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The spread of infectious disease and the evolution of antigenically distinct strains are often modeled separately, despite strong feedbacks mediated by host immune memory and heterogeneous contacts. To tackle this challenging problem, we…

Populations and Evolution · Quantitative Biology 2026-04-01 Davide Zanchetta , Vittoria Bettio , Sandro Azaele , Manlio De Domenico

Given the growth of urbanization and emerging pandemic threats, more sophisticated models are required to understand disease propagation and investigate the impacts of intervention strategies across various city types. We introduce a fully…

Physics and Society · Physics 2020-08-03 Nishant Kumar , Jimi B. Oke , Bat-hen Nahmias-Biran

We formulate models for the spread of infection on networks that are amenable to analysis in the large population limit. We distinguish three different levels: (1) binding sites, (2) individuals, and (3) the population. In the tradition of…

Populations and Evolution · Quantitative Biology 2017-03-03 Ka Yin Leung , Odo Diekmann

Background: The global spread of the severe acute respiratory syndrome (SARS) epidemic has clearly shown the importance of considering the long-range transportation networks in the understanding of emerging diseases outbreaks. The…

Other Quantitative Biology · Quantitative Biology 2008-01-16 Vittoria Colizza , Alain Barrat , Marc Barthelemy , Alessandro Vespignani

Epidemic spreading phenomena are ubiquitous in nature and society. Examples include the spreading of diseases, information, and computer viruses. Epidemics can spread by local spreading, where infected nodes can only infect a limited set of…

Physics and Society · Physics 2024-01-02 Changwang Zhang , Shi Zhou , Joel C. Miller , Ingemar J. Cox , Benjamin M. Chain

We show that qualitatively different epidemic-like processes from distinct societal domains (finance, social and commercial blockbusters, epidemiology) can be quantitatively understood using the same unifying conceptual framework taking…

The spread of an infection on a real-world social network is determined by the interplay of two processes: the dynamics of the network, whose structure changes over time according to the encounters between individuals, and the dynamics on…

Physics and Society · Physics 2015-10-28 Lorenzo Coviello , Massimo Franceschetti , Manuel Garcia-Herranz , Iyad Rahwan

Most epidemic models assume equal mixing among members of a population. An alternative approach is to model a population as random network in which individuals may have heterogeneous connectivity. This paper builds on previous research by…

Physics and Society · Physics 2007-05-23 Erik Volz

Background: Recently developed techniques to study the spread of infectious diseases through networks make assumptions that the initial proportion infected is infinitesimal and the population behavior is static throughout the epidemic. The…

Populations and Evolution · Quantitative Biology 2012-08-17 Joel C. Miller

Physical contacts result in the spread of various phenomena such as viruses, gossips, ideas, packages and marketing pamphlets across a population. The spread depends on how people move and co-locate with each other, or their mobility…

Social and Information Networks · Computer Science 2021-12-20 Sepanta Zeighami , Cyrus Shahabi , John Krumm

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

Epidemic spreading can be suppressed by the introduction of containment measures such as social distancing and lock downs. Yet, when such measures are relaxed, new epidemic waves and infection cycles may occur. Here we explore this issue in…

Physics and Society · Physics 2020-12-07 Fabio Caccioli , Daniele De Martino

Interevent times in temporal contact data from humans and animals typically obey heavy-tailed distributions, and this property impacts contagion and other dynamical processes on networks. We theoretically show that distributions of…

Physics and Society · Physics 2022-02-08 Elohim Fonseca dos Reis , Naoki Masuda

In recent years the research community has accumulated overwhelming evidence for the emergence of complex and heterogeneous connectivity patterns in a wide range of biological and sociotechnical systems. The complex properties of real-world…

Physics and Society · Physics 2015-09-21 Romualdo Pastor-Satorras , Claudio Castellano , Piet Van Mieghem , Alessandro Vespignani

Transportation networks play a critical part in the spread of infectious diseases between populations. In this work, we define a networked susceptible-exposed-infected-recovered epidemic process with loss of immunity over time (SEIRS) that…

Optimization and Control · Mathematics 2023-09-22 Brooks A. Butler , Raphael Stern , Philip E. Paré

Human behavior plays a critical role in shaping epidemic trajectories. During health crises, people respond in diverse ways in terms of self-protection and adherence to recommended measures, largely reflecting differences in how individuals…

Physics and Society · Physics 2026-01-30 Fabio Mazza , Gabriele Ricci , Francesca Colaiori , Stefano Guarino , Sandro Meloni , Fabio Saracco

A theory of the spread of epidemics is formulated on the basis of pairwise interactions in a dilute system of random walkers (infected and susceptible animals) moving in n dimensions. The motion of an animal pair is taken to obey a…

Biological Physics · Physics 2014-08-26 V. M. Kenkre , S. Sugaya

The spread of disease through a physical-contact network and the spread of information about the disease on a communication network are two intimately related dynamical processes. We investigate the asymmetrical interplay between the two…

Physics and Society · Physics 2014-05-09 Wei Wang , Ming Tang , Hui Yang , Younghae Do , Ying-Cheng Lai , GyuWon Lee

Most spreading processes require spatial proximity between agents. The stationary state of spreading dynamics in a population of mobile agents thus depends on the interplay between the time and length scales involved in the epidemic process…

Statistical Mechanics · Physics 2024-03-05 Jorge P. Rodríguez , Matteo Paoluzzi , Demian Levis , Michele Starnini

We introduce a surveillance strategy specifically designed for urban areas to enhance preparedness and response to disease outbreaks by leveraging the unique characteristics of human behavior within urban contexts. By integrating data on…