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Conformal prediction (CP) provides a comprehensive framework to produce statistically rigorous uncertainty sets for black-box machine learning models. To further improve the efficiency of CP, conformal correction is proposed to fine-tune or…

Machine Learning · Computer Science 2025-12-03 Senrong Xu , Tianyu Wang , Zenan Li , Yuan Yao , Taolue Chen , Feng Xu , Xiaoxing Ma

Conformal prediction can be used to construct prediction sets that cover the true outcome with a desired probability, but can sometimes lead to large prediction sets that are costly in practice. The most useful outcome is a singleton…

Machine Learning · Statistics 2026-02-05 Tao Wang , Yan Sun , Edgar Dobriban

Sepsis is a severe medical condition caused by a dysregulated host response to infection that has a high incidence and mortality rate. Even with such a high-level occurrence rate, the detection and diagnosis of sepsis continues to pose a…

Applications · Statistics 2022-10-27 Jeffrey R. Smith , Yao Xie , Christopher S. Josef , Rishikesan Kamaleswaran

Epileptic seizure prediction has gained considerable interest in the computational Epilepsy research community. This paper presents a Machine Learning based method for epileptic seizure prediction which outperforms state-of-the art methods.…

Medical Physics · Physics 2021-06-09 Remy Ben Messaoud , Mario Chavez

Sepsis is a major cause of mortality in the intensive care units (ICUs). Early intervention of sepsis can improve clinical outcomes for sepsis patients. Machine learning models have been developed for clinical recognition of sepsis. A…

Applications · Statistics 2021-05-21 Jifan Gao , Philip L. Mar , Guanhua Chen

Among the main features of biological intelligence are energy efficiency, capacity for continual adaptation, and risk management via uncertainty quantification. Neuromorphic engineering has been thus far mostly driven by the goal of…

Neural and Evolutionary Computing · Computer Science 2022-11-02 Nicolas Skatchkovsky , Hyeryung Jang , Osvaldo Simeone

This paper introduces an assumption-lean method that constructs valid and efficient lower predictive bounds (LPBs) for survival times with censored data. We build on recent work by Cand\`es et al. (2021), whose approach first subsets the…

Methodology · Statistics 2023-11-08 Yu Gui , Rohan Hore , Zhimei Ren , Rina Foygel Barber

While existing depression prediction methods based on deep learning show promise, their practical application is hindered by the lack of trustworthiness, as these deep models are often deployed as black box models, leaving us uncertain on…

Machine Learning · Computer Science 2024-08-28 Yonghong Li , Xiuzhuang Zhou

We introduce a method for online conformal prediction with decaying step sizes. Like previous methods, ours possesses a retrospective guarantee of coverage for arbitrary sequences. However, unlike previous methods, we can simultaneously…

Machine Learning · Statistics 2024-05-29 Anastasios N. Angelopoulos , Rina Foygel Barber , Stephen Bates

Aligned models can misbehave in several ways: they are often sycophantic, fall victim to jailbreaks, or fail to include appropriate safety warnings. Consistency training is a promising new alignment paradigm to mitigate such failures by…

Machine Learning · Computer Science 2026-05-22 Andy Han , Kristina Fujimoto , Avidan Shah , Kiet Nguyen , Kai Xu , Chen Yueh-Han , Ilia Sucholutsky , Rico Angell

Background: Elderly patients with MODS have high risk of death and poor prognosis. The performance of current scoring systems assessing the severity of MODS and its mortality remains unsatisfactory. This study aims to develop an…

As deep learning models are increasingly deployed in high-risk applications, robust defenses against adversarial attacks and reliable performance guarantees become paramount. Moreover, accuracy alone does not provide sufficient assurance or…

Machine Learning · Computer Science 2025-06-10 Jie Bao , Chuangyin Dang , Rui Luo , Hanwei Zhang , Zhixin Zhou

Employing a machine learning approach we predict, up to 24 hours prior, a diagnosis of severe sepsis. Strongly predictive models are possible that use only text reports from the Electronic Health Record (EHR), and omit structured numerical…

Computers and Society · Computer Science 2017-12-01 Phil Culliton , Michael Levinson , Alice Ehresman , Joshua Wherry , Jay S. Steingrub , Stephen I. Gallant

In this thesis, we introduce Bayesian filtering as a principled framework for tackling diverse sequential machine learning problems, including online (continual) learning, prequential (one-step-ahead) forecasting, and contextual bandits. To…

Machine Learning · Statistics 2025-05-13 Gerardo Duran-Martin

Conformal prediction is an emerging technique for uncertainty quantification that constructs prediction sets guaranteed to contain the true label with a predefined probability. Recent work develops online conformal prediction methods that…

Machine Learning · Computer Science 2025-10-17 Huajun Xi , Kangdao Liu , Hao Zeng , Wenguang Sun , Hongxin Wei

Conformal Prediction (CP) is a powerful framework for constructing prediction sets with guaranteed coverage. However, recent studies have shown that integrating confidence calibration with CP can lead to a degradation in efficiency. In this…

Machine Learning · Computer Science 2024-07-25 Rui Luo , Nicolo Colombo

Conformal prediction has been explored as a general and efficient way to provide uncertainty quantification for time series. However, current methods struggle to handle time series data with change points - sudden shifts in the underlying…

Machine Learning · Computer Science 2025-12-02 Sophia Sun , Rose Yu

Sepsis is a major public health concern due to its high morbidity, mortality, and cost. Its clinical outcome can be substantially improved through early detection and timely intervention. By leveraging publicly available datasets, machine…

Machine Learning · Computer Science 2026-02-04 Yin Jin , Tucker R. Stewart , Deyi Zhou , Chhavi Gupta , Arjita Nema , Scott C. Brakenridge , Grant E. O'Keefe , Juhua Hu

Prediction of seizure before they occur is vital for bringing normalcy to the lives of patients. Researchers employed machine learning methods using hand-crafted features for seizure prediction. However, ML methods are too complicated to…

Machine Learning · Computer Science 2020-12-02 Khansa Rasheed , Junaid Qadir , Terence J. O'Brien , Levin Kuhlmann , Adeel Razi

Epilepsy is a neurological brain disorder which life threatening and gives rise to recurrent seizures that are unprovoked. It occurs due to the abnormal chemical changes in our brain. Over the course of many years, studies have been…

Signal Processing · Electrical Eng. & Systems 2022-10-13 Muhammad Shoaib Farooq , Aimen Zulfiqar , Shamyla Riaz