Yue Sun , Zheyu Hu , Xinghe Xie , Behdad Dashtbozorg , Jincheng Huang , Shiwei Zhu , Luyi Han , Jiong Zhang , Shanshan Wang , Ritse Mann , Qifeng Yu , Tao Tan

The universal model emerges as a promising trend for medical image segmentation, paving up the way to build medical imaging large model (MILM). One popular strategy to build universal models is to encode each task as a one-hot vector and…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Yiwen Ye , Yutong Xie , Jianpeng Zhang , Ziyang Chen , Yong Xia

Large language models (LLMs) have shown promising capabilities in visually interpreting medical time-series data. However, their general-purpose design can limit domain-specific precision, and the proprietary nature of many models poses…

Artificial Intelligence · Computer Science 2025-07-22 Huayu Li , Zhengxiao He , Xiwen Chen , Ci Zhang , Stuart F. Quan , William D. S. Killgore , Shu-Fen Wung , Chen X. Chen , Geng Yuan , Jin Lu , Ao Li

Medical Image Retrieval (MIR) helps doctors quickly find similar patients' data, which can considerably aid the diagnosis process. MIR is becoming increasingly helpful due to the wide use of digital imaging modalities and the growth of the…

Computer Vision and Pattern Recognition · Computer Science 2020-07-20 Yang Feng , Yubao Liu , Jiebo Luo

In this paper, we introduce ILLUME, a unified multimodal large language model (MLLM) that seamlessly integrates multimodal understanding and generation capabilities within a single large language model through a unified next-token…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Chunwei Wang , Guansong Lu , Junwei Yang , Runhui Huang , Jianhua Han , Lu Hou , Wei Zhang , Hang Xu

Instruction following is crucial in contemporary LLM. However, when extended to multimodal setting, it often suffers from misalignment between specific textual instruction and targeted local region of an image. To achieve more accurate and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Jinliang Zheng , Jianxiong Li , Sijie Cheng , Yinan Zheng , Jiaming Li , Jihao Liu , Yu Liu , Jingjing Liu , Xianyuan Zhan

In clinical practice, medical image analysis often requires efficient execution on resource-constrained mobile devices. However, existing mobile models-primarily optimized for natural images-tend to perform poorly on medical tasks due to…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Fenghe Tang , Bingkun Nian , Jianrui Ding , Wenxin Ma , Quan Quan , Chengqi Dong , Jie Yang , Wei Liu , S. Kevin Zhou

Embedding models have been crucial in enabling various downstream tasks such as semantic similarity, information retrieval, and clustering. Recently, there has been a surge of interest in developing universal text embedding models that can…

Computer Vision and Pattern Recognition · Computer Science 2025-01-03 Ziyan Jiang , Rui Meng , Xinyi Yang , Semih Yavuz , Yingbo Zhou , Wenhu Chen

Digital hematopathology requires cell-level analysis across diverse disease categories, including malignant disorders (e.g., leukemia), infectious conditions (e.g., malaria), and non-malignant red blood cell disorders (e.g., sickle cell…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Abdul Rehman , Iqra Rasool , Ayisha Imran , Mohsen Ali , Waqas Sultani

In medical image analysis, the expertise scarcity and the high cost of data annotation limits the development of large artificial intelligence models. This paper investigates the potential of transfer learning with pre-trained…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Jiajin Zhang , Ge Wang , Mannudeep K. Kalra , Pingkun Yan

Integrating image and text data through multi-modal learning has emerged as a new approach in medical imaging research, following its successful deployment in computer vision. While considerable efforts have been dedicated to establishing…

Computer Vision and Pattern Recognition · Computer Science 2024-09-09 Fereshteh Shakeri , Yunshi Huang , Julio Silva-Rodríguez , Houda Bahig , An Tang , Jose Dolz , Ismail Ben Ayed

Visual Language Models (VLMs) are now increasingly being merged with Large Language Models (LLMs) to enable new capabilities, particularly in terms of improved interactivity and open-ended responsiveness. While these are remarkable…

Existing MLLM benchmarks face significant challenges in evaluating Unified MLLMs (U-MLLMs) due to: 1) lack of standardized benchmarks for traditional tasks, leading to inconsistent comparisons; 2) absence of benchmarks for mixed-modality…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Wulin Xie , Yi-Fan Zhang , Chaoyou Fu , Yang Shi , Bingyan Nie , Hongkai Chen , Zhang Zhang , Liang Wang , Tieniu Tan

The development of effective machine learning methodologies for enhancing the efficiency and accuracy of clinical systems is crucial. Despite significant research efforts, managing a plethora of diversified clinical tasks and adapting to…

Computation and Language · Computer Science 2024-06-19 Yujiang Wu , Hongjian Song , Jiawen Zhang , Xumeng Wen , Shun Zheng , Jiang Bian

The integration of AI-assisted biomedical image analysis into clinical practice demands AI-generated findings that are not only accurate but also interpretable to clinicians. However, existing biomedical AI models generally lack the ability…

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