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Large Language Models (LLMs) and Vision Language Models (VLMs) have recently shown promising capabilities in various scientific domain. In particular, these advances have opened new opportunities in drug discovery, where the ability to…

Artificial Intelligence · Computer Science 2026-05-13 Jueon Park , Wonjune Jang , Jiwoo Lee , Yein Park , Jaewoo Kang

As large language models (LLMs) advance, concerns about their misconduct in complex social contexts intensify. Existing research overlooked the systematic understanding and assessment of their criminal capability in realistic interactions.…

Cryptography and Security · Computer Science 2025-10-20 Xinyi Wu , Geng Hong , Pei Chen , Yueyue Chen , Xudong Pan , Min Yang

Debiasing methods that seek to mitigate the tendency of Language Models (LMs) to occasionally output toxic or inappropriate text have recently gained traction. In this paper, we propose a standardized protocol which distinguishes methods…

Computation and Language · Computer Science 2023-05-24 Robert Morabito , Jad Kabbara , Ali Emami

Text detoxification aims to minimize the risk of language models producing toxic content. Existing detoxification methods of directly constraining the model output or further training the model on the non-toxic corpus fail to achieve a…

Computation and Language · Computer Science 2024-10-14 Zecheng Tang , Keyan Zhou , Juntao Li , Yuyang Ding , Pinzheng Wang , Bowen Yan , Rejie Hua , Min Zhang

Behavioral evaluation is the dominant paradigm for assessing alignment in large language models (LLMs). In current practice, observed compliance under finite evaluation protocols is treated as evidence of latent alignment. However, the…

Machine Learning · Computer Science 2026-02-10 Igor Santos-Grueiro

Large Audio-Language Models (LALMs) are increasingly deployed in real-world applications, yet their robustness against malicious audio injection attacks remains underexplored. This study systematically evaluates five leading LALMs across…

Computation and Language · Computer Science 2025-07-11 Guanyu Hou , Jiaming He , Yinhang Zhou , Ji Guo , Yitong Qiao , Rui Zhang , Wenbo Jiang

Rapid advancements of large language models (LLMs) have enabled the processing, understanding, and generation of human-like text, with increasing integration into systems that touch our social sphere. Despite this success, these models can…

Computation and Language · Computer Science 2024-07-16 Isabel O. Gallegos , Ryan A. Rossi , Joe Barrow , Md Mehrab Tanjim , Sungchul Kim , Franck Dernoncourt , Tong Yu , Ruiyi Zhang , Nesreen K. Ahmed

Associative learning--forming links between co-occurring items--is fundamental to human cognition, reshaping internal representations in complex ways. Testing hypotheses on how representational changes occur in biological systems is…

Machine Learning · Computer Science 2025-10-27 Camila Kolling , Vy Ai Vo , Mariya Toneva

Large language models (LLMs) are commonly evaluated on challenging benchmarks such as AIME and Math500, where benchmark contamination can make memorized solutions appear as genuine reasoning. Existing detection methods largely rely on…

Computation and Language · Computer Science 2026-05-12 Zirui He , Haiyan Zhao , Yingcong Li , Ali Payani , Mengnan du

Large Language Models remain vulnerable to adversarial prompts that elicit toxic content even after safety alignment. We present ToxSearch, a black-box evolutionary framework that tests model safety by evolving prompts in a synchronous…

Neural and Evolutionary Computing · Computer Science 2026-01-27 Onkar Shelar , Travis Desell

When large language models (LLMs) are aligned to a specific online community, do they exhibit generalizable behavioral patterns that mirror that community's attitudes and responses to new uncertainty, or are they simply recalling patterns…

Computation and Language · Computer Science 2025-11-25 Patrick Gerard , Aiden Chang , Svitlana Volkova

This paper aims to help structure the risk landscape associated with large-scale Language Models (LMs). In order to foster advances in responsible innovation, an in-depth understanding of the potential risks posed by these models is needed.…

Considerable research efforts have been devoted to ensuring that large language models (LLMs) align with human values and generate safe text. However, an excessive focus on sensitivity to certain topics can compromise the model's robustness…

Computation and Language · Computer Science 2023-08-29 Huachuan Qiu , Shuai Zhang , Anqi Li , Hongliang He , Zhenzhong Lan

With the ubiquity of Large Language Models (LLMs), guardrails have become crucial to detect and defend against toxic content. However, with the increasing pervasiveness of LLMs in multilingual scenarios, their effectiveness in handling…

Computation and Language · Computer Science 2024-10-30 Yahan Yang , Soham Dan , Dan Roth , Insup Lee

Recent advances in large language models (LLMs) have enabled molecular reasoning for property prediction. However, toxicity arises from complex biological mechanisms beyond chemical structure, necessitating mechanistic reasoning for…

Quantitative Methods · Quantitative Biology 2026-04-09 Jueon Park , Wonjune Jang , Chanhwi Kim , Yein Park , Jaewoo Kang

Large language models (LLMs) are increasingly popular but are also prone to generating bias, toxic or harmful language, which can have detrimental effects on individuals and communities. Although most efforts is put to assess and mitigate…

Computation and Language · Computer Science 2024-06-26 Caroline Brun , Vassilina Nikoulina

Large language models (LLMs) are increasingly used to support the analysis of complex financial disclosures, yet their reliability, behavioral consistency, and transparency remain insufficiently understood in high-stakes settings. This…

Computation and Language · Computer Science 2026-01-21 Md Talha Mohsin

The rapid growth of the large language model (LLM) ecosystem raises a critical question: are seemingly diverse models truly independent? Shared pretraining data, distillation, and alignment pipelines can induce hidden behavioral…

Artificial Intelligence · Computer Science 2026-04-10 Chenchen Kuai , Jiwan Jiang , Zihao Zhu , Hao Wang , Keshu Wu , Zihao Li , Yunlong Zhang , Chenxi Liu , Zhengzhong Tu , Zhiwen Fan , Yang Zhou

As large language models (LLMs) are increasingly deployed in high-stakes and operational settings, evaluation strategies based solely on aggregate accuracy are often insucient to characterize system reliability. This study proposes a…

Artificial Intelligence · Computer Science 2026-05-06 Hikmat Karimov , Rahid Zahid Alekberli

Large Language Models (LLMs) have emerged as promising solutions for a variety of medical and clinical decision support applications. However, LLMs are often subject to different types of biases, which can lead to unfair treatment of…

Computation and Language · Computer Science 2024-08-23 Raphael Poulain , Hamed Fayyaz , Rahmatollah Beheshti
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