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Accurate cell counting in microscopic images is important for medical diagnoses and biological studies. However, manual cell counting is very time-consuming, tedious, and prone to subjective errors. We propose a new density regression-based…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Shenghua He , Kyaw Thu Minn , Lilianna Solnica-Krezel , Hua Li , Mark Anastasio

Dense crowd counting aims to predict thousands of human instances from an image, by calculating integrals of a density map over image pixels. Existing approaches mainly suffer from the extreme density variances. Such density pattern shift…

Computer Vision and Pattern Recognition · Computer Science 2019-08-09 Chenfeng Xu , Kai Qiu , Jianlong Fu , Song Bai , Yongchao Xu , Xiang Bai

Cell counting remains a fundamental yet challenging task in medical and biological research due to the diverse morphology of cells, their dense distribution, and variations in image quality. We present DLA-Count, a breakthrough approach to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Yuqing Yan , Yirui Wu

Tracking of plant cells in images obtained by microscope is a challenging problem due to biological phenomena such as large number of cells, non-uniform growth of different layers of the tightly packed plant cells and cell division.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Md Shazid Islam , Arindam Dutta , Calvin-Khang Ta , Kevin Rodriguez , Christian Michael , Mark Alber , G. Venugopala Reddy , Amit K. Roy-Chowdhury

For crowded scenes, the accuracy of object-based computer vision methods declines when the images are low-resolution and objects have severe occlusions. Taking counting methods for example, almost all the recent state-of-the-art counting…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Di Kang , Zheng Ma , Antoni B. Chan

Multi-class cell detection and counting is an essential task for many pathological diagnoses. Manual counting is tedious and often leads to inter-observer variations among pathologists. While there exist multiple, general-purpose, deep…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Aayush Kumar Tyagi , Chirag Mohapatra , Prasenjit Das , Govind Makharia , Lalita Mehra , Prathosh AP , Mausam

Cell detection is the task of detecting the approximate positions of cell centroids from microscopy images. Recently, convolutional neural network-based approaches have achieved promising performance. However, these methods require a…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Kazuya Nishimura , Hyeonwoo Cho , Ryoma Bise

Counting immunopositive cells on biological tissues generally requires either manual annotation or (when available) automatic rough systems, for scanning signal surface and intensity in whole slide imaging. In this work, we tackle the…

Computational Engineering, Finance, and Science · Computer Science 2026-02-27 L. Martino , M. M. Garcia , P. S. Paradas , E. Curbelo

Automatic cell detection in histology images is a challenging task due to varying size, shape and features of cells and stain variations across a large cohort. Conventional deep learning methods regress the probability of each pixel…

Computer Vision and Pattern Recognition · Computer Science 2018-06-20 Shan E Ahmed Raza , Khalid AbdulJabbar , Mariam Jamal-Hanjani , Selvaraju Veeriah , John Le Quesne , Charles Swanton , Yinyin Yuan

Automatic cell tracking in dense environments is plagued by inaccurate correspondences and misidentification of parent-offspring relationships. In this paper, we introduce a novel cell tracking algorithm named DenseTrack, which integrates…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Tanjin Taher Toma , Yibo Wang , Andreas Gahlmann , Scott T. Acton

Cornea cell count is an important diagnostic tool commonly used by practitioners to assess the health of a patient's cornea. Unfortunately, clinical specular microscopy requires the acquisition of a large number of images at different focus…

Image and Video Processing · Electrical Eng. & Systems 2020-06-08 Alon Tchelet , Leonardo Mussa , Stefano Vojinovic

High-density object counting in surveillance scenes is challenging mainly due to the drastic variation of object scales. The prevalence of deep learning has largely boosted the object counting accuracy on several benchmark datasets.…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Muming Zhao , Jian Zhang , Chongyang Zhang , Wenjun Zhang

A novel and fast semi-automatic method for segmentation, locating and counting blood cells in an image is proposed. In this method, thresholding is used to separate the nucleus from the other parts. We also use Hough transform for circles…

Image and Video Processing · Electrical Eng. & Systems 2020-04-21 Hamed Sadeghi , Shahram Shirani , David W. Capson

The need for labour intensive pixel-wise annotation is a major limitation of many fully supervised learning methods for segmenting bioimages that can contain numerous object instances with thin separations. In this paper, we introduce a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-11 Rihuan Ke , Aurélie Bugeau , Nicolas Papadakis , Peter Schuetz , Carola-Bibiane Schönlieb

This paper presents a new method for automatic quantification of ellipse-like cells in images, an important and challenging problem that has been studied by the computer vision community. The proposed method can be described by two main…

Computer Vision and Pattern Recognition · Computer Science 2012-01-17 Wesley Nunes Gonçalves , Odemir Martinez Bruno

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Every year millions of people die due to disease of Cancer. Due to its invasive nature it is very complex to cure even in primary stages. Hence, only method to survive this disease completely is via forecasting by analyzing the early…

Computer Vision and Pattern Recognition · Computer Science 2018-08-24 Shivam Singh , Stuti Pathak

Volumetric cell segmentation in fluorescence microscopy images is important to study a wide variety of cellular processes. Applications range from the analysis of cancer cells to behavioral studies of cells in the embryonic stage. Like in…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Royden Wagner , Karl Rohr

Studying the growth and metabolism of microbes provides critical insights into their evolutionary adaptations to harsh environments, which are essential for microbial research and biotechnology applications. In this study, we developed an…

Image and Video Processing · Electrical Eng. & Systems 2025-05-06 Shuang Zhang , Carleton Coffin , Karyn L. Rogers , Catherine Ann Royer , Ge Wang

Single cell segmentation is critical and challenging in live cell imaging data analysis. Traditional image processing methods and tools require time-consuming and labor-intensive efforts of manually fine-tuning parameters. Slight variations…

Quantitative Methods · Quantitative Biology 2019-04-24 Weikang Wang , David A. Taft , Yi-Jiun Chen , Jingyu Zhang , Callen T. Wallace , Min Xu , Simon C. Watkins , Jianhua Xing