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Cell detection and segmentation is fundamental for all downstream analysis of digital pathology images. However, obtaining the pixel-level ground truth for single cell segmentation is extremely labor intensive. To overcome this challenge,…

Computer Vision and Pattern Recognition · Computer Science 2019-10-29 Alireza Chamanzar , Yao Nie

Conventional cell tracking methods detect multiple cells in each frame (detection) and then associate the detection results in successive time-frames (association). Most cell tracking methods perform the association task independently from…

Computer Vision and Pattern Recognition · Computer Science 2020-02-27 Junya Hayashida , Kazuya Nishimura , Ryoma Bise

Classifying and analyzing human cells is a lengthy procedure, often involving a trained professional. In an attempt to expedite this process, an active area of research involves automating cell classification through use of deep…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Reece Walsh , Mohamed H. Abdelpakey , Mohamed S. Shehata , Mostafa M. Mohamed

Cells are the fundamental unit of biological organization, and identifying them in imaging data - cell segmentation - is a critical task for various cellular imaging experiments. While deep learning methods have led to substantial progress…

Semi-supervised techniques have removed the barriers of large scale labelled set by exploiting unlabelled data to improve the performance of a model. In this paper, we propose a semi-supervised deep multi-task classification and…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 R. M. Saad Bashir , Talha Qaiser , Shan E Ahmed Raza , Nasir M. Rajpoot

Mitotic activity is a crucial proliferation biomarker for the diagnosis and prognosis of different types of cancers. Nevertheless, mitosis counting is a cumbersome process for pathologists, prone to low reproducibility, due to the large…

Image and Video Processing · Electrical Eng. & Systems 2022-12-01 Claudio Fernandez-Martín , Umay Kiraz , Julio Silva-Rodríguez , Sandra Morales , Emiel Janssen , Valery Naranjo

Distributed learning has shown great potential in medical image analysis. It allows to use multi-center training data with privacy protection. However, data distributions in local centers can vary from each other due to different imaging…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Zheyao Gao , Lei Li , Fuping Wu , Sihan Wang , Xiahai Zhuang

Microscopy imaging plays a vital role in understanding many biological processes in development and disease. The recent advances in automation of microscopes and development of methods and markers for live cell imaging has led to rapid…

Computer Vision and Pattern Recognition · Computer Science 2017-05-10 Saad Ullah Akram , Juho Kannala , Lauri Eklund , Janne Heikkilä

3D microscopy is key in the investigation of diverse biological systems, and the ever increasing availability of large datasets demands automatic cell identification methods that not only are accurate, but also can imply the uncertainty in…

Computer Vision and Pattern Recognition · Computer Science 2021-02-24 Alvaro Gomariz , Tiziano Portenier , César Nombela-Arrieta , Orcun Goksel

Mixup is an efficient data augmentation approach that improves the generalization of neural networks by smoothing the decision boundary with mixed data. Recently, dynamic mixup methods have improved previous static policies effectively…

Machine Learning · Computer Science 2023-10-24 Zicheng Liu , Siyuan Li , Ge Wang , Cheng Tan , Lirong Wu , Stan Z. Li

Many fields, such as neuroscience, are experiencing the vast proliferation of cellular data, underscoring the need for organizing and interpreting large datasets. A popular approach partitions data into manageable subsets via hierarchical…

Quantitative Methods · Quantitative Biology 2024-03-07 Diek W. Wheeler , Giorgio A. Ascoli

Accurately controlling object count in text-to-image generation remains a key challenge. Supervised methods often fail, as training data rarely covers all count variations. Methods that manipulate the denoising process to add or remove…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Oz Zafar , Yuval Cohen , Lior Wolf , Idan Schwartz

Machine learning models typically focus on specific targets like creating classifiers, often based on known population feature distributions in a business context. However, models calculating individual features adapt over time to improve…

Machine Learning · Computer Science 2024-02-23 Emanuele Luzio , Moacir Antonelli Ponti , Christian Ramirez Arevalo , Luis Argerich

Large amount of image denoising literature focuses on single channel images and often experimentally validates the proposed methods on tens of images at most. In this paper, we investigate the interaction between denoising and…

Computer Vision and Pattern Recognition · Computer Science 2017-04-06 Jiqing Wu , Radu Timofte , Zhiwu Huang , Luc Van Gool

Biological cells, by definition, are the basic units which contain the fundamental molecules of life of which all living things are composed. Understanding how they function and differentiating cells from one another therefore is of…

Signal Processing · Electrical Eng. & Systems 2021-01-07 Hassan Raji , Muhammad Tayyab , Jianye Sui , Seyed Reza Mahmoodi , Mehdi Javanmard

Accurate lesion classification in Wireless Capsule Endoscopy (WCE) images is vital for early diagnosis and treatment of gastrointestinal (GI) cancers. However, this task is confronted with challenges like tiny lesions and background…

Computer Vision and Pattern Recognition · Computer Science 2024-01-12 Kunpeng Qiu , Zhiying Zhou , Yongxin Guo

Cell state discovery is crucial for understanding biological systems and enhancing medical outcomes. A key aspect of this process is identifying distinct biomarkers that define specific cell states. However, difficulties arise from the…

Human-Computer Interaction · Computer Science 2025-12-19 Rui Sheng , Zelin Zang , Jiachen Wang , Yan Luo , Zixin Chen , Yan Zhou , Shaolun Ruan , Huamin Qu

In this paper, we investigate the problem of counting rosette leaves from an RGB image, an important task in plant phenotyping. We propose a data-driven approach for this task generalized over different plant species and imaging setups. To…

Computer Vision and Pattern Recognition · Computer Science 2017-08-30 Shubhra Aich , Ian Stavness

Active learning has been demonstrated effective to reduce labeling cost, while most progress has been designed for image recognition, there still lacks instance-level active learning for object detection. In this paper, we rethink two key…

Computer Vision and Pattern Recognition · Computer Science 2023-12-29 Yuhang Zhang , Yuang Deng , Xiaopeng Zhang , Jie Li , Robert C. Qiu , Qi Tian

Decentralized optimization enables multiple devices to learn a global machine learning model while each individual device only has access to its local dataset. By avoiding the need for training data to leave individual users' devices, it…

Machine Learning · Computer Science 2026-04-22 Ziqin Chen , Zuang Wang , Yongqiang Wang