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Volumetric cell segmentation in fluorescence microscopy images is important to study a wide variety of cellular processes. Applications range from the analysis of cancer cells to behavioral studies of cells in the embryonic stage. Like in…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Royden Wagner , Karl Rohr

Precise and scalable instance segmentation of cell nuclei is essential for computational pathology, yet gigapixel Whole-Slide Images pose major computational challenges. Existing approaches rely on patch-based processing and costly…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Matěj Pekár , Vít Musil , Rudolf Nenutil , Petr Holub , Tomáš Brázdil

Semantic segmentation is the problem of assigning a class label to every pixel in an image, and is an important component of an autonomous vehicle vision stack for facilitating scene understanding and object detection. However, many of the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Christopher J. Holder , Muhammad Shafique

Few-shot image classification aims to accurately classify unlabeled images using only a few labeled samples. The state-of-the-art solutions are built by deep learning, which focuses on designing increasingly complex deep backbones.…

Computer Vision and Pattern Recognition · Computer Science 2023-07-31 Na Chen , Xianming Kuang , Feiyu Liu , Kehao Wang , Qun Chen

Recent evolution in deep learning has proven its value for CT-based lung nodule classification. Most current techniques are intrinsically black-box systems, suffering from two generalizability issues in clinical practice. First,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-28 Hanxiao Zhang , Liang Chen , Xiao Gu , Minghui Zhang , Yulei Qin , Feng Yao , Zhexin Wang , Yun Gu , Guang-Zhong Yang

Fluorescence lifetime imaging (FLI) is a widely used technique in the biomedical field for measuring the decay times of fluorescent molecules, providing insights into metabolic states, protein interactions, and ligand-receptor bindings.…

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

We developed a deep learning framework that helps to automatically identify and segment lung cancer areas in patients' tissue specimens. The study was based on a cohort of lung cancer patients operated at the Uppsala University Hospital.…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Nikolay Burlutskiy , Feng Gu , Lena Kajland Wilen , Max Backman , Patrick Micke

Accurate classification of haematological cells is critical for diagnosing blood disorders, but presents significant challenges for machine automation owing to the complexity of cell morphology, heterogeneities of biological, pathological,…

Spike sorting is a valuable tool in understanding brain regions. It assigns detected spike waveforms to their origins, helping to research the mechanism of the human brain and the development of implantable brain-machine interfaces (iBMIs).…

Signal Processing · Electrical Eng. & Systems 2025-04-22 Xiaoyu Jiang , Tao Fang , Majid Zamani

Accurate nuclei segmentation in microscopy whole slide images (WSIs) remains challenging due to variability in staining, imaging conditions, and tissue morphology. We propose CellGenNet, a knowledge distillation framework for robust…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Srijan Ray , Bikesh K. Nirala , Jason T. Yustein , Sundaresh Ram

Brightfield microscopy of unstained live cells is challenging due to low contrast, dynamic morphology, uneven illumination, and lack of labels. Deep learning achieved SOTA performance on stained, high-contrast images but needs large labeled…

Image and Video Processing · Electrical Eng. & Systems 2025-10-15 Surajit Das , Pavel Zun

Liver cancer is a leading cause of mortality worldwide, and accurate Computed Tomography (CT)-based tumor segmentation is essential for diagnosis and treatment. Manual delineation is time-intensive, prone to variability, and highlights the…

Machine Learning · Computer Science 2025-05-01 Hairong Wang , Lingchao Mao , Zihan Zhang , Jing Li

Digitization of histology images and the advent of new computational methods, like deep learning, have helped the automatic grading of colorectal adenocarcinoma cancer (CRA). Present automated CRA grading methods, however, usually use tiny…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Neda Zamanitajeddin , Mostafa Jahanifar , Nasir Rajpoot

Class distribution plays an important role in learning deep classifiers. When the proportion of each class in the test set differs from the training set, the performance of classification nets usually degrades. Such a label distribution…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Wenao Ma , Cheng Chen , Shuang Zheng , Jing Qin , Huimao Zhang , Qi Dou

Label-efficient time series representation learning, which aims to learn effective representations with limited labeled data, is crucial for deploying deep learning models in real-world applications. To address the scarcity of labeled time…

Machine Learning · Computer Science 2024-07-25 Emadeldeen Eldele , Mohamed Ragab , Zhenghua Chen , Min Wu , Chee-Keong Kwoh , Xiaoli Li

The necessity of abundant annotated data and complex network architectures presents a significant challenge in deep-learning Salient Object Detection (deep SOD) and across the broader deep-learning landscape. This challenge is particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Felipe Crispim Salvagnini , Jancarlo F. Gomes , Cid A. N. Santos , Silvio Jamil F. Guimarães , Alexandre X. Falcão

A mutation in the DNA of a single cell that compromises its function initiates leukemia,leading to the overproduction of immature white blood cells that encroach upon the space required for the generation of healthy blood cells.Leukemia is…

Computer Vision and Pattern Recognition · Computer Science 2025-01-27 Md. Abu Ahnaf Mollick , Md. Mahfujur Rahman , D. M. Asadujjaman , Abdullah Tamim , Nosin Anjum Dristi , Md. Takbir Hossen

Domain-specialized FPGAs have delivered unprecedented performance for low-latency inference across scientific and industrial workloads, yet nearly all existing accelerators assume static models trained offline, relegating learning and…

Hardware Architecture · Computer Science 2026-02-03 Duc Hoang

Segmentation and classification of cell nuclei in histopathology images using deep neural networks (DNNs) can save pathologists' time for diagnosing various diseases, including cancers, by automating cell counting and morphometric…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Amruta Parulekar , Utkarsh Kanwat , Ravi Kant Gupta , Medha Chippa , Thomas Jacob , Tripti Bameta , Swapnil Rane , Amit Sethi
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